Stevens-Johnson Syndrome

Bipolar disorder is a complex mental health disorder that is characterized by recurrent episodes of elevated or irritable mood with variable states of depression (American Psychiatric Association, 2013). Patients suffering from bipolar disorder not taking any maintenance medications have been shown to have relapse rates of approximately 61%, leading to significant impairments in functioning and quality of life (Goodwin et al., 2004). Anticonvulsants used as mood stabilizers have become the main therapy for preventing relapse of mood episodes (Stahl, 2013). A major concern that has risen from the use of anticonvulsants as mood stabilizers is the propensity to develop a major dermatologic emergency: Stevens-Johnson syndrome (SJS). A seven-year study completed by Devi et al. (2005) concluded that anticonvulsants were the cause implicated most in SJS, especially in the first eight weeks of treatment, and the main drug responsible (more than 80%) was carbamazepine. Providers involved in the initial and maintenance prescription of anticonvulsants as mood stabilizers, or for any other designated use, should be knowledgeable of the risk for SJS associated with these medications, and the benefit of using these medications as indicated.

Danielle gave her son, Finley, a liquid dose of ibbuprofen. A few days later, she had to rush her son to the hospital. Finley struggled to breathe and developed a high fever. He also had blisters across his body. Danielle stated that she had no idea what was happening to her son. Finley's condition began to deteriorate in the hospital. His skin started to turn black and his organs started failing.

This reaction occurs as a result of the bodys immune sytem reacting innappropriately in response to substances

"For the majority of conditions, what you've inherited is a susceptibility to a disease or condition," Dr Barlow-Stewart says. "To happen they need a triggering factor and, although we don't know what all these factors are, there are some like smoking and poor diet that we do

Several predisposing factors were identified in S.P.’s medical history. She is at risk for infection due to her medications methotrexate and prednisone. The client is at risk for bleeding because of the new order for Lovenox and Coumadin (Orlicka, Barnes, & Culver, 2013). S.P.’s smoking history puts her at risk for anemia on top of her RA and surgery being a major risk for anemia.

In 1964 Dr. Robert Douglas Sweet introduce the Sweet syndrome or Acute Febrile Neutrophilic Dermatosis in the medical literature. The disorder is classified as a neutrophilic dermatosis, which is a general term for a group of skin disorders characterized by the accumulation of neutrophils in the skin. Neutrophils are a type of white blood cell that is important in fighting off infection by destroying bacteria that enter the body. In Sweet syndrome neutrophils accumulate in the dermis, the thick layer of tissue just below the outer layer of the skin .

JEB can be characterized by symptoms including fragile skin that results in blisters and skin erosion, and is prone to bacterial infections and skin cancers, such as squamous cell

Wernicke-Korsakoff syndrome is a neurological disorder. It happens when there is a lack of vitamin b1. It’s more common in those who are heavy drinkers due to the fact that those who drink often, usually have a lack of thiamine (vitamin b1). It can also occur in those who have other disorders such a malabsorbtion, cancer that goes through your body, AIDS, or extremely high thyroid levels. A severe lack of thiamine causes microscopic bleeding throughout the brain and causes scar tissue to develop.

Psoriasis is a constant immune system infection that for the most part influences the integumentary framework. In the United States, psoriasis is the most common immune system sicknesses, affecting around 7.5 million Americans, or 2 – 3% of the populace. Despite the fact that psoriasis can happen at any age, the mean period of onset for the first event is between 15 – 20 years, with a second crest at 55 – 60 years. While the definite reasons for psoriasis are obscure, the illness happens when a strange insusceptible reaction prompts hyperproliferation of youthful cells of the dermis and epidermis, changed cell separation, and aggravation. The invulnerable reaction connected with psoriasis is T-cell intervened. Lymphocytes will be lymphocytes, or

I. The system that is being attacked is the Lymphatic System. Samuel has edema or another word for this is lymphedema. Edema is a type of lymphatic obstruction or a blockage in lymph system. This is the medical term for swelling in this case it is the swelling or his lymph nodes and this is mostly in the arms and legs. The swelling he is having is coming from the lymphatic fluids that are not being taken back into the bloodstream. Since the Lymphatic system helps cleanse the blood and takes toxic wastes out of the body. Those cells are involved in immunity is why he is getting infections on his skin because the lymphatic system is not working right is making him get these infections. If the body is not taking out all of the

A rare and serious disease that is uncommonly associated with Sjögren's syndrome is primary biliary cirrhosis, an autoimmune disease of the liver that leads to scarring of the liver tissue.

Psoriasis is an irritating skin disease that primarily affects the scalp and extensor surfaces of the knees and elbows, though it can develop anywhere in the body. It is characterized by patches of abnormal skin that are typically red, itchy and scaly. It occurs when the reproduction of basal cells which are set at the bottom of several layers of cell and from which the skin growth increases dramatically. The upper layer of skin cannot shed the dead cells at the same rate and this scaly build-up occurs. The increase in basal cell production is believed to be caused by an imbalance of 2 natural chemical complexes called cAMP, which inhibits cell growth and cGMP which encourages cell growth. Proteins and toxins from bacterial and yeast metabolism

The Koebner phenomenon, i.e. the appearance of psoriatic lesions by Injury to the skin is observed in approximately 25% of patients with psoriasis. A particular patient may be “Koebner-negative” at one point in time and later become “Koebner-positive”. The Koebner phenomenon suggests that psoriasis is a systemic disease that can be triggered locally in the skin. Psoriatic lesions can also be induced by other traums as sunburn, drug eruption. The time taken between the trauma and the appearance of skin lesions is usually 2–6 weeks (Van de Kerkhof and Nestle, 2012).

Psoriasis is a common skin disorder affecting millions of people. It affects 2 to 3% of the Caucasian population, usually in individuals between 15 and 30 years old. (Liu, Krueger, & Bowcock, 2007). There are several different forms of the disease. The most common type is chronic plague psoriasis. It presents itself as silvery-scaled patches usually on the knees, elbows, lower back, and scalp. Outbreaks can be triggered by infection, such as strep throat, drug-use, psychological stress, hormonal changes and skin injury. The exact cause is still unknown; however, research has provided some interesting insights into the pathophysiology of psoriasis.

Skin is a largest organ in the body; it is the first and primary source of protection. When you meet someone new the one of the first thing one looks at is their face, their skin. Even trough most skin conditions are not deathly, they can cause s a significant morbidness and lower the quality of life. In addition, many skin condition can indirectly cause additional illnesses. The skin protection and health can become compromised due to environmental factors, or genetic mutations. When skin’s protection gets compromised the skin looses its balance and it manifest as: inflammation, redness, scaly, dry, and hypersenstative skin. Examples of genetic disorders that can cause such abnormalities in the skin are peeling skin syndrome, and porphyria.