Sickle Cell Anemia Research Paper

Sickle cell anemia occurs when a person inherits two abnormal genes (one from each parent) that cause their red blood cells to change shape. Instead of being flexible and round, these cells are more rigid and curved in the shape of the farm tool known as a sickle - that's where the disease gets its name. The shape

When Malaria is present and infects red blood cells, parasites can infect cells carrying defective hemoglobin which may result in death. Allele frequency changes over time depending on the pressures or circumstances facing a particular population. African populations are especially impacted by both malaria and sickle cell anemia. Depending on the impacted population, allele frequency often shifts and well suited organisms are likely to survive and allele frequencies can increase. When a population is effected by disease or other circumstances, allele frequency may decrease or change. HbA (normal hemoglobin) and HbS (defective hemoglobin) have varying frequencies and while the HbS gene is present in populations it is

Discussions in regards to race can be fraught with extreme opinions, to examine this subject in a more dispassionate light it is helpful to first define the terms. Race is distinctly different from ethnicity or culture, but is often combined in both writing and thought. From a biological perspective, the description of race in human populations is meaningless, but examined from a cultural basis it can make an enormous difference to a population’s wellbeing, or survival, based solely on their difference in morphology.

Sickle cell: One of the first inherited diseases to be unraveled at the level of DNA was sickle-cell anemia which is defined as abnormal, crescent-shaped red blood cells that results from a single change in the amino acid sequence of the cell's hemoglobin, which causes the cell to contort, especially under low-oxygen conditions. (medical dictionary, 2017) Also, called drepanocyte, meniscocyte. Also, this blood disorder mostly affects Africans and natives of the Mediterranean region are those who are affected by malaria. A single mutation in the gene for the blood protein hemoglobin can affect its ability to transport oxygen around the body. People who inherit two copies of the same mutation, one from each parent, have severe symptoms.

Sickle cell anemia is an anemia that is inherited and mostly affects people whose heritage can be traced back to places where malaria was prevalent. There are approximately 100,000 Americans that have the disease and many more with the trait. Several of my family members are afflicted by this medical condition that causes red blood cells to take on an irregular shape.

This mutation paper is to give information on the Sickle Cell disease. This is a negative disease to have because the Sickle Cell Disease decreases the health of the person that has the disease and limits what they can and cannot do. Sickle Cell Disease is a red blood cell disease that causes ab normal hemoglobin to from in the veins. Hemoglobin is the protein that carries oxygen throughout the body to help with the respiratory system. The cause of the genetic mutation is inheritance or getting the disease from the parents the disease is found on chromosome 13 while the hemoglobin is still in beta phase on gene HB A. The disease typically shows symptoms within the first 5 to 6 months of birth and being diagnosed with Sickle Cell Disease. The symptoms include painful swelling on the hands and feet, and Jaundice, which causes a white color to form under the eyes, and turns the skin color yellow.

In Sickle-Cell Anemia, the 11th chromosome is affected, and thus, causes the disorder. In addition, this disease is autosomal, and not sex-linked. It is also codominant, which means neither allele

Sickle cell is a blood disease. People with sickle cell anemia have crescent moon shaped blood cells that are hard and sticky. When the Sickle cells move through blood tubes, they can clog blood flow and break apart. This can cause main, damage, and a low blood count. The symptoms of the disease are not life threatening, however are not enjoyable. Sickle cell anemia can cause you to experience dizziness, headaches, and shortness of breath. Your skin may also turn more yellow or pale than it usually is. Sickle cell is an inherited disease. It is an unpreventable disease that you are born with. If you have a sickle cell gene, you do not have sickle cell, however your children have a 25% chance of having sickle cell anemia. This blood disorder can cause pain and discomfort but it is unlikely that your life will be in danger if you have the disease.

Sickle cell anemia is a blood disorder that happen very commonly in the African descent.

Thousands of years ago, a genetic mutation occurred in people from the Mediterranean basin, India, Africa, and the Middle East. As the Malaria Epidemic attacked people of these countries, carriers of the defective hemoglobin gene survived. Carrying one defective gene means that a person has a sickle cell trait. Two parents with the trait will produce a child with sickle cell anemia. People of these countries migrated and spread to other areas. In the Western Hemisphere, where malaria is not much of a problem, having the abnormal hemoglobin gene has lost its advantage. Any child born from parents that each has the trait will be born with the disease.

The disease that I will be writing my report on is called, Sickle Cell Disease. Sickle cell disease is a disorder that affects the red blood cells, which use a protein called hemoglobin to transport oxygen from the lungs to the rest of the body. The reason I chose Sickle Cell Disease because it is occurred in mostly African-American, South America, and Caribbean islands. Also, Sickle Cell runs in my family so I thought this would be a good idea to write about it and let my class know what I know. Sickle Cell is a blood disorder. Normal blood cells and sickle cell blood cell are two totally different things. Normal blood cells are round, flexible that means they can travel through small blood vessels. Sickle cell disease causes the red blood cells to form into a crescent shape,

In this essay I will be talking about sickle cell anemia. Well I was diagnosed with the disease at birth. I have what they call SS, which means I have the full illness. The reason I do is because both of my parents have a trait. This is my story.

The sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell have red blood cells that have mostly hemoglobin's, Sometimes these red blood cells become sickle-shaped or crescent shaped and have trouble going through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can get to that part of the body. Tissue that does not get a normal blood flow eventually becomes damaged. This is what causes the problems of sickle cell disease.

Sickle-cell Anemia is a genetic disorder that causes sever pain in the lower back, legs, arms, abdomen, and chest. Red blood cells carry oxygen to the body. The body uses oxygen to make energy. Inside the red blood cell is a protein called hemoglobin, which hooks on to the oxygen. People with sickle-cell anemia have abnormal hemoglobin known as hemoglobin S. Hemoglobin S changes the blood cells into the shape of a sickle. These abnormal sickle cells stick to the blood vessel walls causing blockages. These blockages do not allow blood to flow. This is what causes the pain. People get sickle cell disease when a parent has a mutated hemoglobin gene. Their child has a chance of inheriting the sickle-cell trait or getting sickle-cell Anemia.

Sickle Cell Anemia is a very serious disorder and people suffer from it every day. It is a genetic disorder that causes the hemoglobin in the red blood cell to distort and form into a sickle like shape. The name comes from the shape of the blood cell after it is mutated. A person who has sickle cell anemia got it from inheriting from the parents. It is the most common inherited disorder in the United States. It is also has four other names this disorder can go by HbS, Hemoglobin S Disease, SCD, and Sickle Cell .(https://ghr.nlm.nih.gov)the blood cell is formed wrong turning it into a sickle or crescent shape. Sickle cell is only a disorder. It can also be treated a lot of different ways.