Single fiber electromyography (SFEMG) is another reliable diagnostic test for MG. This test typically requires the use of a specialized EMG needle electrode that is inserted into a single muscle in rapid succession in order to measure muscle “jitter” or fatigue (Selvan, 2011). This test measures electrical impulses and activity between the brain and the muscle, and detects individual muscle weakness. To establish possible MG in a patient, there are more jitters shown in weaker muscles. SFEMG is highly sensitive and requires great technical expertise to administer.
Unintelligible speech or other voice disorders may be treated by an otolaryngologist, also known as an ear, nose, and throat doctor. Since vocal difficulties are common…show more content… Although in some cases spontaneous improvement or remission has been reported, this is not common, and patients should seek treatment in order to cope with MG (Sieb, 2014); however MG is rarely life-threatening. Since many treatments for MG are successful, general outlook for patients is bright, especially in terms of quality of life and daily functioning (Sieb, 2014).
There is currently no cure for MG, however there are multiple treatments available to manage the disease. Depending on the state of the individual, practitioners will recommend a specific treatment protocol by evaluating the short and long-term cost-benefits of available treatment options. These treatments include: plasma exchange and IVIG, acetylcholinesterase (AChE) inhibitors, immunosuppressants, and a thymectomy.
Plasma exchange (plasmapheresis) and IVIg are treatments used for acute management of severe muscular weakness. Symptoms usually improve for 1 to 2 months, and each treatment is commonly used in conjunction with immunosuppressants (Skeie, et al., 2010). Plasma exchange involves replacing plasma with 1-1.5 times the volume with saline, albumin, or plasma protein fraction (Newsom-Davis, 2003). Ideally, by replacing the plasma there will be a reduced amount of AChR antibodies attacking AChRs. IVIg (Intravenous immunoglobulins involves administration of immunoglobulins (antibodies) that inhibit cytokines,