Symptoms And Symptoms Of Multiple Sclerosis

Multiple sclerosis (MS) involves an autoimmune process that develops when a previous viral insult to the nervous system has occurred in a genetically susceptible individual. B lymphocytes, plasma cells, and activated T cells, along with proinflammatory cytokines, cause inflammation, oligodendrocyte injury and demyelination. Early inflammation and demyelination lead to irreversible axonal

This essay will look at Multiple Sclerosis and the impact that this health condition has on the physical and psychological wellbeing of an individual.

This report will discuss what multiple sclerosis is, symptoms, how it is treated, and much more.

Multiple Sclerosis (MS) is a neurologic disease that affects the Central Nervous System (CNS) through cellular immune response and the demyelination of CNS white matter (McCance et al., 2014, pp. 630–633). The initial causes of MS are unknown however, it is believed that it could possibly be due to an immune response to an initiating infection or an autoimmune response to CNS antigens on the myelin itself (Brück, 2005) (Miljković and Spasojević, 2013). MS is a result of the degradation of the myelin sheath surrounding neurons and therefore disrupts the transmission of action potentials along these cells. MS can display itself in the form of symptoms ranging from muscle weakness to trouble with sensation and coordination (NHS, 2016). The degradation of myelin leads the body to attempt to remyelinate the neurons, a process that in turn leads to the thickening of the cell by glial cells and this causes lesions to form (Chari, 2007). It is this thickening (sclerae) from which the disease gets its name. Sufferers of MS can either have a relapsing type of MS, in which there are episodes that lead to the worsening of symptoms for a period of time, or a progressive type of MS where symptoms gradually progress and worsen (McCance et al., 2014, pp. 630–633).

Multiple Sclerosis is a disease that attacks the myelin coating over the nerve receptors in your brain and spinal cord. Myelin is a fatty material that coats and protects the nerves in your brain. These nerves send signals to the rest of your body enabling

Multiple sclerosis is characterized by inflammation, demyelination, and axonal damage in the brain and spinal cord with a loss of myelin that covers the axons. As the myelin sheath regenerates, scar tissue forms, which looks like plaques on magnetic resonance imaging scans. Multiple sclerosis arises when immune-mediated inflammation activates T cells and causes the T cells and immune mediators to cross the blood-brain barriers into the CNS and attack oligodendrocytes (ie, a type of neuroglial cell with dendritic projections that coil around axons of neural cells). When the oligodendrocytes are attacked, the myelin sheath is replaced by scar tissue, which forms throughout the CNS. As a result of damage to the myelin sheath, the ability to transmit and conduct nerve impulses along the spinal cord and in the brain is interrupted, leading to muscle weakness, fatigue, loss of coordination, balance impairment, and cognitive and visual disturbance (DeLuca & Nocentini, 2011). This disease is characterized by unpredictable remissions that occur over several years. During periods of remission, the myelin sheath usually regenerates and symptoms may resolve, but the myelin cannot be completely repaired. As the disease progresses, the myelin sheath is destroyed and nerve impulses become much slower or absent and symptoms worsen. When degeneration exceeds self-repair ability, permanent disability results. There are four defined clinical types of

Multiple Sclerosis is a degenerative disease that effects the Central Nervous System. Approximately 400,000 individuals are living with Multiple Sclerosis in the United States, and 2.5 million worldwide. There are an estimated 10,000 new cases annually, in the United States alone. Various factors including geography, gender, and race are significant risk factors in developing the disease. Diagnosis at early onset of symptoms is beneficial to the treatment of progression and there are numerous medications used to combat the frequency and duration of relapse symptoms caused by Multiple

As of today, there is not a cure for Multiple Sclerosis, but the goal of treatment is to avoid any sort of neurological impairment (Ruto, 2013). Drugs can be used to help treat MS such as corticosteroids which help decrease inflammation and are frequently used by MS patients (Medical News Today, 2012). Other types of drugs that are used in treating Multiple Sclerosis are interferon’s to slow down the progression of the symptoms, copaxone to help end the attack of the myelin and mitoxantrone which help to protect the patient’s independence and decelerate the progression of disability (Medical News Today, 2012). Living with MS can be stressful, so having support groups can be helpful by sharing feelings and experiences

