Summary: Direct To Consumer Genetic Testing

   The Human Genome Project is the largest scientific endeavor undertaken since the Manhattan Project, and, as with the Manhattan Project, the completion of the Human Genome Project has brought to surface many moral and ethical issues concerning the use of the knowledge gained from the project. Although genetic tests for certain diseases have been available for 15 years (Ridley, 1999), the completion of the Human Genome Project will certainly lead to an exponential increase in the number of genetic tests available. Therefore, before genetic testing becomes a routine part of a visit to a doctor's office, the two main questions at the heart of the controversy surrounding genetic testing must be

It is patients’ right to opt for genetic testing on their own DNA, although they are accepting a great risk by doing so.

Genetic testing has brought about many changes in the way many couples look at conceiving and raising families. Through genetic testing you are able to screen for the increased chance that a fetus may have one of many congenital disorders, or even identify gene changes that are responsible for a disease that has already been diagnosed (Genetic Testing, March 2015). Unfortunately genetic testing is not always exact, in some cases giving parents false negatives or false positive results. Even if the results are accurate, there is the burden of knowledge once you know the results indicate a genetic abnormality such as Down’s syndrome. While caring for a 2 year old male patient with developmental delays and anotia, I learned that genetic testing had been started but never completed on the child. Genetic testing could help to identify genetic disorders that led to the child’s developmental delays and possible future disorders that may develop. The ethical dilemma I will be discussing to the ANA Ethical dilemma of the impact of informed consent of genetic testing on children for adult onset diseases and disorders.

The records have been reviewed. The member is an adult female with a birth date of 05/12/1964. She has a diagnosis of early stage colon carcinoma. Her treating provider, Stephen Grabelsky, MD recommended the Oncotype DX Colon Cancer Assay.

In chapter four of her book Genetic Dilemmas, Dena Davis asserts that it is unethical for parents to subject their children to genetic testing for the markers of adult-onset genetic diseases because it places an unfair constraint on a child’s right to an open future. It both removes the child’s ability to choose whether to be tested as an adult and has the potential to negatively alter the overall trajectory of their lives. While the current consensus amongst medical professionals is that such testing should be prohibited (Davis, _____), many concerned parents correctly point out that discouraging such testing creates a conflict of interests between the “beneficence model of patient care and the rights of parents to their own autonomy”

The inclusion of genetic testing into Electronic Health Records impacts the overall healthcare of patient’s because it informs the physicians and other medical professionals the selection of effective treatment or preventive action. A manager’s responsibilities are to implement policies to protect the confidentiality, privacy, and security of genetic tests results and information of patient’s. Policies contributing to potential discrimination acts are also advised because genetic/genomic testing reveals a patient’s physical characteristics.

Patent Genes have been the center of a attention for a very long time. When we take the time to stop and think about how research and medical cost affect our lifestyles, it is very alarming to know that even the natural occurrences in life can be bought for the right price. In the op-ed piece and article, “Patenting Life” and “Decoding the Use of Gene Patents”, by Michael Crichton and John E. Calfee, both authors draw attention to the uses of patenting genes. Crichton goes on to say how gene patents have interfered with medical testings, research studies, and the miscommunications between doctors and their patients, while Calfee reiterates how patients and researchers are getting the benefits that come from patenting genes. Although both authors

As the number and availability of various genetic tests have grown, so too has a fear among Americans that their genetic information may be used for purposes other than curing or preventing diseases. This paper looks at the law Genetic Information Nondiscrimination Act passed in 2008 and how it influences the workplace and the health insurance practices.

If the genetic information is only accessible to the individual then there is a decreased chance of such discrimination occurring because the information is disclosed to who the individual wishes to. Genetic information can raise questions about personal responsibility, personal choice versus genetic determinism, and concepts of health and disease. Personal factors, family values, and community and cultural beliefs can mould the reactions to these issues. For example the response to the genetic information and suggestion from physicians after the test will be drastically different in a society where traditions and religion determine life choices, such as India, than to a more individually liberal society like the USA. Even in a progressive society that has had specific ethnic groups for multiple generations disparities with medical technology are common. A study conducted, using the national representative data, in the USA with the sample that consisted of 1724 men and women of non-Hispanic whites, Latinos, and African American background. Results exposed significant differences by racial/ethnic groups in knowledge and concerns about the potential misuse of genetic testing. Significantly higher levels of mistrust in a physician and the medical system was a common thread within minorities. The genetic tests can be a way of ridding anxiety attached to the assumed inheritance of genetic disease due to family background whilst for others the genetic test reveals their reality. The results can have a great deal of a psychological impact upon the individual. The possibility of developing a genetic disease alone can create anxiety within some. The psychological impact from the results revealed is another issue that society is concerned about. A

