Smallpox: The Variola Virus

Smallpox is an extremely deadly disease which, in one point in time, was the most feared disease on the planet. In the book Pox Americana, Elizabeth A. Fenn writes about the encounter with the deadly disease in the 1770's to the 1780's. Her book was first published in 2001 in New York City, where she originally wrote it. Her book contains just under 400 words that explain the disease, some of the first encounters with it, who and where it affected people, and how they got the epidemic under control. Pox Americana is a very informative book that teaches the reader various things.

Smallpox is a disease caused by a poxvirus that is caught from person to person that causes high fever, and rash, that can kill about 1/3 of those who caught the disease. Smallpox (also called variola) is the only disease that has been fully cured. Smallpox is also almost one of the most scary deaths ever. Not one documented naturally occurring case of this very infectious, deadly disease hasn't occurred since 1977. (An unvaccinated hospital cook in Somalia was the last person to naturally contract smallpox.) The World Health Organization (WHO) officially declared smallpox eradicated in

I looked at everything I could access related to smallpox. The writings included many references to

Smallpox was most commonly brought to America during the eighteenth century by English immigrants or recently

What is smallpox? The internet has defined it as an “acute contagious immune disease, with fever and pustules (small bumps on the skin filled with pus) that will usually will leave scars.” Smallpox originated in India and Egypt over 3,000 years ago. After that it slowly started to progress to other areas across the world. It then started to show itself in places like Africa, Europe and then after a few years later, finally made it’s way into the Americas during the 1500’s.

Smallpox virus's scientific name is variola. It means "spotted" in Latin, and it was given to the disease by a medieval bishop. The virus, as a life form, comes in two subspecies:

Smallpox is a virus that was first founded in ancient times. The virus?s proper name is Variola rex, and it has various different forms as well as various symptoms. Among these forms are typical smallpox, hemorrhagic smallpox, and malignant smallpox, all of which usually always cause death in their victims. Some of the typical symptoms of smallpox include red vesicles and pustules all over, bleeding from all orifices of the body, swelling in the face, throat, and eyes, difficulty eating and swallowing, delirium, malaise, deterioration of the bone marrow, lymph nodes and mucus membranes of the body, and a multitude of other secondary symptoms. Smallpox is typically diagnosed by ruling out the possibility of other

Smallpox, also know as variola virus, is extremely contagious and lethal. In modern day it has been eradicated and we no longer vaccinate the human population. Symptoms begin 12-14 days after infection; after 1-2 days spots turn into blisters and then pustules and after 8-9 days these pustules become crusted. If the person survives, large disfiguring scars remain (Merck, 2003).

Smallpox is a viral infection caused by Variola major. This infection is currently one of the most dreaded diseases, and is believed to be more dangerous than the enemy’s sword. The exposure is usually an infection of the respiratory tract. After exposure, early symptoms are: headaches, back aches, fever, vomiting, discomfort, and feeling out of sorts. These symptoms go away usually in two days, and the patient feels better. Then about two days later, the patient has a flustered face, and lesions on the mouth, throat, and nasal membranes. At 5 days past exposure, red rashes and bumps appear on the skin, bleeding through skin, and mucous membranes. If the patients bleeds through their eyes, gums, or nose, the patient will not live much longer, but that is not usually the case. The bumps may touch each other or they may be separate from each other. If the bumps do not touch, the patients has a good chance of surviving. But if the bumps do touch, the patient has a forty percent chance of surviving. Dehydration is common in patients because it may be painful or difficult to drink. Around day ten, the bumps will become soft, and blisters will form. The fluid in the bumps is absorbed because of dehydration. A smell often comes from cracked bumps, and a second bacterial infection may occur due to the openings in the body. Two weeks after initial symptoms, the bumps and blisters are replaced by scabs. One week later the fever disappears, the patient returns to a normal life, and the

