Symptoms And Subsequent Separation Of An Articular Cartilage Segment

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Introduction Osteochondritis Dissecans (OCD) refers to the death of subchondral bone and the subsequent separation of an articular cartilage segment.1 In Juvenile OCD, lesion are found in skeletally immature children (whose growth plate have not yet closed) usually occurring between the ages of 10 and 20.1 It is more commonly found in males, especially in those who are active and involved in organized sports.1 Pathogenesis The exact etiology is unclear.1 Ischemia, genetic predisposition, and endocrine issues have all been proposed to be involved in OCD pathology.1 Some suggest that two types of OCD exists, familial and sporadic.2 Familial OCD is a genetic condition that affects the joints all around the body and is associated with abnormal cartilage.2 Sporadic osteochondritis dissecans is associated with a single lesion in one joint.2 Knee OCD, the type most commonly found in the juvenile population is usually located on the lateral aspect of the medial femoral condyle.3 The location is commonly a site of repetitive microtrauma, this can indicate that trauma may play an important role in OCD development.3 The developmental sequence of OCD begins when articular cartilage detaches from the subchondral bone.4 The separation may spontaneously heal, or it may progress to a complete separation from the underlying bone.4 Once the separation is complete, a piece may break free and form a loose body within the joint.4 Interestingly, the particular material contained within the

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