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Solid Pseudopapillary Neoplasm

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Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare cystic tumor that is endocrine in origin, therefore, typically found in the head and/or body of the pancreas. SPN constitutes about 1% of all pancreatic neoplasms, but advancements in diagnostic imaging have led to an increase in findings. Patients with SPN are usually asymptomatic and those with symptoms report generalized abdominal discomfort. Lab values used to evaluate the pancreas are usually within normal limits. Because these neoplasms are typically asymptomatic they grow undetected and masses in the head will produce symptoms associated with obstruction and pancreatitis. A 14 year old female with no known history of pancreatitis, alcoholism, diabetes, or biliary disease presented for an abdominal sonogram. Her only symptom was generalized upper abdominal pain with no history of nausea, vomiting, weight loss, or appetite changes. Ultrasound images showed a well circumscribed, round, hypoechoic 14-mm lesion within the head of the pancreas and another lesion in the body. Color Doppler analysis showed no internal or peripheral vascularity associated with the lesions. The main pancreatic duct was dilated, measuring at 4 mm. The ultrasound examination was followed by an MRI which demonstrated a 12 mm mass in the pancreatic body that correlated to the …show more content…

Characteristic findings include a well encapsulated mass with varying amounts of hemorrhage, necrosis and cystic changes, which allow for differentiation from other pancreatic neoplasms. The majority of SPNs are benign, but because of the chance of malignancy, the course of treatment is surgical resection of the tumor along with pancreatectomy, splenectomy or pancreatico-duodenectomy. Because sonography is becoming an initial imaging test to investigate vague abdominal pain, sonographers should be aware of SPN as a differential diagnosis, especially in young female

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