Sickle Cell Neuron Essay

Kety asked two groups of adoptees: who had schizophrenia, and a matched group who didn’t. The disorder was related in the biological and adoptive families of the two groups of adoptees – this was larger among biological relations of the schizophrenic adoptees than between ones of the controls, this supports the genetic explanation.

In an attempt to gain a position as a psychologist, I will be discussing schizophrenia and the disorder’s casual factors, associated symptoms, the areas of the brain it affects, and the neural basis of the disorder. I will continue on to discuss appropriate drug therapies. In addition I will also be reviewing two separate case studies, each on a different disorder. I will be examining each problem from the perspective of a bio psychologist. I will define the patient’s diagnosis at length I will relate each case to the nature-nurture theory, and talk about any helpful drug interventions or solutions for each disorder. When talking about drug intervention, it is also important to discuss the positive and

believed that genetically aberrant hemoglobin evolved as a protection against malaria."(2) It has also been said that, "People with a single copy of a particular genetic mutation [sickle cell trait] have a survival advantage. One copy of the mutation confers a benefit." (3) Its quite interesting to find that original purpose of this gene was

Sickle cell anemia is a hereditary disorder that mostly affects people of African ancestry, but also occurs in other ethnic groups, including people who are of Mediterranean and Middle Eastern descent. More than 70,000 Americans have sickle cell anemia. And about 2 million Americans - and one in 12 African Americans - have sickle cell trait (this means they carry one gene for the disease, but do not have the disease itself).

Sickle Cell Disease is an autosomal recessive genetic disease that occurs due to a mutation in the β-globin gene of hemoglobin. Autosomal meaning that it is not linked to a sex chromosome, so either parent can pass on the gene to their child. This mutation is a result of a single substitution of amino acids, Glutamic for Valine at position 6 of a β globin chain. The presence of this mutation causes

The nature- nurture debate has many different case studies, which often questions environmental and hereditary aspects of the nature- nurture debate. A tangent which is focused on in this essay is how the case studies of schizophrenia and IQ, specifically affect twin and adoption studies. This essay will firstly, give a brief outline of the nature-nurture debate and the definitions of twin and adoption studies. Secondly, it will illustrate two main case studies, which are IQ and Schizophrenia studies. Thirdly, will contrast and compare the two and research’s impact on the case studies in regards to nature vs. nurture and finally, will conclude with the impact of the nature-nurture debate and twin and adoption studies.

Human cells carry two copies of each chromosome they have two versions of each gene and the different versions are called alleles. Alleles can be either dominant or recessive. Dominant alleles means you have one copy of the gene or your heterozygous. Recessive alleles means you have two copies of the gene or your homozygous.

Kety et al. (1978) examined early-age Danish adoptees matched on gender and age. 50% of these adoptees were diagnosed as schizophrenic and 50% were not. They found that the incidence of schizophrenia was greater among the biological relatives of those with schizophrenia than those without. This is expected if genetic factors are important. They also found that the rate of schizophrenia was no different for adoptive families who had adopted a child who became schizophrenic compared to those who had adopted a child that did not become schizophrenic. This therefore suggests that environment is of little importance.

When Malaria is present and infects red blood cells, parasites can infect cells carrying defective hemoglobin which may result in death. Allele frequency changes over time depending on the pressures or circumstances facing a particular population. African populations are especially impacted by both malaria and sickle cell anemia. Depending on the impacted population, allele frequency often shifts and well suited organisms are likely to survive and allele frequencies can increase. When a population is effected by disease or other circumstances, allele frequency may decrease or change. HbA (normal hemoglobin) and HbS (defective hemoglobin) have varying frequencies and while the HbS gene is present in populations it is

Westerdale, Neill, MSC, RSCN, RGN (March 2004). Managing the Problem of Pain in Adolescents with Sickle Cell Disease

According to the 2016 edition of the Oxford dictionary, to define someone or a group of people as vulnerable means that they are susceptible to physical or emotional harm (Vulnerable, 2016). One of the most recognized populations of vulnerable people are children; furthermore, by adding an inherited disease process, that decreases the immune system, would only increase the vulnerability of the population. Children with sickle cell anemia are highly susceptible to being attacked both physically and emotionally by foreign invaders that threaten their already fragile immune systems. During the process of “making hemoglobin, which carries oxygen in our red blood cells, a defect can occur when the amino acid glutamate is replaced by valine. This simple substitution can cause the red blood cell to sometimes collapse, assuming the characteristic sickle shape. The red blood cells, normally very elastic and able to conform to the shape of tiny capillary blood vessels, become rigid and can block the blood vessels, depriving tissue of oxygen and resulting in severe pain” (Stone, 2015). Sickle cell children must endure an incredible amount of pain, many hospitalizations, a pain management regimen, and the inability to experience the normal, everyday life that most of their peers participate in each day. Health care for sickle cell children is focused toward management because there is no cure and as their bodies run out of healthy red blood

The sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell have red blood cells that have mostly hemoglobin's, Sometimes these red blood cells become sickle-shaped or crescent shaped and have trouble going through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can get to that part of the body. Tissue that does not get a normal blood flow eventually becomes damaged. This is what causes the problems of sickle cell disease.

Thousands of years ago, a genetic mutation occurred in people from the Mediterranean basin, India, Africa, and the Middle East. As the Malaria Epidemic attacked people of these countries, carriers of the defective hemoglobin gene survived. Carrying one defective gene means that a person has a sickle cell trait. Two parents with the trait will produce a child with sickle cell anemia. People of these countries migrated and spread to other areas. In the Western Hemisphere, where malaria is not much of a problem, having the abnormal hemoglobin gene has lost its advantage. Any child born from parents that each has the trait will be born with the disease.

This essay will discuss whether schizophrenia is genetically inherited disorder. There will be an understanding to what schizophrenia is with a brief description in the introduction. This essay will also talk about weather schizophrenia is genetically inherited or weather it is a biological (Inherited) disorder. It will also include weather schizophrenia is cause by other factors such as social factors, environmental, pre natal, childhood and neurobiology. The essay will also state weather schizophrenia is caused by a combination of the two.

Conclusions / Results: Conclusions suggest that the nature vs nurture dichotomy may not be as relevant as looking at the interaction between these two forces. It was discovered that while one’s genetic heritage creates a predisposition towards schizophrenia, other factors such as the home environment, the parental environment, dietary factors and others may determine whether the disease is manifested.