The skin is known as the largest organ in the body, They are the largest in weight and in surface area. Also the skin separates the body’s inside environment from the outside environment. The skin has a lot of different roles. It acts as a channel of communication with the outside would skin protects the body from water loss it uses specialized pigment cells, called melanocytes, to protect the body from ultraviolet radiation skin participates in calcium homeostasis by contributing to the body’s supply of vitamin D skin also helps regulate body temperature and metabolism.
Elastic tissues such as the skin must have a strong and resilient structural framework. This framework is called the extracellular matrix, or connective tissue. The orientation
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Many features of skin and connective tissue disorders overlap with each other, and with other disorders, even though they have unique genetic causes.
A connective tissue disease is any disease that affects the parts of the body that connect the structures of the body together.
Connective tissues are made up of two proteins: collagen and elastin. Collagen is a protein found in the tendons, ligaments, skin, cornea, cartilage, bone, and blood vessels. Elastin is a stretchy protein that is like a rubber band and is the major component of ligaments and skin. When a patient has a connective tissue disease, the collagen and elastin are inflamed. The proteins and the body parts they connect are harmed.
There are several different types of connective tissue diseases. They can be inherited or caused by environmental factors. Connective tissue disease just like:
Rheumatoid arthritis: Rheumatoid arthritis is one of the most common connective tissue diseases and can be inherited. Ra is an autoimmune disease. That means the immune system attacks its own body. In this systemic disorder, immune cells attack and inflame the membrane around its joints. It also can affect the heart, lungs, and eyes. It affects a lot more women than
Our bone tissues are made of a much harder substance than the cartilage, but they can be worn away by friction. They are tough on the outside, but on the inside they have a sponge-like design that helps to reduce the weight while retaining strength. They are designed to maintain the body’s structure and support the body’s movement and are used to protect weaker tissues, such as the brain, lungs and heart.
The body has different organs that work together and they make up a system such as the
The skin is the largest organ of the body and it acts as a waterproof protector for all of the internal organs, it is comprised of several layers including the Epidermis which is the outer layer and is a protective multi-layered self renewing structure which varies in thickness depending on which part of the body it covers. Under this is the Dermis, this is a layer of connective tissue which provides the skins elasticity and strength, it also contains sensory nerve endings, blood and lymph vessels, sebaceous and sweat glands. Under this layer is the Subcutaneous fat layer, this layer separates the skin from the underlying bone and muscle with a rich blood supply it also serves as an insulator and energy store. Pressure ulcers develop
Connective tissue - Connective tissues holds and binds everything together which are found all around the body. This type of tissue is also called fibrous connective tissues as they are consisting of a lot of fibres eg. Collagen and Elastin.
They are very strong, yet lightweight. Dense connective tissue, are cells crowded between collagen fibers. Loose connective tissue is the most common type of tissue in vertebrates. It holds the organs in place, and attaches to epithelial tissue. Reticular connective tissue is found around the liver, the kidney, the spleen, the lymph nodes, and in bone marrow. It forms a soft skeleton that supports. Blood is used to transport oxygen and nutrients to the cells.
It protects the body from ultraviolent rays from the sun due to the presence of melanin from melanocytes. This radiation can damage the DNA and lead to diseases such as cancer
The second type of tissue found in the body is connective tissue. They lie beneath the epithelial tissue helping to connect different part of the internal structure, the cells are more widely separated from each other then in epithelial tissue. The intercellular substance known as the matrix is found in considerably large amounts. Within the matrix there are usually fibres which may be a jelly like consistency or dense and rigid depending on the type, function and positioning of the tissue. Theses fibres form a supporting system for cells to attach to. The major functions of connective tissue are to transport materials, give structural support and protection. The types of connective tissue that will be explained are blood, bone, cartilage, bone, areolar tissue and adipose tissue.
