Essay on Some Fact About The Prolific Theories of Bone Growth Anatomy

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Today, there is an enormous amount of understanding of the anatomy of bone formation than it was available to Duhamel du Monceau and John Hunter when they made the then prolific theories of bone growth anatomy. Duhamel proved, in 1742, that the bone is first formed in the periosteum and grows in superposing layers. Hunter, through his experiments showed that bone grows in length by juxtaposing layers and the medullary cavity (Trabecular bone) grows by resorption of inner layers of bone. He also showed that the ends of the bones show remodeling via cycles of bone formation and resorption. Duhamel du Monceau used madder dye, an extract of the root of Rubia tincterium tree, in a staining technique that enabled him to show that bones…show more content…
Duhamel formulated experiments to study how bone grows, based on the analogy of a possible similarity between the healing of bone fractures and the repair of broken trees. He wrapped silver wire loops sub-periosteally around the cortex of young pigeons and noticed that the coil came to lie closer to the bone marrow cavity as growth continued. Duhamel used quite similar mechanical techniques for determining the circumference of the limb of a tree by wrapping an iron wire around it. Some years later, after sawing down the tree, he found that the hardened portion of the limb had not increased in size. Therefore Duhamel was able to observe the periosteal growth of bones based on the analogy of tree growth.

To study the longitudinal growth of a long bone, Duhamel inserted needles at equal intervals into the femur of a newly-hatched chick. Dissection of the femur of the chick, fifteen days later, revealed the impressions made by the needles to be separated by various intervals, smallest nearest the trabecular region and largest nearest the cortical bone because hardening begins in the trabecular of the bone and gradually proceeds towards the cortical bone. This proved that the different portions of the bone do not all grow equally but the trabecular bone grow more than the cortical bone. This phenomenon is now known as longitudinal bone growth.
Today, there is an enormous amount of understanding of the anatomy of bone formation than it was available
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