Sickle Cell Disease: Case Study

“In the United States, it's estimated that sickle cell anemia affects 70,000–100,000 people, mainly African Americans” (NHLBI, NIH, Who is at risk for sickle cell anemia). SCD is a disease that is a serious disorder in which the body can make normal blood cells and sickle shape cells. Sickle shape cells can block the blood flow in your vessels and cause pain or organ damage also put you in risk for infections. SCD has no cure available but there are many treatments out there to deal with the complications of it. From over years treatments did get better from way back in the day doctors have learned. Sickle cell disease has lack of attention and funding because it’s only affecting

Sickle Cell Disease is an illness that affects people all across the globe. This paper will give a description of the sickness through the discussion of the causes, symptoms, and possible cures. Sickle Cell Disease (SCD) is a "group of inherited red blood cell disorders."(1) These disorders can have various afflictions, such as pain, damage and a low blood count--Sickle Cell Anemia.

3. What skills have I acquired from the development of the GC&E Portfolio that will benefit me in the workforce, in an interview, in a career?

Health care disparity with sickle cell Disease Patient’s    Thesis Statement.   Barriers to racial health care equity include the health care system (insurance, funding), the patient (poor health literacy, fear, mistrust), the community (awareness, advocacy), and the providers (bias, attitudes, expectations, stereotyping).      Sickle cell disease (SCD) is the most prevalent genetic hematological disorder worldwide predominantly affecting populations of West African and African Caribbean descent, as well as populations of Asian, Middle Eastern, and Mediterranean origins (Burne, 2008). It affects about 80,000 people in the United States and is the most common inherited blood disorder (O’Cconnor, 2014). It affects 1 in every 500 births of African

My interest in the sickle-cell disease (also known as sickle-cell anemia), its causes and possible ways of treatment began when one of my best friends died from this sickness. In the course of my research on the subject, I came across an article titled: “Identification of Pica Behaviors in Youth with Sickle Cell Disease”; it is not only recent, but also seems to have solid research as its basis. In particular, the article researches one of the major psychological disorders from which patients with the sickle-cell disease (SCD)

Sickle cell disease (SCD) occurs in 1 out of every 365 African American births compared to 1 out of 16,000 Hispanic-American births (1). SCD is a group of red blood cell disorders in which patients have a sickle or moon-shaped red blood cell due to an abnormal S hemoglobin. While sickle cell disease is relatively rare in American births, this is an alarming statistic among people of Sub-Saharan (west and central) African descent. An interesting fact is that SCD occurs more often among people from parts of the world where malaria is or was common, such as Sub-Saharan Africa (1). In addition, it is believed that people who carry the sickle cell trait are less likely to have

Sickle cell disease (SCD) is a destructive abnormality in red blood cells that results in circulatory impairment. Sickle cell disease can cause pain, infection, organ damage and strokes. SCD is inherited through the infants’ parental genes (James, 2014). For instance, if an infant inherits the gene from one parent that infant will automatically have the sickle cell trait. As a result, the infant will be a carrier of the disease but won’t actually have the SCD. It is very rare for a carrier to have any symptoms. Women who have SCD are considered high risk if they become pregnant. SCD poses complication for both mother and fetus during

In Des Moines, Iowa a 16 year old boy by the name of Isaiah Newsome suffers from a debilitating genetic disorder called sickle cell anemia which affects mostly African Americans in the United States. Everyday Isaiah manages his pain daily by dipping into a bag of pills; blood transfusions are done every three weeks to replace the dead or misshaped cells, and for his weakened bones he has a procedure called an infusion every two months. Sickle cell anemia is a disorder that affects the red blood cell (RBC) causing it to appear under developed in a sickle shape. The shape of the sickle cell impedes on the ability of the hemoglobin (Hgb) to attach on to the RBC which deprives starving tissues and organs in rich oxygenated blood (Jackson, 2014). Some recent advancements in bone marrow transplant has proven to cure some cases of sickle cell disease but because of the risk involved with the procedure, approval to use bone marrow transplant widely has not been implemented (NHLBI 2009). By understanding sickle cell disease and increase funding for research is imperative to move forward aiding the improvements of management and treatments for sickle cell disease (SCD) with a goal of finding a cure for sickle cell.