The first case of smallpox was found on the ancient Egyptian Pharaoh Ramses V in the 3rd Century BCE. After Egypt, in the 4th Century, variola is thought to have spread to China, where people prayed to the god Yo Hoa Long to try to prevent themselves getting sick, of course, this was to no prevail. After spreading to China, because of the increasing trade with Japan and Korea, smallpox spread even further. This deadly pathogen spread quickly, as somebody only needed to be breathed on, and they could be infected. During the 7th century, smallpox was widespread throughout India and was quickly spreading towards northern Africa, Spain, and Portugal because of the expansion of Arabic people. 300 years later, in the 10th century, variola crept into Asia Minor and modern-day Portugal. During the Crusades in the 11th century, smallpox spread further throughout Europe and infect many more unsuspecting people. Smallpox spreads to northern England, which was previously not affected by this deadly disease. When Smallpox spread to Northern England, it caused multiple outbreaks that traveled as far north as Iceland. Smallpox at this point had already killed people from Egypt all the way to Northern Europe and was not stopping there. In the 15th-16th Century, smallpox was spread through Portuguese traders into Africa. European colonization and the African slave trade spread Variola

One of the 1st people to get smallpox was Pharaoh Ramses V. In the year of 1967 over 131,000 cases occurred from 42 countries. Now, no-one has smallpox.

The earliest indicator of smallpox in history is the extensive lesions on three Egyptian mummies. There are also recorded cases from the Hitties (1346 BC), Syracuse (595 BC), Athens (490 BC), China (48AD), Korean Peninsula (583 AD), and Japan (585 AD), however, they are not definite cases because these ancient physicians were unable to distinguish smallpox rashes from other skin rashes. Nevertheless, this distinction was made in 910 AD by physician Al-Razi. As Islam spread across North Africa and the Iberian Peninsula, smallpox followed. By 1000 AD, smallpox epidemics were widely recorded from Japan to Spain. In the 16th century, smallpox outbreaks hit large cities such as London and Geneva, and exploration across oceans facilitated the spread of smallpox as well to the Americas, Australia, and South Africa. In the Americas, natives were seen as lesser and put to work in mines and on plantations where the combination of poor working conditions and European disease thinned out their population. This encouraged the importation of slaves from Africa as replacements and eventual establishment of slave trade to the New World. Smallpox outbreaks killed many natives, starting in Hispaniola and spreading to Cuba, the Yucatan, and other parts of Mexico. The spread was almost systematic, and due to the nature of smallpox, affected isolated, indigenous populations. Even after Edward Jenner created a successful vaccine for smallpox, it remained a serious threat, as many people, especially in rural areas were not

Smallpox is a highly contagious infectious disease. The type of microbe for smallpox is the Variola virus. Smallpox is caused by either the Variola major or the Variola Minor. This virus is spread by direct contact. The disease was likely to be in human populations about 10,000 BC. An epidemic broke out in 1519 with the Aztecs and the Conquistadors in Tenochtitlan Mexico. The epidemic killed a total of twenty five percent of the Aztecs population leaving it easy for Cortes and the conquistadors to take over the desired

Smallpox is an acute contagious viral disease, with fever and pustules usually leaving permanent scars. Although there is no cure, there is a vaccine that can help protect you from it. It is called vaccinia and is a poxvirus closely related to the smallpox. Live vaccinia infects the people but it does not make them sick. A smallpox particle can either make or consist of around two hundred different types of protein. In the center of the mulberry of a smallpox particle, there is an odd shape that looks like a dumbbell, this is the

The earliest case of smallpox according to a journal published in the US National Library of Medicine titled, “Edward Jenner and the History of Smallpox and Vaccination” was recorded as early as 1122 BC. (Riedel “Smallpox the Origin of a Disease”). Mankind’s triumph over this horrible disease was initiated by an English doctor named Edward Jenner. Through observations and experimentation, Jenner would create a procedure now known as vaccination. (Riedel “Edward Jenner”). During the next two centuries, vaccinations would be used worldwide to stop the spread of small pox. After the successful worldwide vaccination campaign led by the World Health Organization, small pox was eradicated worldwide in 1980. As a result of the eradication of smallpox according