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Subclinical Atherosclerosis In Children And Obesity Case Study

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4. Discussion
A degree of subclinical atherosclerosis in children and adolescents is related to obesity assessed by BMI [26, 27]. We previously reported that increased BMI is associated with increased cIMT, circulating levels of inflammation, and endothelial dysfunction and other CVD risk factors among schoolchildren aged 10-15 years [28]. The relationship between abdominal obesity and atherosclerosis development has been established among adults [17]. As such, atherosclerotic events could be avoided by preventing abdominal obesity [29]. Given that increased WC has been linked to an increased risk of cardiovascular events in children and in adults , WC has been used as surrogate markers to evaluate abdominal obesity; [20, 30]. Hence, the …show more content…

The findings of this study show an increase in both SBP and DBP among the HWC group as compared to the MWC and LWC groups. Increased blood pressure (BP) is common among obese children in comparison to non-obese children of all ages [34, 35]. Higher BP during childhood can be predictive of sustained hypertension in adulthood [34]. Waist circumference was more positively associated with blood pressure than other anthropometric measures among children [36]. The findings of the present study demonstrate that an increase in WC was correlated with increase in BP. Similar observations were observed in other reports. Duncan et al. [37] reported that WC was associated with hypertension in their cross sectional study that included 445 children and adolescents (10–17 years), in addition Flores-Huerta and colleagues [38] indicated that the prevalence of increased blood pressure and risk of its presenting were significantly higher when using WC than BMI in a sample of 2029 children and adolescents.
Our findings revealed that higher WC was significantly correlated with higher levels of TC, TG, LDL and lower levels of HDL. We found a significant correlation between dyslipidemia, and WC after adjusting for age and sex, moreover, significant associations between WC-SDS and HDL, and LDL were reported using multiple linear regression analysis after adjusting for BMI-SDS. Parallel

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