Serratia Marcescens Research Paper

The route of transmission of the disease is via infected droplets that spray into the air when people cough, sneeze or talk. These droplets can then be inhaled by other people who are in close proximity to the person who is infected. Unfortunately, these droplets can remain active and contagious for several hours on a surface, such that when you touch it with your fingers and then touch your nose or mouth you can become infected. While most cases are easily diagnosed by simply looking at the patient, in the majority of cases it is preferable to have blood tests to confirm 100%. Typically the patient will have a rash that looks like small, bright Koplik’s spots on the inside

Is an infection that is life threatening and spreads to the lungs, abdomen, and urinary tract. This infection is linked to osteomyelitis, central nervous system, heart and other tissues. Symptoms include: chills, fever, rapid heartbeat, and progresses to shock, red spots on skin, and confusion.

As a facultative anaerobe, Klebsiella is usually found in human intestines or stool, where it is harmless. However, it has recently become a more important pathogen if it gets in the respiratory tract or bloodstream of a person with poor health or a compromised immune system (Guentzel, ). It commonly causes nosocomial, or hospital-acquired infections, which are contracted through the contaminated hands of healthcare workers, catheters or other equipment that is not sterile. These infections normally occur in patients that are being treated in the hospital for some other reason. Some examples of Klebsiella induced syndromes are Urinary Tract Infections, bacteremia, pneumonia, diarrhea, meningitis and osteomyelitis. According to the Pennsylvania Department of Health (2017), the mortality rate of a Klebsiella infection is around ninety percent in most countries. Additionally, it has become increasingly hard to treat infections caused by Klebsiella due to its ability to resist certain

In this lab, the organism that we have been working with is the bacterium, Serratia marcescens. S. marcescens is a member of the Enterobacteriaceae family, and tends to grow in damp environments. S. marcescens is an ideal bacterium to work with in the lab because it reproduces quicker than other bacterium. This bacterium produces a special pigment called prodigiosin, which is red in color. The prodigiosin pigment is intensified when S. marcescens is grown at higher densities. During our experiment, temperature, pH, salinity concentration and oxygen requirements were tested on S. marcescens to measure their optimal growth and prodigiosin production.

Abstract-The gram-negative bacteria Serratia marcescens has gained attention in recent years for its tendency to cause nosocomial infections in humans, as well as its development of antibiotic resistance. Antibiotic resistance in a bacterium that is harmful to humans can be concerning as it can result in infections that are difficult to treat. In order to find out more about the growing antibiotic resistance of S. marcescens, this experiment used the disc diffusion method to test the susceptibility of S. marcescens to two varieties of antibiotics that were known to have success against some gram-negative bacterium: streptomycin and ampicillin. These antibiotics were, respectively, an aminoglycoside and a beta-lactam. The experiment tested which of the two that S. marcescens had developed more of a resistance to. The zones of inhibition of the discs were significantly larger for discs treated with streptomycin compared to discs treated with ampicillin. This led to the conclusion that S. marcescens is less resistant to streptomycin than to ampicillin.

The purpose of this study was to determine what an unknown bacteria was using several different microbiology lab techniques including an API test, an oxidase test, a gram stain, a hanging drop slide, and morphology identification. The unknown bacterium, which was contaminated with Serratia marcescens, was isolated by streaking the bacteria solution to single colonies. The isolated unknown white bacteria, had the appearance of circular form, convex elevation, entire margin, elongated cocci. The tests than showed that the bacteria was gram-negative, non-motile,

Coming into lab on an urgent call Sunday morning, a report from one of the upper level floor on patient (Wall-E) that was admitted to hospital with an unknown rash to the skin. However, not knowing it was a contagious bug upon contact, 39 current inpatient were infective by it as well. Thus, antimicrobial were given per MD order, but was not effective to cure the skin rash. Hence, further tests are needed to be perform to figure out what is causing the contagious skin microbial to become resistance to the current antimicrobial given.

After microorganisms enter the patient’s body they can go to the lungs and cause pneumonia. Central line-bloodstream infections occur when microorganism enter the bloodstream by the intravenous line. Microorganisms are transfer into the blood stream by inadequate hand hygiene or improper intravenous fluid, tubing, and site care practice. Multidrug-resistant organisms can cause infections of the blood, skin, or organ systems. These infections can arise due to the overuse or misuse of antibiotics, which can result in the microorganisms becoming more resistant to antibiotic therapy. Methicillin-resistant Staphyloccocus aureus and Clostridium difficile are examples of this kind of infection. Health care employees need to know the different types of hospital acquired infections and how they are spread to be able to effectively prevent them.

“This is a very rare condition, but it still is an important condition for the scientific community to learn more about, particularly because of the potential for long-term and disabling consequences,” said Dr. Kevin Messacar, a pediatric infectious disease physician and researcher at Children’s Hospital Colorado. “Even though there are very few cases in the country, as researchers and scientists, we need to move the field forward in order to better prevent and treat the condition” he added.

The bacteria that was contained within Unknown tube #12 is believed to be Pseudomonas aeruginosa, Figure 1. The bacteria tested to be Gram Stain negative, producing a pink, red color retained from the staining process. When the species of bacteria was plated on nutrient media, the cells produced an irregular and spreading configuration as shown in Figure 2. This same plating test provided the margins and elevation, lobate and hilly, respectively. The specimen was stabbed in a Fluid Thioglycollate Medium (FTM) tube using an inoculated loop of the bacteria. The results of this experimentation indicate the type of oxygen requirement of the bacteria. The test found the bacteria to be aerobic as colonies of the bacteria began to form along the top of the FTM tube (Manual 2017).

Serratia plymuthica have received limited recognition with regards to their antimicrobial properties. Studies carried out on S.plymuthica have concentrated on the area of its pathogenecity in humans and animals. However, several reports have shown that S.plymuthica have the potential to secrete biocontrol agents against fungal pathogens. In this study, we looked at the antimicrobial production of a Seratia plymuthica strain that has the ability to inhibit various bacterial strains. The strain exhibits two phenotypic antimicrobial activities, one in the cells and the other in the supernatant. The antimicrobial compounds produced could be same or different to each other. Moreover, the compound is capable of inhibiting gram positive bacterial

Serratia marcescens is a rod-shaped gram-negative bacteria and a facultative anaerobe that can grow in the presence and absence of oxygen. It can thrive in water and in the digestive tract of some animals. It is commonly found in homes in the bathtubs and shower wall. Serratia Marcescens is a rare cause of Endogenous Bacterial Endophthalmitis. Endogenous Bacterial Endophthalmitis is an uncommon but severe infection that results in blindness or visual compromise in up to 75% of affected patients. Endogenous endophthalmitis is caused by hematogenous spread of bacteria to the eye from an extraocular focus, whereas the more common exogenous endophthalmitis occurs after ocular trauma or surgery. This infection mostly occurs in the right eye which

The aim of this experiment is to follow the growth of Serratia marcescens in nutrient broth at 37oCby recording the changes in turbidity (cloudiness) by measuring the absorbance of visible light (600 nm) and also to prove that there is an increase in the cell number and not just in mass during the growth.

Prediction: If UV light mutates the DNA of Serratia Marcescens then the red pigment colonies of the bacteria will no longer be produced.

These are gram positive bacteria which are found in acidic condition of pH 4 to 4.5 – acidophilic.