The Human Genome Project introduces significant scientific findings to the world, but raises a lot of controversies. Many of these controversies concern the application of this new scientific finding and its ethicality. Genetic information from a project, once aimed towards mapping the human genome in hope for curing diseases, are now being used in businesses. It shouldn’t be permissible for employers to require that all employees, as well as potential employees, be screened for genetic vulnerabilities and to use the results of such screening when they make hiring, retention, and job assignment decisions. These genetic vulnerabilities may include diseases, unsuitable personality traits and other traits the company deems undesirable. Employees shouldn’t be judged by their genes, because the results do not adequately speak for what the employees will do in life, the employee’s position in the society, and the employee’s financial standing. Genetic testing should be an option for the employees to decide on job assignment rather than influence the hiring decisions of employers. Genetic testing only shows genetic potential, not potential growth. Conducting genetic testings on employees infringes on their privacy and encourage more social gaps with genetic classes.

Although the gene chip will enable an individual to know whether he/she has a genetic disease, that person may not want to know the information. Many people are frightened that a positive finding on a genetic test will result in discrimination and ostracism because the society will consider them abnormal (Easthope 2005). The other concern is that with genetic test information one might lose or might be unable to get a job or insurance. There have been concerns that with the knowledge of one’s medical information after a gene test, he/she might suffer a psychological problem especially when the results reveal that one suffers from a terminal disease or has high possibility of suffering from one (Willis 2009).

Thousands of people are experiencing discrimination with insurance companies, over something they have no control over, their genes. Every person has multiple DNA differences/or genetic mutation that can increase and/or decrease their chance of acquiring certain diseases, such as: cancers, alzheimer's disease, diabetes, heart disease, etc. But just because people may have those certain genes/differences, does not mean that they will ever get that disease (Genetic Discrimination Fact Sheet, 2015). It is also discrimination because, if people are forced to show their genetic information, it will/can lead to vulnerable groups being denied insurance or will have higher premiums to pay. People cannot control their genes and they should not be subjected to this

Genetic information can be identified at any point throughout a person’s lifespan from pre-conception until after death. In addition to heritable, biological information, family history, genetic test results, and medical records are also sources of genetic information” (Jenkins & Lea, 2005). We are put in a position to gather and retain information that could be utilized for a better future, but is confidentiality involved for the sake of profiting? Ask yourself, who should have access to genetic information? Who owns and controls it? How can families resolve conflicts when some members want to be tested for a genetic disorder and others do not?

genetic testing, everything has changed. She notes that clinicians now have the ability to diagnose, treat, and monitor a patient’s illnesses or disease progression in an entirely different manner. This is a far cry from the old medical model of responding to a disease (or defect) only after it appears, and then prescribing the recommended medication or intervention. These genetic medical advances sound miraculous and promising, but the ability to test, screen and provide early intervention does not come without many major ethical dilemmas.

Genetic testing can be beneficial for individuals who want a better understanding of the risk for a specific disease, but if the genetic test is for a legal stance, its benefits can be questionable. For example, a man goes on a trial for a violent murder but his genetic test shows the defendant has a mutation in the monoamine oxidase A (MAOA) gene. His lawyer claims that due to the mutation in the MAOA gene, the man was not able to control his impulses that lead him to have the aggressive behavior. However, the lawyer’s argument could be putting a lot of emphasis on genetics and ignoring other phenomenons such as mutations and polymorphisms interacting with the environment that could exacerbate the elevated level of aggression. Thus, it is important to examine the result of mutation in the MAOA gene to determine the extent that the MAOA mutation is responsible for the defendant’s crimes rather than relying solely on MAOA test results to determine if the suspect is guilty.