Swertiamarin Lab Report

Compared to diabetic control rats, total antioxidant levels were significantly increased in GTE supplemented rats. Inversely, malondialdehyde levels and AT(1) receptor were significantly lower in the GTE supplemented diabetic group [77]. Catechin and its derivatives in green tea are shown to be therapeutically very effective.

According to Zimmet (2001), about 150 million people in the world have been suffering with diabetes and it would be 300 million by 2025. Another interesting study by AusDiab in 2000 revelead that 7.4% of the population aged 25 or over had diabetes (type 2 in 90%) Since 1981, the prevalence of type 2 diabetes has increased to twice in and the total number of cases has increased threefold in Australia (Dunstain 2002).Although type 2 diabetes is effecting all races,it was identified highly in south Asians and also worlds one-third diabetic population is from indian continent ( Jean 2008). According to the report from Centre for Disease Control and Prevention in United states of America, nearly 25.8 million people have been affected by diabetes in 2010 with 90- 95% of them being type 2 DM (CDC 2011). However, type 2 diabetes mellitus which is characterized by the deficiency and resistance of the

This indicates that the metabolism of proteins was apparently affected by Ch.t extract. The improvement on the levels of protein and albumin in the diabetic treated groups show that Ch.t extract have significant effect in glucose and protein level because insulin inhibit gluconeogenesis from protein [ ] or could be due to improvement in renal function. This affirmative agrees with the fact that the weight of skeletal muscles was significantly increase in diabetic rats treated with Ch.t extract. The decrease in albumin level documented for diabetic rats may be due to liver massive necrosis, deterioration of liver function, hepatic resistance to insulin and glycogen impairment of oxidative phosphorylation[ ].Under the same experimental conditions serum globulin level revealed an appreciable decrease[ ]. The renal pathogenesis is related to duration of diabetes, the most devastating complication with diabetes is nephropathy[

In summation, diabetes is a constant battle with no end. In this current time, diabetes can only be treated but cannot be cured. Diabetes is not a simple disease as there are two types. The two type of diabetes are type 1 and type 2. They both affect two different age groups in the population. Type 1 affects the adolescence and type 2 affects adults in their late years. As with many diseases, the understanding of diabetes is continuous but many factors are known as how diabetes occurs in the body. With such understanding, diagnosis of diabetes is able to be done properly and the right type of diabetes is also established. By way of diagnosis, the right treatment can be

Beta- carotene is an organic compound categorized as a terpenoid (Gutiérrez, & Gonzalez, 2010). Naturally, it is a predecessor of vitamin A, and found in several yellow fruits and vegetables. These organic nutrients play a vital role in aiding vision, skin growth, and bone development. In addition to these crucial roles, Beta-carotene may be of significant help in regulating the blood sugar in diabetic persons (Gutiérrez, & Gonzalez, 2010). Human bodies regulate blood sugar levels with the help of the hormone called insulin. In the absence or inadequate supply of this hormone, an individual is said to be diabetic. Diabetes may results in solemn conditions such as blindness, heart diseases, and stroke. Over the years, medical

These types of statistics, portraying the growth of diabetes diagnoses, have driven researchers and physicians to find diets, medications, and preventive measures for the disease. In reviewing the medications that are used to treat diabetes, their sometimes-severe complications should be noted. What’s more, none of them speak to the actual, principal source of developing diabetes. Therefore, research on preventive measures and diets have become popular.

Type 2 diabetes is considered as the most common form of diabetes affecting many individuals. This is a condition that is associated with a high buildup of sugar content in the blood stream. It is accompanied by symptoms such as constant hunger, fatigue, lack of energy and frequent urination. At milder levels, the symptoms become severe and lead to the death of an individual. In the United States, it has been rated as one of the leading causes of death. Importantly, it also increases the rate of the cardiovascular disease once an individual has been reported to have such symptoms. The cardiovascular diseases lead to a greater rate of complications in patients with type two diabetes and hence loss of life. Due to this reason, researchers have focused more on the development of appropriate drugs to enhance treatment of the condition. Importantly, the fact that it is a big challenge to the medical sector critical evaluation of all possible types of treatment is vital. Therefore, the article on “semaglutide and cardiovascular outcomes in patients with type 2 diabetes” offers beneficial knowledge to the healthcare sector.

Diabetes mellitus, commonly known as diabetes, is a metabolic disorder characterized by chronic high blood sugar levels. It is caused by an absolute or functional deficiency of circulating insulin, resulting in an inability to transfer glucose from the bloodstream into tissues where it is needed as fuel (Ahmed, Laing and Yates 2011). The disruption in the metabolism of carbohydrates, fats and proteins interferes with the secretion or action of insulin, which plays a vital role in the metabolism and utilization of energy from the nutrients especially carbohydrates. Insulin is produced in the pancreas and secreted in the gastrointestinal tract in the response to high blood sugar levels after ingestion of a substance (REFERENCE).

The discussion revealed that diabetic mellitus and diabetic foot ulcer affects the people with increasing age, sex, occupation, type of food consumption, economic condition, hereditary factors, history of diabetes etc. The economic burden on the patient with DFU needs to be eliminated. There is urgent need for alternative management of diabetes and DFU with herbal formulation.

How did the experts treat diabetes before they found the insulin? There are different remedial plants that are greatly extraordinary as against diabetic pros, with respect to occurrence beans and an expansive number of them have been starting now used as a part of the standard solution.

Reactive hypoglycemia, a rare form of hypoglycemia, increases insulin levels after the consumption of excess carbohydrates, leading to a drop in blood glucose levels. This differs from conventional hypoglycemia where blood glucose drops several hours after a meal, but can easily be returned to normal by the consumption of food. Reactive hypoglycemia can cause fatigue, dizziness, shakiness, and in extreme cases, a coma. Although no effective treatments exist, glucagon, a peptide hormone derived from pancreatic alpha cells, seems to reduce symptoms. In the proposed experiment, the effectiveness of glucagon relative to a regimen of dietary control, exercise, and Acarbose will be tested on Zucker-diabetic-fatty (ZDF) rats (Rattus rattus). Three

The use of traditional medicine among people in the worldwide and prescription of herbal medicine along with conventional medicine, has caused it was important in the recent years (36) therefor, the use of Lycium barbarium could be considered as an alternative treatment in order to decrease of blood glucose level in diabetes.

Lo C, Toyama T, Hirakawa Y, Jun M, Cass A, Hawley C, Pilemore H, Badev SV, Percovic V, Zoungas S. Insuline & Glucose lowering agents for treating people with diabetics and chronic Kidney disease. Cochrane Database of systematic reviews 2015, Issue 8. Art. No. CD011798. DOI:10.1002/14651858.CD011798.

Diabetes Mellitus is “a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. It is a disease which is caused by the insufficient insulin secretion or decrease in the peripheral effects of insulin. It is a serious problem in terms of morbidity and mortality. The hyperglycemia is associated with long term damage, dysfunction and failure of various organs especially the eyes, kidneys, nerves, heart and blood vessels. It’s associated with many complications which includes blindness of the eyes and amputations of the extremities. It is also associated with neuropathy, retinopathy, and cardiovascular diseases which lead to mortalities.

Herbal medicines are great alternative for commercially manufactured medicines available in the market. The major reason why herbal medicine differ from modern medicine is because they are produced with 100% natural content. Therefore the plant extract has all the medicinal values that are as effective as modern medicine. Commercially prepared drugs show results quickly but have numerous side effects. However herbal medicines don’t show any side