Similarities Between Guillain-Barre Syndrome And Multiple Sclerosis

Gina is a 21-year old nursing student who saw her primary health care provider after experiencing episodic blurred vision, fatigue, poor motor coordination and urinary incontinence. Her neurological exam revealed mild ataxia and mild weakness in her left leg without severe spasticity. MRI scan of the brain reveals multiple plagues indicative of multiple sclerosis.

MS is characterized by the destruction of myelin, inflammation in the CNS and the formation of lesions in the CNS.

The central nervous system (CNS) comprises grey matter, which contains neuron cell bodies and white matter, which contains the nerve axons. Most of the nerve axons are concentrically wrapped around by lipid-rich biological membrane, known as the myelin sheath. In the CNS, myelin is produced by oligodendrocyte. a type of glial cell. (Pfeiffer et al., 1993). These electrical insulating, multilamellar membranes significantly increase the electrical resistance, in which to prevent leakage of electrical currents from the axons, as well as decrease electrical capacitance to reduce the ability of the axons to store electrical energy (Shivane &

Most people do not expect to become paralyzed during the course of their lives. Barring injury to the nervous system or debilitating disease, one does not expect to lose motor function. In spite of these expectations, people of all races, sexes, ages, and classes can be afflicted with a debilitating syndrome that can lead to difficulty in walking or even to temporary paralysis in the most severe cases. This syndrome is known commonly as Guillain-Barre Syndrome, or GBS.

In the world of neurology, there are a vast amount of neurological disorders, conditions, and diseases. One severe disease is known as Multiple Sclerosis. In this research essay, I will be discussing what multiple sclerosis is, symptoms, causes, personal experience, and treatments.

Secondary- progressive Multiple Sclerosis: it is a type of multiple sclerosis characterized by rare relapses and increased disability.

Multiple Sclerosis and Guillain-Barré Syndrome are two autoimmune disorders of the nervous system that occur when the myelin sheath surrounding the axons of a nerve degenerate. Multiple sclerosis (MS) affects the central nervous system while Guillain-Barré Syndrome (GBS) involves the peripheral nervous system.1,2 MS is a gradually regressing disease that usually occurs in one of four ways. The first is relapsing-remitting MS (RRMS) and is the most common. Patients typically experience relapses where the symptoms are aggravated and enhanced followed by episodes of remissions during which the symptoms cease or calm down. 3 The second type is called secondary-progressive MS (SPMS). This type mimics RRMS but undergoes a steadier decline that may or may not include relapses3. The third type is primary-progressive MS (PPMS) where the disease progresses at a more regular rate from onset. PPMS, however, may speed up, slow down, or even plateau for a bit, but no remissions are present.3 Lastly, progressive-relapsing MS (PRMS), the least common type, presents similarly to PPMS in that the decline is steady, but this type of MS has exacerbations that the patient may or may not recover from.3 Unlike MS, Guillain-Barré does not present in types and characteristically attacks more rapidly.2 It is a poorly understood disease, however, research has shown that it is generally preceded by a bacterial or viral infection.4

MS(Multiple Sclerosis) is a disease which gradually hardens all tissues and also causes scars. These scars form when the persons immune system's cells go into the central nervous system and cause inflammation to the brain, spinal cord and optic nerves. MS is also a non contagious and unpredictable disease. MS is also the most common chronic disease (when it comes to the CNS (Central Nervous System)) with young Australians. Throughout all the states of Australia, Victoria is the State with the most people that have the condition.

Incurable disease? No not me. At the young age of only fourteen I had been diagnosed with an incurable disease that would change my life FOREVER. This disease called, Multiple Sclerosis, is a non-curable neurological disease that impacts the nerves in your brain and spinal cord. It can be hereditary in some ways, but doctors have yet to find a direct cause of the disease itself. Symptoms can range from tingling or pinprick feelings, to blurred vision, and even the loss of mobility in your limbs and in other areas of your body. This disease has impacted me more than physically, it has impacted me emotionally and spiritually as well. Although, this is a serious medical condition, I have overcome and learned to accept the fact that I am a little different than everyone else.