Sickle cell disease is a blood disorder in which red blood cells take on an abnormal shape. Sickle cell anemia is when the red blood cells hemolyze, or die. Sickle cell disease is inherited from generation to generation and is the most common in inherited blood disorders. An estimated 70,000-100,000 people in America are currently suffering from this disease, most of which are African Americans. One is diagnosed with sickle cell disease in early childhood generally around four months old when the signs and symptoms are presented. Because of its huge impact, the United States requires all newborns to be tested for this disease. [1] Sickle cell disease is known to affect, “approximately 1 in every 400-500 African American

Sickle cell disease is a chronic condition that a person can inherit from their parents in which it effects the globular structure of the patients red blood cells. A more sickle shaped structure, which can alter a person’s blood flow, replaces the more common globular structure. This impairment in blood flow can lead to blood clots, severe debilitating pain and damage to vital organs such as the liver, kidney and spleen. This disease currently affects over 90,000 people in the United States, with the majority of them being African American and

Sickle Cell Disease (SCD) is an inherited autosomal recessive condition that causes the red blood cells (RBCs) to be crescent shaped. Sickle cell disease occurs in 1 out of every 400 African Americans births (Field, et al 2009). And according to the Centers of Disease Prevention and Control (CDC), 1 out of 13 African American babies are born with the sickle cell trait (SCT). At the same time SCD is present in only 1 out of 300 Caucasian babies, thus it is considered to be one of the most prevalent genetic health disparities affecting people of African, Indian, Hispanic, and Mediterranean decent (Kotch, et al 2000).

I will research what each medical school has to offer and which school I think would be the best fit. Miller School of Medicine is associated with the University of Miami but I will research to find out what it has to offer research, and residency wise. Brody School of Medicine is located in North Carolina, which would be a reason to stay here. It is a newer medical school so is a newer or older medical school better? Baylor College of Medicine is in Houston, Texas making it an outlier but is one of the top research Universities in the U.S (Best Med Schools: Research. US News & World Report).

300,000 children are born annually in the world with sickle cell, unfortunately they are usually in poor third world countries without the means to handle the epidemic. In countries such as Ghana the percentages of people that carry the trait can be upwards of 30 to 40 percent while in other parts of the continent there can be percentages upwards of 50 percent. The wide range and variation in people that carry it in different parts of the country might be connected to the different levels of malaria exposure, which I explained earlier, it appears that people with sickle cell are immune to malaria which is a bigger killer of humans in that region of the

The purpose of this essay it to determine whether or not Jonathon Jackson, a 30 year old air traffic controller whom has been faithful to his company and job for over eight years that has recently discovered he has sickle cell anemia, should be dismissed from his job regarding his genetic test results. Sickle cell anaemia is the most severe form of sickle cell disease and is a genetic disease of the red blood cells (Gibbons, 2015). Red blood cells have a disk like form which allows them the ability to travel through blood vessels. Although in people with sickle cell, the red blood cells form an abnormal crescent shape which makes them rigid and sticky as shown in Diagram 3 below. This causes the sickled cells to get trapped in small vessels which blocks blood from reaching different parts of the body leading to pain, tissue damage and many more symptoms (University of Utah, 2015). The term anaemia comes from having a shortage of red blood cells in your blood which occurs because sickled cells only last up to 10- 20 days while normal red blood cells last approximately 120 days. The name ‘sickle’ comes from an old farm tool known as a sickle as shown in Diagram 4 below which represents the same shape as curved sickled cells (Petch, 2012). Sickle cell disease affects millions of people worldwide and is most common in those who have ancestors from Africa, the Mediterranean, The Arabian Peninsula and Spanish speaking areas in South America. People with sickle cell anaemia on

Sickle cell anemia is an autosomal recessive point mutation that is often attributed to populations in Africa and the Middle East. This is due to a the high occurrence of malaria in these regions, however, the rate at which both sickle cell anemia and malaria are occurring in other regions of the globe is becoming increasingly prevalent. Immigration during the past few decades has resulted in what is now being considered an epidemic. The resources available to treat those with these diseases in more developed nations are abundant in comparison to places in Africa and the Middle East, yet regardless of treatment options, those who have sickle cell anemia still suffer greatly. How a society manages this illness is based on resources, treatment options, and funding. In some areas, sickle cell is more widespread than in others and the impact on the society yields a greater threat. In order to better understand the disease, one must start at the foundations and work upwards, following its progression and migration throughout the world.