Sickle Cell Anemia Research Paper

Pain: The sickle cells are sticky and get stuck, clump together, resulting in a blockage in the flow of blood

People with sickle cell anemia also may have bouts of pain in the chest, stomach, arms, legs, or other parts of the body. This is caused by sickle cells blocking blood flow through the blood vessels. Feeling tired and having trouble fighting

This mutation paper is to give information on the Sickle Cell disease. This is a negative disease to have because the Sickle Cell Disease decreases the health of the person that has the disease and limits what they can and cannot do. Sickle Cell Disease is a red blood cell disease that causes ab normal hemoglobin to from in the veins. Hemoglobin is the protein that carries oxygen throughout the body to help with the respiratory system. The cause of the genetic mutation is inheritance or getting the disease from the parents the disease is found on chromosome 13 while the hemoglobin is still in beta phase on gene HB A. The disease typically shows symptoms within the first 5 to 6 months of birth and being diagnosed with Sickle Cell Disease. The symptoms include painful swelling on the hands and feet, and Jaundice, which causes a white color to form under the eyes, and turns the skin color yellow.

Sickle cell is a blood disease. People with sickle cell anemia have crescent moon shaped blood cells that are hard and sticky. When the Sickle cells move through blood tubes, they can clog blood flow and break apart. This can cause main, damage, and a low blood count. The symptoms of the disease are not life threatening, however are not enjoyable. Sickle cell anemia can cause you to experience dizziness, headaches, and shortness of breath. Your skin may also turn more yellow or pale than it usually is. Sickle cell is an inherited disease. It is an unpreventable disease that you are born with. If you have a sickle cell gene, you do not have sickle cell, however your children have a 25% chance of having sickle cell anemia. This blood disorder can cause pain and discomfort but it is unlikely that your life will be in danger if you have the disease.

Sickle Cell Anemia or Sickle Cell Disease (SCD) is a passed down blood disorder that attacks and destroys the red blood cells. This Disease was first discovered back in 1910. The disease was first described as a clinical entity by Herrick1 in 1910 (Anderson & Ware 1932). Sickle cell sickness is brought about by a change in the hemoglobin-Beta quality found on chromosome 11. Hemoglobin transports oxygen from the lungs to different parts of the body. Red platelets with typical (hemoglobin-An) are smooth and round and coast through veins. Typical red platelets are round like doughnuts, and they travel through little blood tubes in the body to convey oxygen. Sickle red platelets turn out to be hard, sticky and molded like sickles used to cut wheat. At times these blood cells can become crescent shaped and have a hard time passing through small blood vessels, this keeps red blood cells and the oxygen they carry from getting to all parts of the body. This causes less blood to reach the body at this point the tissues that have not received a normal blood flow will become damaged. Individuals who have sickle cell

Sickle cell anemia is one of the disease out there in the world that cannot be cured. The only thing people suffering from sickle cell can do is get treatments for the symptoms they are suffering from. Not only are there treatments, but there are also things that can be done that can prevent some of the symptoms. Some of the treatments available are different kinds of medications, vaccines, and experimental treatments. When a child suffers from sickle anemia their life could be put on line when catching an infection that may not be life threating to some who may not have that disease, so it is important for children to take antibiotics. From the antibiotics a person can take painkillers to relieve the suffer pain. A drug that is

Pain can develop when sickle shaped red blood cells block blood flow through tiny vessels to your abdomen and chest. Sickle cell can damage your spleen and since red blood cells provide your body with the oxygen and nutrients you need to grow that will be delayed. Your retina in your eyes can be damaged since tiny blood vessels that supply your eyes gets plugged with sickle cells.

