preview

Sex Exercise : Sex Determination

Better Essays

SEX DETERMINATION IN MAMMALS
Introduction:
Sex determination in mammals has always been an interesting field of study. Usually animals fall under two sex types the male and the female with some exceptions as intermediates. Sexual dimorphism were initially used to differentiate male and female with the reproductive organs. Then there was an early hypothesis that the environmental conditions such as heat of the male during the intercourse and the maternal nutrition determined the sex in mammals. This was proved wrong in the early 20th century by Painter TS who reported a sexually dimorphic chromosome in humans. The influence of environment in the sex determination was also proved true in certain species (Painter TS, 1923). The most common genetic problems that result in disorder of sex development (DSD) has raised the importance for the identification of genes responsible and their molecular mechanism in order to control these factors. Along with this, the different genetic mechanisms involved in different animals made the task to be very specific with respect to species.
Developmental Pathway:
XY cross over: Burgoyne PS, in 1982 developed a model about XY chromosomes single obligatory crossing over that resulted in the sex reversals in the mammals with an assumption of homology leading to zygotene paring of X and Y. This work was based on the study done by Ohno et al., 1959 which stated the presence of terminalised chiasma in the X and Y chromosome. The genes

Get Access