Multiple Sclerosis (MS). In the United States alone, approximately 200 new cases of MS are

Multiple Sclerosis (MS), is considered to be "a immune-mediated disease" (nationalmssociety.org). This means within the Central Nervous System (CNS), the immune system mistakenly attacks myelin – The "fatty substance that surrounds and insulates the nerve fibers" (nationalmssociety.org) – as well as nerve fibers themselves. When the myelin and nerve fibers are damaged, the myelin interferes with nerve conduction. The symptoms of MS relate to this interruption of signaling between

Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord, particularly the central nervous system (CNS). In MS the immune system attacks the myelin, which is the protective sheath that covers the nerve fibers and causes communication between your brain and the rest of your body. Eventually, the disease can cause the nerves to deteriorate or even lead to permanent damage. They deteriorate in variable degrees and produce significant disability within 20-25 years in more than 30% of patients, (Luzzio, 2016). The majority of people diagnosed with MS are adults between the ages of 20 and 45; twice as many women are affected compared to men. However, MS can present itself in childhood or late middle age, but is uncommon. According to Goldenberg (2012), there is no known cause for this debilitating disease, but it appears to involve a combination of genetic susceptibility and a nongenetic trigger, such as a virus, metabolism, or environmental factors

Individuals suffering from MS face continually worsening symptoms leading to progressing disability and early mortality. There is currently no cure and current treatments have negative impacts on the life of the individual receiving the treatment. The story of the discovery and understanding of the disease spans to almost two centuries of medical research and still there is much to understand. Autoimmune disorders are becoming more common in our society and it is crucial to understand the cause of these diseases and to develop better treatments. In the two centuries of research, the life expectancy of an individual with MS has increased dramatically. Upon diagnosis in the late 1800's and early 1900's individuals had an average life span of 10 years but today, due to advances in medical technologies, individuals with MS may live 30 years or more. More research is required to understand how to better treat this disease or prevent the initial autoimmune response from

Multiple sclerosis (MS) is an acquired demyelinating disease of the central nervous system (CNS) that typically is diagnosed in the second or third decade of life. Normally, nerves are enclosed in myelin sheaths that help facilitate transmission of nerve impulses within the CNS and the peripheral nervous system throughout the body. In patients with MS, the myelin sheath is damaged and eventually degenerates, causing patches of scar tissue called plaques or lesions to occur anywhere randomly on the myelin sheath (Ruto, 2013). This results in impaired nerve conductivity, which interferes with message transmission between the brain and the other parts of the body. As a result, impulse transmission is altered, distorted, short-circuited, or completely absent. This interference in impulse transmission creates muscle weakness, muscle imbalance, and possibly muscle spasms with partial or complete paralysis. Multiple sclerosis also can result in visual impairment and alteration of cognitive abilities, as well as pain, numbness, or tingling sensations (Ruto, 2013).

Multiple Sclerosis is a chronic autoimmune disease that attacks a person Central Nervous System which includes the spinal cord, brain and optic nerves. MS is a very difficult condition to diagnose due to its exacerbations. It also is difficult to treat because no one person has the same signs and symptoms. In MS the myelin sheath that protects the CNS becomes inflamed and scarred that end up causing lesions.. The lesions cause interruption in the messages to the nerves. MS can happen at any age but mostly found in ages 15-60 and are twice as likely in women. Currently there is no known cure for MS , researchers are working tirelessly to find one.

Multiple Sclerosis is a disabling autoimmune disease that basically attacks the protective sheath of our myelin. The myelin surrounds the nerve fibers and helps orchestrate impulses that our sent to our spinal cord and brain otherwise known as the central nervous system. People who are diagnosed with MS have damaged or inflamed myelin around the nerves causing poor conduction where the impulses are either weakened or lost. With the damaged myelin protective coating, the nerves are then more vulnerable to attack from the immune cells. As we know, immune cells protect the body from foreign substances such as bacteria or viruses. This neurological disease typically manifests in young people between the ages of 20-40 years old. MS is predominately diagnosed in woman more than men and also in Caucasians verses any other races. MS not only affects our ability to walk and talk, but our breathing even relies on proper functioning of the CNS. This disease deteriorates our myelin and is irreversible. Some people diagnosed with MS go long periods in remission while others eventually die.