The term comorbidity refers to the association of two distinct diseases in the same individual at a rate higher than expected by chance (Bonavita and De Simone, 2008).
Although psoriasis has been previously thought to be a disease solely affecting primarily the skin and the joints, our understanding of the comorbidities that may be associated with this disease has grown significantly. Recent evidence has even suggested an increased over all risk of mortality in patients with severe psoriasis (Gelfand JM et al., 2007).
The presence of comorbidities in dermatology is of interest for various reasons. A skin disease can be an early marker of systemic disease, and therefore, identify patients who are at risk of having other, more
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A study by Cohen et al. (2008), supported previous reports of an association between psoriasis and diabetes mellitus. The age-adjusted proportion of diabetes was found to be significantly higher in psoriasis patients as compared to the control group. A possible explanation for the association between psoriasis and diabetes is the presence of chronic inflammation that occurs due to secretion of TNF-a and other proinflammatory cytokines such as IL-1 and IL-6, which precipitate both psoriasis and diabetes.
2) Non-Alcoholic Fat Liver Disease (NAFLD)
Prevalence of NAFLD in patients with psoriasis ran¬ges from 17-60% and is even greater in patients with severe psoriasis and PsA ( Miele et al., 2009) .Similarly, Gisondi et al. speculated that NAFLD may contribute to the seve-rity of psoriasis through the release of inflammatory mediators from the liver, including reactive oxygen species, CRP and IL-6, which also act as mediators of atherogenesis (Gisondi et al., 2009),Moreover, patients with psoriasis and NAFLD have higher risk of developing non-alcoholic steatohepatitis (NASH) and cirrhosis than patients with NAFLD without psoriasis (Wenk et al., 2009). At least in part, progres¬sion of NAFLD to NASH is associated with an increa¬se in the TNFa/adiponectin ratio. (Sanz Lp , 2007).
3) Depression and health-related quality of life (HRQoL) A high percentage of psoriasis patients, exhibit general psychiatric morbidity compared with patients who have other skin diseases
Psoriasis: This is a common, chronic and recurring skin disorder that changes and alters the life cycle of skin cells. It causes cells to accumulate quickly on the skin surface. The extra cells from the skin forms a thick, itchy, silvery scale and a red patch. It can appear at any part of the body such as the knee, scalp, elbow etc. it is treated with drugs applied to the skin, ingested and with ultraviolet radiation. This disease has affected about 1%-5% of the world population and it is more common to the light skinned people. Psoriasis may persist throughout a person’s life as it comes and goes but it is usually reduced during the summer period when the skin is exposed to ultraviolent radiation and flare ups are common during
This essay explores and reflects on the lived experiences of an elderly patient living with the long-term condition (LTC) of psoriasis. A case study is used to illustrate some of the key features of LTCs and the impact they can have on a patient’s physical, psychological and social state. It is also going to be looking at the effect some of the key features can have on a patients support network or family. In addition it will examine the nurses role in the management of LTCs and the health and social policies that may have an impact on the care received by patient with LTCs.
The pathophysiology of psoriasis is characterized by epidermal hyperproliferation, enhanced antigen presentation, T helper 1 cytokine production, T cell expansion, and angiogenesis. (El-Darouti and Abdel Hay, 2010 ).
Background: Plaque psoriasis is a painful autoimmune disease that affects up to 3% of the US population.1 Moderate-to-severe psoriasis can have significant psychological and physiological effects on a person’s health and although psoriasis can be controlled, it cannot be cured, so medications play an important role in reducing related comorbidities and improving patients’ quality of life.2
Psoriasis is as the author of the article “Update on Psoriasis and its Management” states, a genetically inherited chronic inflammatory
Psoriasis is a chronic skin disorder, easily identified by its symptoms of white, scaly skin and red lesions, though not so easily cured or understood. In psoriasis, skin cells mature faster than the body can shed them, causing a buildup. Although there are many theories as to what the cause of such a disease might be genetics, stress, or other triggers no one is quite sure why the disease occurs, or what could be a possible way to fully cure it. In this essay we will explore the symptoms, types, and effects of this condition, and also some of the known treatments.
