Sepsis Early Detection and Treatment

1132 WordsJun 7, 20095 Pages
Running Head: SEPSIS DETECTION AND TREATMENT Sepsis Early Detection and Treatment Steven H. Gregory Chamberlain College of Nursing March28, 2009 Sepsis Early Detection and Treatment Severe Sepsis affects 750,000 Americans and causes more than 200,000 deaths annually. Sepsis is a complex condition that results from an infectious process that represents the body's response to infection and involves systemic inflammatory and cellular events that result in altered circulation and coagulation, endothelial dysfunction and impaired tissue perfusion (Kleinpell, 2005). Associated mortality rates with sepsis in the United States have remained largely unchanged for several decades. Through an international collaboration known as the…show more content…
Treatment of Sepsis As stated in Rivers, Nguyed, Havstad, Ressler, Muzzin, Knolich & et al. (2001): Early hemodynamic assessment on the basis of physical findings, vital signs, central venous pressure, and urinary output fails to detect persistent global tissue hypoxia. A more definitive resuscitation strategy involves goal-oriented manipulation of cardiac preload, afterload, and contractility to achieve a balance between systemic oxygen delivery and oxygen demand. End points used to confirm the achievement of such a balance (hereafter called resuscitation end points) include normalized values for mixed venous oxygen saturation, arterial lactate concentration, base deficit, and pH. Mixed venous oxygen saturation has been shown to be a surrogate for the cardiac index as a target for hemodynamic therapy. In cases in which the insertion of a pulmonary-artery catheter is impractical, venous oxygen saturation can be measured in the central circulation (p. 1368). The focus for the general care nurse outside of the ICU is to be able to recognize sepsis and to initiate appropriate interventions in an appropriate amount of time. Nurses need to facilitate the transfer of the patient to an ICU as urgently as possible. Once sepsis is suspected, it is important to closely monitor patients for signs and symptoms of progression with increasing frequency of assessments. While awaiting transfer of a patient to the ICU
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