Spinal Cord Injury Research Paper

(THIS WAS AN INFORMATIVE SPEECH I DID FOR MY COM220 CLASS ON THE STAGES OF SPINAL CORD INJURY RESEARCH. IT ACTED AS AN INTRODUCTION TO MY PERSUASIVE SPEECH ON THE BENEFITS OF STEM CELL RESEARCH)

Football is known as the most popular sport in America. But, little people know about the “Silent Killer.” Football injuries are all too common, one of which being Spinal Cord Injuries. Nobody understands how devastating Spinal Cord Injuries can actually be, until it’s too late.

Although these models were reported to produce graded severities of brain injury with similar morphology to the clinical condition, they present their own limitation. The severity of injury induced by an acceleration injury (weight drop) is often highly variable. Mild CCI cause focal contusion and subrachnoid hemorrhage are not commensurate with the typical concussion in humans. CCI and FPI require craniotomy/ craniectomy which are not clinically relevant. While blast injury is more controversial model with little standardization in blast modeling with regard to the duration of exposure and measurement of peak overpressure. An updated concussive animal model is necessary to replicate the important features of the injury in patients with mTBI as closely as

Before we determine how stem cells can treat various diseases including spinal cord injuries, let us first

King will be talking about how dangerous football is. There will be knee cartilagae tears. I will also be talking about spine injuries. The final thing is death. Thatnis all.

The central nervous system is what connects the brain to the muscles of the body. When a patient has an injury to the spinal cord, movements in certain parts of the body will be affected based on the location of the injury. If the injury affects hand motion then many day to day tasks are affected. This literature review seeks to understand how an injury to the spinal cord impacts movement, and what has been done so far to help those affected by spinal cord injuries.

Spinal cord injuries can be extremely debilitating with significant impairment in autonomic, sensory, and motor function (Coll-Miro et al., 2016). The prevalence in Canada is on the rise with approximately 86,000 individuals suffering from such injuries as of 2010 (Noonan et al., 2012). Spinal cord injuries are generally classified as either traumatic or non-traumatic, depending on etiology (Sabapathy et al., 2015). In addition, they are subdivided into either complete or incomplete, depending on whether the spinal cord section is fully or partially damaged (Wilberger and Dupre, 2015). The latter classification has better clinical outcomes as some neurologic function is reserved (Wilberger and Dupre, 2015). Other subtypes include paraplegia and quadriplegia denoting paralysis of the lower body or all limbs, respectively (Wilberger and Dupre, 2015; Mayo Clinic Staff, 2014). The pathogenesis of spinal cord injuries is characterized by primary tissue damage due to the force of impact, followed by secondary tissue damage as a result of the inflammatory response (Sabapathy et al., 2015; Coll-Miro et al., 2015). The symptoms and severity may vary depending on the location and pathology of the contusion (Sabapathy et al., 2015). Presenting symptoms include but are not limited to numbness or pain in the extremities, loss of sensation, impaired movement or gait, abnormal reflexes, disrupted bladder or bowel function, and sexual dysfunction (Mayo Clinic Staff, 2014). Several

The central nervous system is responsible for controlling involuntary actions such as respiratory rhythm and blinking as well as voluntary actions such as muscular movements like walking. The central nervous system is composed of neurons that send and receive chemical messages through the transmittance of neurotransmitters. The spinal cord connects the brain to the body and when the spinal cord is damaged it loses its function to communicate messages from the brain throughout the body. Depending on the location and severity of the injury different symptoms and pathologies occur. There are different ways in which the spinal cord can be injured. It is protected by the spinal column, which is also called the backbone or spine. The spinal column is composed of a chain of bones called vertebrae, which are interconnected by flexible ligaments and spinal discs. However, if the spinal cord in injured and it starts to swell it starts to create pressure because the spinal column is surrounding it. Fractured bones of the spinal column or herniated discs can also cause damage to the spinal cord. The most common type of injury to the spinal cord is spinal cord compression when it is compressed due to a force on the spinal column. All of these different types of injuries lead to cell degeneration and death of the different types of cells in the spinal cord (Badner et al.

Although the physiology and function is somewhat different in rodents and human spinal cords there are many biological functions that are conserved in vertebrate animals (2). In many spinal cord injuries, rat models are employed to study cell death, inflammation, and regeneration (2). In surgical modeling, recapitulating the physiology is important to insure surgical techniques can be employed across species. Non-human primates contain spinal cords that are more like humans due to closer evolutionary distance (3). Using both model organisms can help to answer questions on the cellular level as well as the macroscopic concept of

The brain, spinal cord, and nerves which make up the nervous system is a very complex system. One of the many differences which makes the nervous system more special than the other systems is that it extends throughout the whole body. it makes us sense by sending signals from one cell to another. The brain by itself is amazing and intriguing, but sometimes the problems that happen to the brain can be much more interesting. When a part of the brain fails or dies, or even change, it can change the whole life of a human being. For instance, let us look at psychopathy. psychopaths lack empathy, remorse and many other things. A lot of people think that sociopaths want to be cruel, which is not the case. it just that the part of the brain that involves emotion is dead. So what happens to the brain when one

The limited space within the vertebrae actually plays an important roll in spinal cord injury. Once the initial injury occurs the body, as with every other part of the body, tries to protect the injured area with swelling. But the swelling occurs within the small confines of the spinal column and causes further damage to the surrounding tissue. It has only recently been discovered how much of an impact this secondary damage has. One of the areas of crucial ongoing research is on what kind of window of opportunity medicine has in treating these types of injuries and still attaining the best recovery.

Spinal cord injuries result from a fracture or dislocation of the vertebrae that is typically due to a sudden, forceful blow to the spine (“NINDS Spinal Cord Injury Information Page”, 2016). According to Early (2006), A traumatic accident, such as a shooting, stabbing, car accident, or diving accident, may result in a spinal cord injury (p. 535). According to the National Institute of Neurological Disorders and Stroke (2016), Damage to the spinal tissue results from displaced or shards of vertebral bone fragments, damaged ligaments, or discs that bruise or tear the delicate tissue and destroy axons. Destruction of axons result in the inability to carry signals from the brain and spinal cord to the rest of the body (“NINDS Spinal Cord Injury

Furthermore, recent research has suggested biomarkers could be of assistance in preventing pressure ulcers in those patients who have suffered a traumatic spinal cord injury. As healthcare continues to advance, Oxy-Mat will work to improve their product using the new information obtained. They understand science plays a large role in determining the best options for patient care, thus they make certain they follow the news in the area of pressure ulcer prevention and treatment.

The spinal cord is a major channel in the body where motor and sensory information travels from the brain to the body. It has white matter that surrounds a central gray matter. The gray matter is where most of the neuronal cells are located. Injury to the spinal cord will affect the conduction of information across any part of the spinal cord where the damage is located (Maynard et al., 1997). This will often result in permanent disability of a certain muscle or region of the body (Meletis et al., 2008) and a loss of tissue where the damage is located (Peng et al., 2009). As of now, there is no treatment for spinal cord injury expect for steroids. All steroids can do is provide protect of the spinal cord from

Preventing a back injury is much easier than repairing one. Since your back is critically important to your ability to perform all daily activites including your job. Most pain arises from using your back improperly, so learning a few basic rules about lifting, posture and proper exercise can help keep your back in good