Speech Amyotrophic Lateral Disease : Is A Chronic And Terminal Disease That Affects The Lower And Upper Motor Neurons

I. Take a moment, and point at the computer screen. Notice that your index finger is extended and your other fingers are curled into your palm. How did your hand know to do that? It all began in your brain, the starting point for an important chain of communication. Your brain ordered nerve cells, to activate

Have you ever heard of ALS, better known as Lou Gehrig’s disease? For many people, ALS is a disorder that they may not know much about. I never heard of it either until my father was diagnosed with this disease in 2006. Because there is no known cure, it is important to detect this disease early, so that proper treatments and preparation can be done before it’s too late.

Following the diagnosis of ALS the main goal of treatment is focused at relieving the symptoms. The most important matter in managing ALS patients is that they continually sustain the highest amount of movement and activity as possible and remain comfortable while doing so. Although a cure for ALS has not yet been developed, effective treatments do exist to assist the patients in their fight with the disease. Physicians urge the patients to carry on with their everyday lives doing all the activities and physically exerting themselves as they would normally do. But, they also recommend the patients to limit their amount of physical exertion

Als which is an acronym for Amyotrophic lateral sclerosis has gained a lot of fame due to the Fundraiser “Als Ice Bucket Challenge”. Many celebrities, famous athletes and everyday people have participated in it and in doing so they have raised a substantial amount of money for research. Although, many people are still left wondering what exactly Als even is. Then, there are the people who know all too well about Als and those people are the sports world. Along with Als he’s Malicious relative Cte is not far behind getting the attention of many people as well. Cte stands for Chronic Traumatic Encephalopathy it is a degenerative disease found in the brain. They are both Gruesome Diseases that have many people wondering “how can i protect myself”.

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease affecting both the upper and lower motor neurons in the cerebral cortex, brainstem, and spinal cord. It is the most common motor neuron disease in the adult population with a prevalence of two to seven cases per 100,000 individuals. Survival rates in persons with ALS show considerable variation. Five-year survival rates vary from 7% to 40%, whereas 10-year survival rates range from 8% to 16% (cite).

Throughout this time one has heard about strange diseases that have a huge affect on people. There is a mystery for this happening. Amyotrophic Lateral Sclerosis (ALS), Chronic Traumatic Encephalopathy(CTE), Huntington's Disease, Parkinson’s Disease, Dementia, and Alzheimer’s have the something in common, the brain. Although one intends to think it can handle pain, but failing to not being treated or failing to rest this impact will have bad results. If one only doubts, it will not have anything happen to that particular person, that person can think again. This may not happen today or tomorrow, but it can happen to to one later on throughout that person's lifetime if it is chosen to ignore all this. Some of these diseases have not been

the U.S. today. One in 50,000 people will be affected in any one year. The

Throughout history there have been an array of diseases and illnesses, everything from the common cold to epidemics that have decimated populations. Medical Science has progressed to the point that many diseases are now treatable, curable, or even extinct. Yet even with this incredible progress there are still many diseases that remain not only without a cure, but without even effective treatments. One of these diseases is amyotrophic lateral sclerosis. ALS, or Lou Gehrig’s disease as it is commonly known, is a degenerative disease affecting the nervous system and the only outcome is death.

Amyotrophic lateral sclerosis, or ALS, is a neurodegenerative disease associated with the breakdown and loss of motor neurons in the brain and spinal cord. Voluntary muscle control degenerates until the body eventually loses function. To better understand how ALS works, the medical terminology can first be translated into a more basic understanding. ‘A-’ meaning not, “myo-” meaning muscle, and “-trophic” meaning nourishment or growth [source]. Due to the loss of motor neurons, the muscle loses nourishment and atrophies, or wastes away. “Lateral” means that this condition usually affects only one side of the body and “sclerosis” means hardening and buildup of fibrous (scar) tissue. The disease is progressive and is 100% fatal.

Amyotrophic Lateral Sclerosis (ALS) has been heard of at some point whether it was studied in school, talked about through word of mouth, or one decided to partake in the ALS Ice Bucket Challenge that swept the internet recently in support of the disease. This paper is going to delve into explaining the manifestations of this disease, its treatment and talk about the man this disease was named after.

Amyotrophic Lateral Sclerosis, more commonly know as ALS or “Lou Gehrig's Disease”, affects the nerves in the brain and the spinal cord. ALS is a disease of the nerve cells in the brain and in the spinal cord that control muscle movement. Over 5,600 people in the United States are diagnosed with ALS a year and about 30,000 Americans have ALS at a time. Some symptoms or signs of ALS are people’s arms and legs beginning to lose strength and muscles could become tight. Also, feet and ankles may develop weakness. General fatigue may develop and some muscles, like tongues, may twitch. Additionally, swallowing, speaking, and breathing may become harder to do. People with ALS may have slow eye movements and their

Neurodegenerative diseases is an umbrella term used to describe diseases of the nervous systems that result in the degradation of neurons in the brain and or spinal cord (CITATION). In the case of Amyotrophic Lateral Sclerosis (ALS) the body’s motor neurons die in the motor cortex, brain steam and spinal cord because the brain can no longer send signals from the brain to the muscles. Leaving the individuals on a rapid progressive decline in motor function, which ultimately ends in death as a result of the loss of the muscles (paralysis) that preform breathing and coughing and or other respiratory complications that result in death (Redler & Dokholyan, 2012). ALS was first noted in 1869 by a French neurologist named Jean –Martin Charcot

A distinctive characteristic of ALS is that although the motor neurons die, the brain, cognitive functions and sensory neurons stay intact (Porth & Matfin, 2009). This makes the disease especially devastating because patients become trapped inside their dying body, with a fully alert mind, but are unable to move. It is not known what causes the exact death of the motor neurons in the body, but “five percent to 10% of cases are familial; the others are believed to be sporadic” (Porth & Matfin, 2009, p.

Parkinson’s disease, Lou Gehrig’s disease, Sickle Cell Anemia, Alzheimer’s. This world is plague by countless diseases and there existed a time where, after many failed research attempts, scientists began to believe that people would always suffer from these diseases. However, with the introduction of stem cell research those past notions were dismissed. Upon their introduction, stem cell’s provided a new hope to the world and it proved itself to be an invaluable asset. Through stem cell research, a multitude of cures have been brought upon the world and these diseases that were uncontrollable in the past, can now be regulated and the ones suffering from now have a chance at living a better life. Sadly, there are many people who

ALS disease often manifests in early adulthood and is associated with loss of motor neurons in the cortex , spinal cord, and brainstem [44, 45]. ALS leads to progressive weakness of autonomic muscles. Death typically results due diaphragmatic failure within 2–5 years. Sporadic type of this disorder is prevalent and the incidence rate of hereditary forms of ALS is accounted for 5 to 10 percent of patients. Hereditary ALS could result by infusions in sarcoma (FUS), superoxide dismutase 1 (SOD1), TAR DNA-binding protein 43 (TDP-43), and C9ORF72 mutations. SOD1 mutation solely account for ~2% of ALS patients. Pig models have been created which