Signs And Symptoms Of Sickle Cell Anemia

Sickle Cell Anemia is a group of disorders that cause red blood cells to become misshapen and break down. Sickle Cell Anemia affects many people all over the world; Sickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans (Ashley-Koch, Yang and Olney). Sickle Cell Anemia causes your red blood cells to be thin, stiff, and shaped like a sickle. But your red blood cells are supposed to be round and soft. When a person is diagnosed with sickle cell anemia the blood cells start to become clogged blood vessels, which can cause a great amount of health issues including: infections, stroke, and acute chest syndrome. People get sickle cell anemia by inheriting a mutated gene from both of their parents. On the down side, there is not currently an effective cure for sickle cell anemia, there are several different therapeutic approaches to treating and attempting to cure the disease and help people who are affected with sickle cell anemia better manage their symptoms. There have also been several great scientists that dedicated a lot of research to help find a cure for sickle cell anemia.

When the sickle cells go through they can block up blood vessels and cause severe pain, fatigue, paleness, rapid heart rate, shortness of breath, and/or yellowing of eyes and skin. This can also start in early childhood and cause you to have a low number of red blood cells. This disorder can affect major organs such as lungs, kidneys, spleen, and brain. Anemia can cause shortness of breath, fatigue and Delayed growth development. The severity of the pain varies from person to person. The pain is usually medium to

In order to get Sickle Cell Anemia, you must have the Sickle Cell Trait. This is defined as "A person who carries one sickle hemoglobin producing gene inherited from their parents and one normal hemoglobin gene." (3) People who only have one copy of the mutation have the trait. "It is estimated that 1 in 12 African Americans has sickle cell trait." (3) Having the trait will NOT cause SCD. However, having the gene does allow you to pass the mutation on to your children. In fact, "A child conceived by two people with sickle cell trait has one chance in two of also having sickle cell trait, one chance in four of having sickle cell anemia."(3)

People with sickle cell anemia also may have bouts of pain in the chest, stomach, arms, legs, or other parts of the body. This is caused by sickle cells blocking blood flow through the blood vessels. Feeling tired and having trouble fighting

If you have and unhealthy diet or if you are dehydrated or you get it genetically. Your symptoms are dizziness, tired or weak felling, thirsty a lot more often or thronging up also you your skin or white parts of eyes turn yellow, you get a lot of pain in your lower back, legs, arms abdomen, and chest, tempter change, stress, high altitude can also bring on Sickle Cell Disease. To help find out if you have Sickle Cell Disease you can get a bone marrow tests or a blood test, and a couple ways to help get rid of the disease you could get a bone marrow transplant or a blood transfusion. To live with it would be awful you have to get a lot of medical treatment and sometimes you don’t make it. The Sickle Cell Disease usually happens in African

This mutation paper is to give information on the Sickle Cell disease. This is a negative disease to have because the Sickle Cell Disease decreases the health of the person that has the disease and limits what they can and cannot do. Sickle Cell Disease is a red blood cell disease that causes ab normal hemoglobin to from in the veins. Hemoglobin is the protein that carries oxygen throughout the body to help with the respiratory system. The cause of the genetic mutation is inheritance or getting the disease from the parents the disease is found on chromosome 13 while the hemoglobin is still in beta phase on gene HB A. The disease typically shows symptoms within the first 5 to 6 months of birth and being diagnosed with Sickle Cell Disease. The symptoms include painful swelling on the hands and feet, and Jaundice, which causes a white color to form under the eyes, and turns the skin color yellow.

Sickle cell anemia can cause numerous symptoms, which the severity of this can vary between individuals. Symptoms that might vary from person to person that change over time, include anemia, episodes of pain, frequent infections, delayed growth, vision disorder, acute chest syndrome, and more. Indeed, of each symptom; anemia, sickle cell breaks red blood cell faster and die living people without enough red blood cells. Sickle cell anemia usually dies in 10 to 20 days while normal live for about 120 days before it replaced. Episodes of pain is a major symptom of this disease and the most common reason for people to get hospitalization; Pain develops when sickle-shaped red blood cells block blood flow through tiny blood vessels to the chest,

Sickle-cell Anemia is a genetic disorder that causes sever pain in the lower back, legs, arms, abdomen, and chest. Red blood cells carry oxygen to the body. The body uses oxygen to make energy. Inside the red blood cell is a protein called hemoglobin, which hooks on to the oxygen. People with sickle-cell anemia have abnormal hemoglobin known as hemoglobin S. Hemoglobin S changes the blood cells into the shape of a sickle. These abnormal sickle cells stick to the blood vessel walls causing blockages. These blockages do not allow blood to flow. This is what causes the pain. People get sickle cell disease when a parent has a mutated hemoglobin gene. Their child has a chance of inheriting the sickle-cell trait or getting sickle-cell Anemia.