The physician, Galen identified psoriasis as a skin disease through clinical observation. He was the first to call the disease psoriasis. The Greeks has a word for it -psora meaning “to itch”. In 1809, Dr. Robert Willan first recognized psoriasis as a specific clinical entity. Psoriasis is knows as a skin order that forms thick,red, bump patches that are covered with silvery scales. They can appear anywhere on the body,but mostly on the scalp,elbows,knees, and lower back of the body. No one really knows the cause of the disease. However, experts do believe that it has something to do with the immune system that causes inflammation that is triggering new skin cells.
When you have psoriasis, scaly and itchy lesions pop up anywhere on your body, but the scalp area is one of the more common places for them to develop. This makes treatments tricky since you don't want to use products that affect the appearance of your hair or that make your hair fall out. If your case is mild, you may be able to treat your outbreaks with over-the-counter products. If you have several lesions on your scalp, it's best to work with a doctor and use prescription-strength medications to get your psoriasis under control more quickly. Here are some treatments that may help with scalp psoriasis.
As previously stated, Psoriasis is caused by a mistaken trigger in the Immune system. “Normally, T cells help protect the body against infection and disease.” (NIAMS, 2013) When the disorder triggers the immune system, it causes the T cells to activate and trigger other immune responses. This will develop the redness and scaling of the
The Integumentary is a vast organ system composed of exocrine glands, hair, nails, and the most commonly known organ, the skin. As a large system, it can be susceptible to many different types of diseases, one of these diseases are called Psoriasis. This affects a large portion of the Integumentary system, the skin. Psoriasis are considered to be a widespread, common and recurring disease that can be chronic at times. Psoriasis are defined by its appearance of light silver in color, flaky, rash on many parts of the Epidermis.
Psoriasis is the chronic inflammatory condition that occurs as part as of a complex set of the interaction between genetics, immunological, systemic and environmental factors (Green, 2011; Penzer & Ersser, 2010). Psoriasis is not contagious like all chronic condition (Penzer & Ersser, 2010). In the Caucasian population, the population that get psoriasis is about 2%.
When I do not have psoriasis, it's hard to remember. As a child, my scalp has psoriasis - it's really sad that this disease can affect the kids.
Both men and ladies develop psoriasis at equivalent rates, those that developed signs of a skin condition don’t seem to find it to severe enough to visit a dermatologist at first, instead many apply moisturizers in hopes that if centralized its smooths out from the being visible and woman apply make-up for cover up while males usually do not seem to hide it or care. The analyzable data gathered for individuals with psoriasis is critical to comprehend because this skin disorder and its level of severity may lead to developing comorbidities linked with psoriasis. In the journal Medicine and Dermatology Follow (2009), FDA reported once individuals decide to visit a doctor’s office to inquire about the disturbing appearance of what may be psoriasis doctor’s account 88% of the time the diagnosis is in fact psoriasis and is already at its moderate stages. There are about 150,000 new cases each year in the United States for psoriasis (Medicine and Dermatology Follow, 2009). In the study of Pietrngelo & Krucik (2016),1.9 percent of African-Americans have psoriasis, contrasted with 4.6 its most astounding in percent of Caucasians. Psoriasis often grows between the ages of 15 and 40, but it can develop at any age. A few babies have psoriasis, even though this is viewed as uncommon. The first signs of psoriasis are in females mostly in the 20 years of age while in males the mean age is 29 years of age (Pietrngelo & Krucik,
There are many types of diseases of the Integumentary System, some worse than others, yet they still all affect the Integumentary System in some type of way. Psoriasis is a skin disease marked by red, itchy, scaly patches, and it is an immune-mediated, inflammatory condition which affects nearly 3 percent of the world’s population, is not contagious, and it affects both males and females, no matter what age or ethnicity they are. Psoriasis could be painful, their lesions could crack open and bleed, and itching could also occur, though sometimes it might not even be painful at all. In the research article “Patient Preferences for Treatment of Psoriasis with Biologicals: A Discrete Choice Experiment” by Christian Kromer, Marthe-Lida Schaarschmid,
Psoriasis was copied from the Greek word psora, which means “to itch” (Jean, 2011). Psoriasis is a chronic, long lasting autoimmune skin disease that disturbs the speed of the growth cycle in skin cells (Stress-Related Disorder Sourcebook, 2016). Normal, healthy skin cells replace dead skin cells every twenty-eight to thirty days (Langley, 2005). Skin is the largest organ in the body. It protects from the environment, regulates body temperature, helps coordinate immune system regulation, function of touch sensations, waterproof, and prevents toxin substances from entering the body (Langley,2010). Psoriasis effects greater than three percent