Skin Regeneration Paper

Describe the series of events that occur in skin, which is healing with the help of a skin graft?

This is a 52-year-old male with a 9/24/2014 date of injury. A specific mechanism of injury has not been described.

For my practice I was fortunate to be able to work at the Bethany in Cochrane. This facility was well kept and has much of the equipment to properly and holistically care for their residents. While in practice, I was able to help with a variety of tasks, including morning care and bed making. An essential element of morning care was a skin assessment, typically to look for bruises, dry spots, and most importantly, ulcers. Ulcers are painful and can decrease quality of life (Ricci, 2013).

The main outcome measures were the percent area of the wound compared to baseline area of the wound. As the wound decreased in size it is theoretically assumed that the wound is healing. The central concepts of the study were based on ultraviolet-C positive effects on wound healing in vitro. In vitro studies effects include; modification of growth factors, fibronectin release from fibroblast, epidermal cell proliferation, killing of pathogens, accelerated DNA synthesis, and antibiotic-resistant organisms.

This study considered a skinfold assessment performed at the right triceps and the measurement of the body fat percentage by mean of a Bioelectrical impendance machine (BIM). This is a more complex method. It is hypothesised that there is a positive linear relationship between skinfold thickness and body fat

More specifically, the body recognizes the antigen proteins on the connective tissues as damaged tissue or foreign bodies. As a result, the autoimmune system goes into its defense mode which is a hyperactive state. In this state, it produces an excess of antibodies and growth factors. Growth factors are a hormone or substance that is required to stimulate growth or synthesis in cells. The specific chemicals that are produced are cytokines and chemokines. Furthermore, cytokines and chemokines which are produced in the blood are the chemical growth factors that assist with scar tissue repair by defending the body. It does this by stimulating the

The main outcome measures were the percent area of the wound compared to baseline area of the wound. As the wound decreased in size it is theoretically assumed that the wound is healing. The central concepts of the study were based on ultraviolet-C positive effects on wound healing in vitro. In vitro studies effects include; modification of growth factors, fibronectin release from fibroblast, epidermal cell proliferation, killing of pathogens, accelerated DNA synthesis, and antibiotic-resistant organisms.

In light of how incredible our body is to be able to regenerate quickly for most, that is not what happens for others. Many diseases or large body wounds can take years to make it through one stage. Some may not ever heal. Wounds such as diabetic, venous stasis, ischemic, or pressure ulcers have a lack of blood flow making it almost impossible for them to heal naturally (Cutroneo, 2008). Large area burn victims also fall into this category. Their body is trying to compensate for fluid loss and maintain homeostasis, but wound healing ends up being very difficult to do on their own (Jacobsen, 2005). Many attempts are used to heal these including gene therapy, hydrotherapy, hyperbaric oxygen therapy, and topical antibiotics to just name a few. There are many courses of therapy to heal these wounds, and some work better than others depending on the wound and person.

Many studies on wound healing stages have found abnormal changes in remolding stage, and the main change in this stage was the imbalance in collagen production and degradation. This imbalance in collagen production and degradation was hypothesized to be the cause of keloid scars formation. Although many studies have been conducted on keloid in order to understand its pathophysiology, the full picture of keloid pathophysiology still unclear yet. For the sake of keloid treatment, many treatment regimens were invented to overcome formation of keloid scar as a complication after wound healing. Although there have been many scholars work on finding a treatment for keloid, there are many obstacles to reach the complete cure and avoid recurrence. Keloid treatments were categorized into three categories. These categories are noninvasive medical therapies, surgical and other invasive therapies, and therapies under investigation. In Noninvasive medical therapies category, the majority of treatments in this category exert their effects mainly throughout repression of the fibroblast proliferation rate, ECM synthesis, collagen synthesis, inflammation, enhancing of MMP expression in order to reduce the keloid scar formation. Surgical and other invasive therapies category, although this type of treatment is very popular, it has a high rate of recurrence when it is used alone. Many studies on keloid have shown that the combination therapy is the best therapy, and it has been shown that it reduces the rate of recurrence. For instance, combination of cryotherapy therapy or the surgical management with corticosteroid or 5-Flourouracil therapy was found to give clinical outcomes better than use of either therapy alone. Therapeutic under investigation category, it is including all new therapies

Skin resurfacing improves the rejuvenation of the skin by stimulating fibroblasts, the cells that are responsible for the production of collagen that gives the skin its youthfulness and elasticity. As the time passes, smoking, age and exposure to sun cause the breaking down of collagen which is why saggy skin and fine wrinkles may appear. Differences in pigment and texture are also the consequence of age, acne and sun damage. The treatments such as dermabrasion and laser treatments may help this process and help even in facial scar removal.

Wound healing is a dynamic process consisting of four continuous, overlapping, and precisely programmed phases. The events of each phase must happen in a precise and regulated manner. Interruptions, aberrancies, or prolongation in the process can lead to delayed wound healing resulting in a non-healing chronic wound.

The skin is a wonderful organ that covers the entire human body. It is made up of two layers- the dermis and the epidermis. The outside layer of the skin (the part that we see) is the epidermis. That has all of our pores (the little openings in our skin) and hairs. The inside layer of the skin (the part we don't see) is the dermis. That has nerves, blood vessels, hair roots, and glands. There are pigment cells in the skin that give the skin it's color. If the cells have a lot of melanin, then the person will be darker. Melanin causes freckles, too. Skin is important because it protects our bodies from the sun. Without it, the sun would burn up all of the good cells in our body. Good skin helps our body keep a normal temperature, which means

Stunning and flawless skin is what every girl and woman wishes for. These days whether or not you're a student, homemaker or a corporate professional, it's important to have glowing and healthy skin. This can be the primary thing people notice in you and it undoubtedly makes a smart impression on the others. Each girl is born with gorgeous skin and it's up to you to take proper care of it.

Since reaching the age of 44 years old activities that 40 year olds do has not stopped me from being active. Besides recognizing and feeling the age of 40 something it feels great nothing has changed, the only thing that comes upon me is the maturity and experience of what to do and how to do it. Age has not crept up on me yet I only have one gray hair in the middle of my scalp, I feel well rested physically and mentally being 44 years old. People in their 40s’ complain about their health, keeping youth, how long to live by making too many doctors’ appointments, and getting tarot cards or zodiac readings. By the time I got to my forties strangers wanted to know what products I use to stay youthful. As a result of keeping the crow’s feet off my eyes and mouth, there are special kinds of lotions and creams I use to stop the process of any effects of skin aging and damage from happening.

As we get older, our muscles and tissues gradually begin to lose some of their elasticity. This is a natural process caused by a combination of aging and the effects of gravity. The most obvious visual result of this process is wrinkling of the skin. Many people turn to products like Skin Rejuvenation Gel to delay or offset the natural effects of aging.