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Summary: Acquired Brain Injury

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TBI is defined as an acquired brain injury that occurs if the head is violently or suddenly struck causing damage to the brain (Shen et al., 2016). This injury may be focal or diffused, open or closed Skull injury depending on the type of causes (Blast, accident, sports related injury, violence) and severity (mild, moderate, severe). Brain injury resulted from external force causes macroscopic tissue damage at the time of injury and initiate cellular processes that evolve over hours and days. Generally, it takes less than 100 milliseconds to initiate the primary injury, which further results in prolonged and progressive pathophysiological events known as secondary injury, the later outcome of the biomolecular and physiological changes following
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