Selective Serotonin Reuptake Inhibitors (SSRI)

All antidepressants work in a similar way, though there are various types of antidepressants—often called “families”—that each work a bit differently. They all, however, increase the brain’s concentration of various neurotransmitters. Antidepressants are psychiatric medications given to patients with depressive disorders to alleviate symptoms. They correct chemical imbalances of neurotransmitters in the brain which probably cause changes in mood and behavior. Antidepressants may be used for a wide range of psychiatric conditions, including social anxiety disorder, anxiety disorders. Antidepressants were initially developed in the 1950s. Their use has become progressively more common over the last twenty years. Generally speaking, anti­psychotic

Suicide is the 6th leading cause of death for 5-14 y/o and 3rd leading cause of death for 15-24 y/o

In healthcare set up if a teenager with depression is prescribed an antidepressant the benefits and possible risks and side effects, instructions for the dose and timing, potential interactions with other prescriptions or non-prescriptions medication and alternatives to medication for example continued therapy. These medications for depression in teenagers are recommended but due to the numerous side effects associated with these drugs which is not safe for the teenagers and the availability of effective alternatives (SSRIs), TCA are less

They are usually preferred over other antidepressants as they cause fewer side effects. Fluoxetine is probably the best-known SSRI (Prozac).

Some of the most common antidepressants include Prozac, Celexa, Zoloft, Paxil, Remeron and Effexor, these come capsules or tablets, studies show that the effects of these drugs can include: Nervousness and anxiety, Insomnia, Irritability, Violent thoughts and actions, Agitation, Hostility, Suicidal thoughts or suicide, Tremors, Irregular heartbeat, Aggression, Confusion and incoherent thoughts, Paranoia, Hallucinations, Psychosis,

According to the DBSA in the US alone depression affects 6.7% of adults. This is approximately 14.8 million people who are diagnosed yearly. Depression puts you at a risk four times higher than that of a non depressed person for a heart attack. The majority of depressed peoples are women. In the medical world there are many techniques to combat depression. There are many forms of prescription antidepressants including; selective serotonin reuptake inhibitors (SSRIs), atypical antidepressants, tricyclic antidepressants (TCAs), and monoamine oxidase inhibitors (MAOIs). Thanks to Ed Likovich, Kasey Russell, Richard Schwartz, Jacqueline Olds and Tom Hayes there is another form of prescribed antidepressant that we now know as Sunsprite.

It selectively inhibit synaptic reuptake of serotonin in the presynaptic neuron, which increases the availability of serotonin in the central nervous system in the synaptic gap. SSRI’s are called ‘selective’, because they have relatively little effect on other neurotransmitters. The selectivity of SSRI’s gives them a therapeutic benefit over previous antidepressant medication. They are further the most prescribed category of antidepressants and appear to be effective in treating depressive complaints: about 50% to 55% of depressed people seem to respond positively to the drug. However, the difference with placebo is not that big, especially in people with less severe forms of

Although the treatment of choice for Generalized Anxiety Disorder is Cognitive Therapy Disorder, medications administration is often accompanied. Medications can consist of Anti-depressants, buspirone, benzodiazepines or other medications such as pregabalin, opipramol, and hydroxyzine which are not well studied. The first line medications in treatment are Anti-depressants or selective serotonin reuptake inhibitor (SSRI) and serotonin and norepinephrine reuptake inhibitor (SNRI). Which are one of the safest among the prescribed medications for generalized anxiety disorder. Benzodiazepines are often prescribed with the antidepressant because of the length of time it takes for the antidepressant to take effect (mayoclinic, 2017). Side effects

the negative side of antidepressant drugs are increase blood pressure and the need to follow particular diets . the antidepressant most prescribe today is selective serotonin reuptake inhibitors ,(SSRIS) .

A recent study examined the efficacy of treating patients with serotonin reuptake inhibitors (SSRIs) who are suffering from Major Depressive Disorder (MDD), or who are comorbid for MDD and Posttraumatic Stress Disorder (PTSD) (Sher et al., 2012). Even though SSRIs are recommended for treating these conditions, previous research findings suggested that SSRIs might be less effective for patients comorbid for MDD and PTSD. Several self-reporting instruments were used, including the Beck Depression Inventory (BDI). The BDI has been extensively tested since it was first designed by Aaron T. Beck in 1961, and has proven to be both valid and reliable (Encyclopedia of Medical Disorders, 2012).

three groups.Monoamine oxidase inhibitor (MAOI) medicines block the monoamine oxidase enzyme (MAO) from destroying monoamine neurotransmitters, which allows them to accumulate, alleviating depression. Serotonin selective reuptake inhibitor (SSRI) medications block the serotonin reuptake pump, allowing the serotonin neurotransmitter to remain and accumulate in the receptor for longer. Speaking of serotonin specifically, depression has been related to a deficiency of the 5-hydroxytryptamine (serotonin) neurotransmitter as evidenced by the concentrations of the

SSRIs are greatly chose over the other classes of antidepressants because the adverse effect of SSRIs are less prominent. SSRIs do not have the cardiac arrhythmia risk that is associated with tricyclic

The newest medications used to suppress depression are collectively known as selective serotonin inhibitors (SSRIs). These drugs work by altering the

Depression medications, including monoamine oxidase (MAO) inhibitors like isocarboxazid (Marplan) and phenelzine (Nardil); serotonin norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq) and duloxetine (Cymbalta); tricyclic antidepressants like amitriptyline; and selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa) and fluoxetine (Prozac, Sarafem)

These five classes are: SSRIs, SNRIs, Benzodiazepines, Tricyclic antidepressants and MAOIs (Monamine Oxidase Inhibitors) (Andrisano et al., 2012). The primary objectives of the study were to see which of these medications being used were considered first-line agents for treatment, and also to see if combining therapy (CBT) along with medication is more efficient in treatment than medication alone (Andrisano et al., 2012). After researchers conducted randomized trials results showed that SSRIs and SNRI venlafaxine are considered primary agents for patients with panic disorders (Andrisano et al., 2012). Both of these medications presented more tolerable side-effects and do a better job of reducing panic symptoms and anxiety levels (Andrisano et al., 2012). Results also showed that combining CBT and antidepressant medication together in treatment yielded better treatment results in 21 clinical trials and had a lower rate of relapse than with medication alone (Andriasano et al.,