Elhers-Danlos syndrome, EDS is a group of inherited connective tissue disorder. Elhers-Danlos syndrome is a rare genetic disease caused by defects in the structure and synthesis of connective tissue protein: collagen. Collagen is the most predominant component of connective tissues such as skin, tendon, cornea and bones, making up more than 90% of the extracellular matrix protein (Uitto, 1986). Collagen is a strong, fibrous protein found throughout the body. It provides strength and support to the skin, bone, muscles, blood vessels, ligaments and many tissues and organs in the body. Research statistics show that 1 in 5000 people have EDS. This rare disease is prevalent in men and women of all racial and ethnic backgrounds (EDNF, 2016). In the past, Ehlers-Danlos syndrome had more than ten recognized types, each differentiated by Roman numerals. In 1997, researchers proposed a simpler method to classify these ten types and reduced the number of major
Although the specific cause of Scleroderma is unknown, there are a few main factors known to identify with Scleroderma. Scleroderma affects not only the surface of the skin but the joints, bones and in severe cases other internal organs such as heart, liver, kidneys, and gastrointestinal system. The main causes are over production of collagen and damage to blood pathways which lead to a change in connective tissue. The overproduction of collagen is due to the hyperactivity of the autoimmune system which signals the body to produce more collagen than needed which leads to thickening of the skin, therefore restricting normal function.
Lupus is a chronic inflammatory disease marked by its effect on various parts of the body, including the joints, skin, blood, and kidneys. It is a condition in which the body's immune system attacks its own cells and tissues, resulting in pain, inflammation, and often damage to organs. Lupus involves the immune system. The immune system makes antibodies that work to protect the body against foreign substances like viruses and bacteria. Such foreign bodies are called antigens. When a person has lupus, his or her body is unable to determine the difference between antigens and the individual's cells and body tissues. As such, the immune system creates antibodies against the individual's own tissues. These antibodies are called autoantibodies. Depending on the type of lupus, a wide range of symptoms may be experienced, from rashes, hair loss, and achy, swollen joints to fever, anemia, and abnormal blood clotting. Though the disease can affect many parts of the body, individuals usually experience symptoms in only a few organs. There is no known cure for lupus. However,
It is composed of highly vascular connective tissue (Stocum, 2006). The dermis contains a rich supply of blood; these blood vessels dilate and contract in response to internal and external stimuli such as anxiety and temperature (Bowers, Thompson, & Miller, 1992). The dermis is therefore responsible for regulating body temperature and blood pressure (Kemble & Lamb, 1984). The blood from the dermis is responsible for the nourishment of newly generated cells in the inner layer of the epidermis (MacDonald, 2009). The function of the dermal connective tissue is to provide structural support for the outer layer of the skin (Martini, Ober, & Bartholomew, 1999). Sensory nerve fibres can also be found in the dermis, which respond to touch, pain and temperature (Bryant & Nix, 2012). This serves an important role in human well-being, allowing us to respond to dangers such as being burnt by a hot object. The organisation of connective tissue permits the dermis to be flexible and contract with the movement of the body (Starcher, 2005). This flexibility provides the body with a barrier to protect it from friction and impact wounds (Hess, 2013). The thickness of the dermis varies across different areas of the
This vast world is filled with millions of different diseases, and they can be categorized just as many ways. One category in which they can be broken down into can be an autoimmune disease. An autoimmune disease is a disease where the body’s immune system attacks itself. This group of diseases can be broken down even further into many specific diseases, for example rheumatoid arthritis. Rheumatoid arthritis is defined as a chronic inflammatory disease that affects the joints in the body, particularly the joints in the hands and feet. An article written in 2014 by Rawlings and Choy digs deeper into this disease and aries a few questions that I’ll discuss later.
Skin disease is distraction happen in skin (4). The Skin diseases are common condition in the world. Some of Skin disease occurs in specific places in the skin. Some of diseases occur in the faces and other occur behind knees and other occur in the hand or legs .Three of more common diseases of skin happen is skin cancer, eczema , acne .This essay will discuss the definition of Skin Disease, similarities between skin cancer and eczema, and differences between them.
Our skin is the largest part of our body and needs constant care and miniaturization to achieve a healthy glow. First thing to healthy-looking skin is maintaining an internal regimen; drinking lots of water and eating fruits and veggies will keep skin nourished, moisturized and blemish free.