The central nervous system is made up of the brain and spinal cord. The brain is connected to the spinal cord. The brain helps interpret information received from the spinal cord. Through the spinal cord signals are sent to the rest of body and back to the brain. Nerve cells (neurons) are found in the nervous system and they help communicate with other cells through electrical signals. Some of the nerve cells are coated with a myelin sheath. Myelinated neurons allow electrical signals to travel at a faster speed. When the myelinated part of the nerve cell is destroyed, Multiple Sclerosis (MS) can be the one to blame.

Multiple Sclerosis (MS) a disease which the immune system attacks the protective sheath also known as the myelin that covers the nerves. Damages myelin disrupts the communication between the brain and the rest of the body. The nerves itself may weaken, process that is currently irreversible.

If you know anyone with Multiple Sclerosis or MS, you would know how terrible the disease is. Multiple Sclerosis is an inflammatory disease in which your immune system attacks the nerve cell covers in the brain and spine are damaged. The nerves in the body eventually deteriorate and it is fatal. According to the National Multiple Sclerosis Society, the cause of Multiple sclerosis is still unknown. There is not a cure at the moment for Multiple Sclerosis, but there are treatments that can speed recovery when attacked by the disease (Mayo Clinic). Scientists are under the impressions that there are a few factors that may come into play. They say that when they discover the exact cause of Multiple Sclerosis it will be easier to find a way to treat the disease or maybe even stop it from happening at all. (National Multiple Sclerosis Society)

The four subtypes are progressive relapsing MS (PRMS), secondary progressive MS (SPMS), primary progressive MS (PPMS), and relapsing/ remitting MS (RRMS). RRMS is the most common type and can be broken up more to active or not active as well as worsening or not worsening. It is said that 85% of patients diagnosed with RRMS will eventually move on to SPMS. There needs to be a complete neurological exam and medical history before someone can be labeled with the disease. There is not a clear cut test for MS but there are other tests that can be completed to rule out other conditions that have similar signs and symptoms of MS. Such tests include a MRI, blood test, or looking at the cerebrospinal fluid (CSF) after obtaining it from a spinal tap. The blood test is used to check for other diseases. With the MRI of the head and spine, there should be a presence of plaques. These plaques can cause lesions in the affected

Multiple Sclerosis is an autoimmune disorder which is characterized by multiple areas of scarring to nerve fibers of the CNS. It often affects people between 20 to 40 years. Currently there are about 1.1 million people suffering from multiple sclerosis. Like most of the autoimmune diseases females are more affected than males in this disease. Multiple Sclerosis effects the central nervous system (brain and spinal cord). The disease commences with a discrete attack known as CIS (clinically isolated syndrome), which may attack any area of the CNS but mostly attacks either the brain stem, optic nerve or spinal cord.

Multiple Sclerosis (MS) is an autoimmune disease of the Central Nervous System, which interferes with the communication between the Central Nervous System (brain and spinal cord) and other parts of the body. The immune system attacks the myelin on the nerve fibers; resulting in damaged myelin that forms sclerosis. Overtime, many nerve fibers and myelin sheath will be damaged or even destroyed, resulting in the nerve impulse being interrupted. MS can be mild, moderate, or severe, therefore, it may cause disability as well as death. Interestingly enough, more women are affected than men. Common signs and symptoms of multiple sclerosis include: fatigue, difficulties with walking (gait), spasticity, numbness/tingling, weakness, vision problems, pain, vertigo, depression, emotional changes, cognitive changes, bladder/bowel problems, and sexual problems. Less common signs and symptoms include: speech/swallowing problems, seizures, tremor, breathing problems, headache, pruritus, and hearing loss. There a four different types of Multiple Sclerosis: Relapsing-remitting MS (RRMS), Secondary Progressive MS (SPMS), Primary-progressive MS (PPMS), and Progressive-relapsing MS (PRMS). Relapsing-remitting Multiple Sclerosis is the most common type of MS; about 85% of people are diagnosed with this type of Multiple Sclerosis. Relapsing-remitting Multiple Sclerosis is characterized by worsening neurologic function attacks throughout the disease. The attacks are also known