Sickle cell anemia can produce mild to severe symptoms and complications. Anemia symptoms are tiredness, irritability, dizziness, lightheadness, a fast heart rate, difficulty breathing, pale skin color, jaundice, slow growth and delayed puberty. Hand-foot syndrome which is usually the first symptom of sickle cell anemia is the swelling of the hands and feet (“Facts About Sickle Cell Disease,” 2016). The signs and symptoms can vary from person to person and change over time in sickle cell anemia (https://www.nhlbi.nih.gov/health/health-topics/topics/sca/signs). Over time sickle cell anemia can worsen. (“Facts About Sickle Cell Disease,” 2016)

The term sickle refers to the fact that the red blood cells take on a sickle cell shape, instead of their normal biconcave shape (1). The cells can switch between the sickle shape and their normal biconcave shape (2). Sickled cells lose their pliability making it hard for the red blood cells to move through the smaller blood vessels (1). In their abnormal state they become more likely to adhere to the endothelium of the smaller vessels, causing clots to form and the possibility of stroke (2).

Sickle cell is a blood disease. People with sickle cell anemia have crescent moon shaped blood cells that are hard and sticky. When the Sickle cells move through blood tubes, they can clog blood flow and break apart. This can cause main, damage, and a low blood count. The symptoms of the disease are not life threatening, however are not enjoyable. Sickle cell anemia can cause you to experience dizziness, headaches, and shortness of breath. Your skin may also turn more yellow or pale than it usually is. Sickle cell is an inherited disease. It is an unpreventable disease that you are born with. If you have a sickle cell gene, you do not have sickle cell, however your children have a 25% chance of having sickle cell anemia. This blood disorder can cause pain and discomfort but it is unlikely that your life will be in danger if you have the disease.

The sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell have red blood cells that have mostly hemoglobin's, Sometimes these red blood cells become sickle-shaped or crescent shaped and have trouble going through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can get to that part of the body. Tissue that does not get a normal blood flow eventually becomes damaged. This is what causes the problems of sickle cell disease.

Approximately, two million Americans carry the sickle cell trait. 72,000 people are affected by sickle cell anemia in the U.S., most of whose ancestors had come from sub Saharan Africa, Spanish speaking regions, and Mediterranean countries such as Turkey, Greece, and Italy. In Hispanic American births, one in every thousand people acquire sickle cell anemia. The symptoms created by the blockage of blood flow can vary from patient to patient. Some have milder symptoms than others. Physicians use Hand-foot syndrome on patients to determine the disease. Sickle cells that clog small blood vessels in the hands and feet are one characteristic of the disease. Symptoms the patient suffers are swelling of the hands, feet and various joints. The pain

Sickle cell anemia is an anemia that is inherited and mostly affects people whose heritage can be traced back to places where malaria was prevalent. There are approximately 100,000 Americans that have the disease and many more with the trait. Several of my family members are afflicted by this medical condition that causes red blood cells to take on an irregular shape.

Sickle Cell Anemia is a group of disorders that cause red blood cells to become misshapen and break down. Sickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans (Ashley-Koch, Yang and Olney). Sickle Cell Anemia causes your red blood cells to be thin, stiff, and shaped like a sickle. But your red blood cells are supposed to be round and soft. A person that is diagnosed with sickle cell anemia, their blood cells start to become clogged, causing blood clots, which can cause a great amount of health issues including: infections, stroke, and acute chest syndrome. People get sickle cell anemia by inheriting a mutated gene from both of their parents. On the down side, there is not currently an effective cure for sickle cell anemia, there are several different therapeutic approaches to treating and attempting to cure the disease and help people who are affected with sickle cell anemia better manage their symptoms. There have also been several great scientists that dedicated a lot of research to help find a cure for sickle cell anemia.