Smallpox has been a feared disease throughout history due to huge epidemics resulting in a large number of deaths (Carson- Dewitt 2006). The name Smallpox, or the Variola Virus, was common around 570 AD and introduced by Bishop Marious of Avenches. Variola derives from the Latin word various meaning stained or various or mark on the skin (Milton 2012). Milder patterns of the virus can be called cotton pox, white pox, and the Cuban itch (OMICS International 2006). The word smallpox was first used in 15th century England in order to tell the difference between syphilis called “great pocks”, and the variola virus (Riley 2006).
Smallpox is believed to have first appeared around 10,000 BC and spread by Egyptian merchants. The earliest evidence
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People with smallpox are highly contagious during the first week because of the large amount of virus present in their saliva. Contaminated clothing in bed linen can also spread the virus, although it is less common and less effective (Carson-Dewitt 2006). Incubation of the virus can last two weeks and show no symptoms. In the latent period the incubation can last four to fourteen days while the virus multiplies. The prodromal stage occurs next. This is when the mouth and skin become infected. The prodromal phase can last two to three days (Breman & Henderson 2002). After the incubation is finished the virus erupts from infected cells releasing particles which in turn go on to infect other cells in the body. The symptoms will then appear abruptly as body parts are increasingly taken over by the virus (Carson-Dewitt 2006). The bodyś immune system tries to ward off the persistent symptoms and causes a fever to occur. Large amounts of the virus can be found in organs such as the spleen, lymph nodes, liver, bone marrow, and kidneys (Breman & Henderson 2002). The viruses linear genome consists of roughly 200 genes involved in the replication of the virus within the body. The variola virus belongs to the genus Orthopoxvirus which its members produce lesions on the skin of mammals (Bray & Buller 2004). Smallpox is strictly an infection that affects human beings. It does not affect animals …show more content…
Coagulopathy is a condition in which the blood's ability to coagulate or form clots becomes impaired. This condition can cause prolonged or excessive bleeding (Tomislav 2015). These are caused by an inflammatory response to the virus affecting cells in the body (Bray & Buller 2004). Bacterial infections from the open skin lesions, bone infections, and pneumonia are major factors contributing to the death rate of smallpox (Carson-Dewitt 2006). Death occurs in 30% of smallpox cases (Turkington & Ashby 2007). Pitted lesions are visible on the body of survivors dating back to the 1000 BC (Berman & Henderson 2002).
The smallpox virus can be mistaken for scabies chicken pox or herpes. The electron microscope can see the virus within the patient's urine or blood before a rash has developed. If progressed enough a physical examination would be able to determine the virus (Carson-Dewitt 2006). The characteristic rash along with known exposure to the virus were important factors when diagnosing patients with smallpox (CDC
I looked at everything I could access related to smallpox. The writings included many references to
Smallpox is a viral infection caused by Variola major. This infection is currently one of the most dreaded diseases, and is believed to be more dangerous than the enemy’s sword. The exposure is usually an infection of the respiratory tract. After exposure, early symptoms are: headaches, back aches, fever, vomiting, discomfort, and feeling out of sorts. These symptoms go away usually in two days, and the patient feels better. Then about two days later, the patient has a flustered face, and lesions on the mouth, throat, and nasal membranes. At 5 days past exposure, red rashes and bumps appear on the skin, bleeding through skin, and mucous membranes. If the patients bleeds through their eyes, gums, or nose, the patient will not live much longer, but that is not usually the case. The bumps may touch each other or they may be separate from each other. If the bumps do not touch, the patients has a good chance of surviving. But if the bumps do touch, the patient has a forty percent chance of surviving. Dehydration is common in patients because it may be painful or difficult to drink. Around day ten, the bumps will become soft, and blisters will form. The fluid in the bumps is absorbed because of dehydration. A smell often comes from cracked bumps, and a second bacterial infection may occur due to the openings in the body. Two weeks after initial symptoms, the bumps and blisters are replaced by scabs. One week later the fever disappears, the patient returns to a normal life, and the
There are many mysteries about the smallpox virus. Since the seventeenth century, doctors have understood that if the pustules merge into sheets across the body the victim will usually die: the virus has split the whole skin. If the victim survives, the pustules turn into scabs and fall off, leaving scars. This is known as ordinary smallpox.
