Selective Serotonin Reuptake Inhibitor ( Ssri )

1685 WordsAug 13, 20167 Pages
Escitalopram is a second generation antidepressant; a selective serotonin reuptake inhibitor (SSRI) that is used in the treatment of major depressive disorder (MDD) and anxiety related disorders. It is generic for Lexapro and was approved by the FDA in 2012 for adults and children 12 years and older who suffer from major depressive disorder and adults who have generalized anxiety disorder. (FDA, 2012). Since its approval, Escitalopram has also been used in the treatment of Obsessive compulsive disorder, body dysmorphic disorder, and even premenstrual dysphoric disorder. This review will discuss the overall effectiveness of Escitalopram, the pharmacokinetic factors of the medication, the mechanism of action, common adverse reactions, pharmacological effects of the medication, and its efficacy across different populations. The Pharmacokinetics of Escitalopram While many selective serotonin reuptake inhibitors (SSRI’s) are accepted as first line treatments for depression and anxiety, they differ greatly in their chemical structure and pharmacokinetic profile. These differences are especially important when selecting the appropriate antidepressant drug for the client. It is also important to understand the different drug interactions and pharmacological profiles when considering an SSRI for a patient as well. An initial starting dose of escitalopram is usually 10 mg/day. It may be necessary to increase dosage after at least one week of treatment to a maximum dosage of up to 20
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