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Symptoms And Treatment Of Crohn ' S

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VULVAR CROHN`S IN A PREPUBERTAL GIRL ON INFLIXIMAB Key words Vulvar Crohn`s. Crohn`s disease. Infliximab. Pre pubertal girls. Abstract Crohn`s disease is an inflammatory bowel disease. It often manifests as chronic diarrhea, abdominal pain, weight loss and blood in the stool. It usually involves any part of the gastrointestinal tract and sometimes presents with extra intestinal manifestations like uveitis, dermatitis, arthritis and anemia. Extra intestinal findings like Vulvar lesions are less commonly seen and even more rarely seen in pre pubertal girls. Vulvar Crohn`s can present as labial swelling initially and lead to ulcer formation, if not treated promptly. Crohn`s is treated with aminosalicylates, glucocorticoids and Infliximab (IFX) as induction therapy and aminosalicylates, glucocorticoids, antibiotics, methotrexate, IFX and Azathioprine as maintenance therapy. We present a 10 year old girl who presented with Vulvar Crohn`s while being treated with IFX for Crohn`s disease of the rectum and perianal area over a period of more than two years. Introduction Extra intestinal manifestations of Crohn`s disease (CD) could affect up to 35% of patients (1). Over 50% of patients with CD are women(2) and gynecological involvement of CD, besides fistulas arising from gastrointestinal tract, were already mentioned in the first reports of cutaneous CD in 1965(3) Vulvar CD is a rare condition, with 101 cases reported since 1965(4). It can also be seen in pre pubertal girls like

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