Not only this disrupts oxygen from delivered, but the lack of oxygen also results in pain or crises for most. For children the pain scale can be from zero to very little pain, but for adults the pain may be severe. Doctors will often recommend the person to drink large amounts of liquid and take medications for instance ibuprofen. People with this disease are usually very tired and have a decrease in red blood cells. A normal red blood cell lives up to 120 days and automatically kills itself. A sickle cell lives up to 14 days so the body cannot necessarily keep up because the cells are rapidly

Hemoglobin is a very important protein in our blood that carries oxygen from our lungs to organs and surrounding tissues in our bodies. When hemoglobin has an inaccurate amount of production of beta globin, the normal red blood cells are changed in shape. [4] The cells also contain Hemoglobin S which is not useable within the body. The loss of oxygen and change in shape causes one hemoglobin S cell to connect to another hemoglobin S cell to form into long crystals.[3] Once changed in shape, the newly formed sickle cells are not able to pass through vessels, as normal red blood cells do, and most often result in a blockage within the body. Once a vessel is blocked, oxygen is unable to be supplied to other areas in the body causing hypoxia, or lack of oxygen. This causes an attack known as pain crises in which the

Sickle cell anemia is a severe condition in which there aren’t enough healthy, round red blood cells to carry adequate oxygen throughout your body. It is a form of anemia in which a mutated form of hemoglobin--a red protein responsible for transporting oxygen in the blood of vertebrates--distorts the red blood cells into a crescent shape. This causes low oxygen levels. Normal red blood cells are flexible and round allowing for easy movement throughout your blood vessels. In sickle cell anemia, the red blood cells are rigid and sticky and are shaped like a crescent moon--or a sickle. The effect is the red blood cells get caught in small vessels and block blood from reaching different parts of the body. This can cause pain and tissue damage.

Sickle cell anemia affects millions of people worldwide. Sickle cell anemia is a disease in which your body produces abnormally shaped red blood cells. They don't last as long as normal, round red blood cells, which leads to anemia. Sickle cells contain abnormal hemoglobin that causes the cells to have a sickle shape. Sickle-shaped cells don’t move easily through your blood vessels. They’re stiff and sticky and tend to form clumps and get stuck in the blood vessels. The sickle cells also get stuck in blood vessels, blocking blood flow. This can cause pain and organ damage. Sickle cell disease is caused by a mutation in the

For long time many people have traditions habits that help to spread sickle cell anemia in community. It is common in the east of Saudi Arabia. Because in my community some people get married of relatives, that makes disease in their children if parents have the disease. Sickle cell anemia is genetic disease, which is characterized by abnormally in the hemoglobin molecule that carries oxygen in red blood cells. It is associated with sickle cell disease with a number of acute and chronic health problems, such as acute infections, attacks of severe pain, and stroke. There is an increased risk of death. The effects of sickle cell anemia are high body temperature, bacterial infections, and lack of oxygen in the blood.

Sickle Cell Anemia or Sickle Cell Disease is an inherited blood ailment. Those suffering from Sickle Cell Disease have abnormal S/ sickle hemoglobin in the red blood cells. Hemoglobin is the protein in the blood that aids in carrying oxygen throughout the body. The ailment takes its appellation from the shape of the red blood cells of a person affected by Sickle Cell Disease, which have the shape of a sickle. They are stiff and adhesive rather than a disk like normal cells. The misshapen cells tend to get trapped in the small blood vessels hindering the movement of blood and oxygen to the many areas of one’s body. This causes pain and organ damage. Hemoglobin molecules are comprised of an alpha and a beta. People with Sickle Cell Disease have an aberration occurring on a gene in their chromosomes 11 and 16. ("Sickle Cell Disease.") Chromosome 11 is the “gene that codes for the beta subunit of the hemoglobin protein” ("Sickle Cell Disease.") This causes the particles in the hemoglobin not to manifest accurately.

The characteristic of red blood cells with sickle shape is due to the abnormal versions of beta-globin. As a consequence, the sickle-shaped red blood cells die prematurely, which lead to anemia and the person may may present shortness of breath and fatigue. In children, it can caused delayed growth and development. The sickle-shaped cells, which are rigid and unbending, get stuck in small blood vessels. As a result, the person may suffer from painful episodes, and it is possible that some tissues and organs may be deprived of oxygen, which can cause organ

Sickle cell disease causes the uniquely shaped red blood cells to obstruct the path for blood flow in the arteries. This happens due to the crescent moon shape of the red blood cells causing immense pain in the abdomen and joints and eventually, once the body can no longer transport blood effectively, death.