Similarities and Dissimilarities in Transcription and Replication

680 Words Feb 7th, 2018 3 Pages
The similarities are the following:
Both processes use similar nucleotide building blocks
They use the same chemical method of attack on the same triphosphate group of an incoming nucleotide. The attack too is perpetrated by the -OH final group of the growing chain
Both processes are perpetrated by the hydrolysis of the pyrophosphate group that is released upon instigation of the attack.

Differences between transcription and replication
The differences include the following:
DNA replication copies the entire helix, whilst DNA transcription copies only specific regions of one strand of the helix.
During DNA transcription only short region (about 60 base pairs) of the template DNA helix are unwound. More and more is unwound as the RNS polymerase continues to transcribe. With replications, however, the parent helix remains separated from DNA helix until the process of replication is complete.
DNA replication and transcription contain slight differences in their substrates. The DNA nucleotides are deoxyribonucleotide triphosphates. The RNA ones are, however, different consisting of v, meaning that they possess the -OH group. In RNA, too, the thymine group contains the base uracil. The DNA does not have this and both of these differences are manifested in DNA transcription.
DNA replication too only occurs at certain moments in a cell's life and is a thoroughly regulated process. DNA…