What is smallpox? The internet has defined it as an “acute contagious immune disease, with fever and pustules (small bumps on the skin filled with pus) that will usually will leave scars.” Smallpox originated in India and Egypt over 3,000 years ago. After that it slowly started to progress to other areas across the world. It then started to show itself in places like Africa, Europe and then after a few years later, finally made it’s way into the Americas during the 1500’s.
Smallpox is an extremely deadly disease which, in one point in time, was the most feared disease on the planet. In the book Pox Americana, Elizabeth A. Fenn writes about the encounter with the deadly disease in the 1770's to the 1780's. Her book was first published in 2001 in New York City, where she originally wrote it. Her book contains just under 400 words that explain the disease, some of the first encounters with it, who and where it affected people, and how they got the epidemic under control. Pox Americana is a very informative book that teaches the reader various things.
become known as pustules. The rash becomes fully developed between 12 and 14 days after the symptoms of the disease appear. As the disease follows its course, symptoms become more and more severe and uncomfortable for the patient. Red spots on the patient begin to turn black, while others turn white, the individual experiences strong delirium, hemorrhages of blood at the anus, mouth, and nose, raw flesh from the stripping of the skin, and fistulous ulcers in the ligaments, body, limbs, and joints. Smallpox is also associated with the unbelievable amount of swelling and protuberance in the throat and eyes, which obstruct vision as well as the ability to swallow and perform similar functions. The virus also causes the rotting of the ligaments and bones.
Smallpox was most commonly brought to America during the eighteenth century by English immigrants or recently
Smallpox, also know as variola virus, is extremely contagious and lethal. In modern day it has been eradicated and we no longer vaccinate the human population. Symptoms begin 12-14 days after infection; after 1-2 days spots turn into blisters and then pustules and after 8-9 days these pustules become crusted. If the person survives, large disfiguring scars remain (Merck, 2003).
Smallpox was a very devastating disease during the mid-1700’s and killed over 400,000 people annually across Europe. Smallpox spread rapidly and was a very contagious disease. Smallpox was caused by the variola virus and after being infected with the disease people would experience symptoms that included headaches, chills, backaches, fever, rashes along with a breakout of pimples. People who were infected with the variola virus would recuperate, however, three out of ten people would die. Fortunately, in July 1796, a rural physician named Edward Jenner found the variolation procedure to prevent people from developing the severe virus of smallpox.
The Ruination of Smallpox Diseases have been around since the beginning of time. Some have come and gone without being noticed. Others however, have come and destroyed civilizations. They can do everything from causing a cough to viciously scaring their victims and in the worst cases, even killing them. The worst of all of them is Smallpox.
Smallpox is an infectious virus that has influenced people for many centuries. Smallpox got its name from a latin word called ¨spotted¨ since you get those bumps that are red all over your body. You could easily prevent this disease.
Smallpox is an acute contagious viral disease, with fever and pustules usually leaving permanent scars. Although there is no cure, there is a vaccine that can help protect you from it. It is called vaccinia and is a poxvirus closely related to the smallpox. Live vaccinia infects the people but it does not make them sick. A smallpox particle can either make or consist of around two hundred different types of protein. In the center of the mulberry of a smallpox particle, there is an odd shape that looks like a dumbbell, this is the
Smallpox is extremely dangerous because there is no known cure. Smallpox can spread through the air and physical contact with the pox marks or anything that the pox marks touch. The Variola Virus spread so quickly that it caused over 50 million infections per year. Symptoms of Smallpox include vomiting, chills, fever, rashes, malaise, blisters,
Smallpox is provoked by the virus variola. It infiltrates through the lungs and is transferred in the blood to numerous internal organs. It is then dispersed to the skin, where it causes a rash. This “treatment” for the virus had already been
Imagine a quick spreading rash throughout the entire body, leaving not a single space behind; every opening and crevice in your body, including your mouth and eyes covered in painful bumps accompanied by high fever and severe body aches. Flat red spots transforming into fluid-filled lesions and soon oozing out yellow pus, evidently emitting a pungent odor to anyone who dared get close. The live virus present in the darkening crusty scabs that would soon fall off only to leave behind a deep pitted scarred filled complexion on anyone who was fortunate enough to survive. These scars would be forever remembered as the hallmark for the smallpox epidemic which tormented the world for over 3,000 years. (Riedel “Deadly Diseases”).