Summary On The Importance Of The Work Of Griffith, Avery, Macleod, And Mccarty

Throughout the early 19th and 20th century, many scientists have studied deoxyribonucleic acids in order to attain higher understanding over the matter. Johann G. Mendel had figured out and understood the laws of heredity. Friedrich Miescher amazingly discovered DNA in 1869, even though scientists did not understand DNA was the genetic material

Walking to New York From Boston was when I thought that we would never win the battle against the British. I couldn’t believe that I was going to go to war with the British. The British had so much more experience than we did, There were some people who didn’t even have one bit of experience with weapons. Surely, I was nervous of going to battle. The whole time getting ready I thought about how much I’d miss my wife and are three children Lilia, beathanny, and Lucas. I thought to myself one day I won’t have to write to them, I can see them and tell them stories about the war. Right now all I need to think about is battling the British and surviving at the same time. When going to battle being intrepid we were

Chapter 1: Genes can be demonstrated as “instruction books for making functional markers such as ribonucleic acid(RNA) and proteins”(Chapter 1, page 4). Distinctively, the four nitrogenous bases to code the gene of DNA is adenine, thymine, guanine, and cytosine. In addition, Rosalind Franklin was among the primitive people to experiment with X rays as a form of molecular photography in order to learn more about DNA and its structure. The structure of DNA taught a constitutional fact about genetics; it stated that the two strands of DNA were complementary to each other. Moreover, DNA replicates in order to make new sets of

Later on through the works of Avery, Macleod, and McCarty in 1944, it became obvious that DNA is the transforming property and the substance

The field of biotechnology involves the concept of genetic engineering, altering the DNA/genetic material of an organism using information from a different one. The process in which bacteria can obtain this manipulated genetic information from another source is called genetic transformation. The goal of this experiment was to genetically transform Escherichia coli bacteria’s DNA by inserting the vector pGLO plasmid which codes for ampicillin resistance as well as the green fluorescent protein, GFP. For the experiment, the E. coli bacteria were separated into two groups; control and

It will also highlight how successfully integrated plasmids can affect the cell and what proteins are produced by the DNA, and how easy it is to change the genetics of cell and the future generations of that cell. The experiment also demonstrates how natural selection would work in a lab environment, and how the addition of a gene or a mutation can protect an organism from adverse conditions in the environment. This lab also illustrates the change in DNA in a visual sense. Molecular genetics is a very small scale science that cannot be seen by the human eye, however by illuminating the bacteria with the GFP it will produce the very small process can be clearly seen before and after the genetic splicing. The bacteria will produce quickly and the successful bacteria will be clearly seen by the human eye, even after generations upon generations of bacteria.

Scientist in early 1950s James Watson a biologist from Indiana University and Francis Crick a physicist were working at lab to discover the structure of DNA. The primary technique for structural analysis of biological molecules is X-rays. The wave length of X-ray is about the same as the space between the atoms in crystal matters. We learn and know that genetic information was carried on chromosomes made up of DNA and protein. Maurice decided and taken the first x-ray picture of DNA that lead him to suggest the DNA structure might be a helix. Watson was able to rely on Wilkins' research. If he had not, he may have not been the one to discover the structure of DNA. The biggest thing I learned from my research is that scientists can’t make discoveries

transformation and conjugation. The former would imply the presence of unknown transforming factors which brought about gene mutations that caused the reversion of mutant E.coli strain to wild type strain. The latter would then suggest that random gene reassortment in new combinations which required the fusion of bacterial cells in order to exchange genetic substances. Regrettably, no further evidences were produced to substantiate either one of these models.

DNA technology and advancements in technology in general, advancements in scientific discoveries and scientists who shared

3) Oswald Avery: Tested many strains of bacteria and discovered that DNA carries a cell’s genetic code and can be altered through transformations.

While he was researching, he began to study genes. It was thought at that time period that genes were made out of proteins and were able to duplicate themselves, hence the passing on of genes. DNA was considered nothing but a structural support for the proteins. But Watson was not sure of this. Watson read about the Avery-MacLeod-McCarty experiment, conducted by the people in the title, which implied that DNA was the genetic molecule. Watson later went to Copenhagen University for one year of postdoctoral research. At the university, biochemist Herman Kalckar wanted to use bacteriophages as an experimental system to study the synthesis of nucleic acids. Watson, on the other hand, wanted to see what was the structure of DNA. After some inconclusive experiments, he went to Italy. At Italy, Maurice Wilkins was giving a lecture about his X-ray diffraction of DNA. Afterward, Watson was now determined to find DNA's molecular structure. In 1951, Watson went to England at the Stazione Zoologica 'Anton Dohrn' in Naples to perform X-ray diffraction experiments. On 1953, using data from his experiments and other peoples' (some without

The origins of DNA were first discovered during 1857 by Gregor Mendel the "Father of Genetics”, whom was performing an experiment of genetics with pea plants, and would provide a basic foundation towards DNA and Genetics. Friedrich Miescher and Richard Altmann in 1869 were also part of the first people to discover DNA. While testing some sperm of a salmon, they discover a strange substance that they would name as "nuclein", which is known as DNA. This new form of "nuclein" (DNA) would be found to only exist in chromosomes. Frederick Griffith, a researcher, found the basis on DNA, from a molecule inheritance experiment involving mice and two types of pneumonia. His findings were that, when virulent disease is heated up (to kill) and is

The work of these four people led to a complete restructuring of the beliefs of the scientific community regarding genetic information. Their initial word led to further work which encompassed their hypothesis of how DNA replicates itself. From this work came the modern technologies of DNA fingerprinting and sequencing.

Avery, Macleod, and McCarthy took the findings of Griffith and wanted to reason why the combination of the two cells killed the mouse. The took the different parts which would cause the DNA, Protein, and RNA and eventually eliminated them one by one. After all of that, only bacteria that was exposed to the S-strain DNA were transformed. This gave the idea that DNA is what was controlling living things and was the outcome of this experiment

Bacterial transformation is the process of moving genes from a living thing to another with the help of a plasmid.The plasmid is able to help replicate the chromosomes by themselves; laboratories use these to aid in gene multiplication. Bacterial transformation is relevant in everyday lives due to the fact that almost all plasmids carry a bacterial origin of replication and an antibiotic resistance gene(“Addgene: Protocol - How to Do a Bacterial