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Symptoms And Treatment Of Rubella

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Introduction
Rubella virus was the first teratogenic agent to be identified as it disturbs the embryonic development. While the clinical symptoms of rubella infections acquired postnatally are usually mild, and many infections are asymptomatic, this virus can be even fatal for the fetus during pregnancy. The rubella virus replicates in the upper respiratory tract and nasopharyngeal lymphoid tissue, and the virus then spreads to surrounding regional lymph and then bloodstream. It’s highly contagious disease as its transmission occurs by spread of the airborne droplet from person to person. Perhaps it’s the critical period of fetus development and the damages of this teratogenic virus that many studies have been done regarding to the different aspects of congenital rubella.

Congenital rubella syndrome

The mechanism by which the rubella virus infects the fetus and causes fetal damage is poorly understood. However different suggestions has been proposed to explain the pathogenesis of congenital rubella infection. One study suggests that the immune tolerance in pregnancy explain the RV pathogenesis, as immune system undergoes changes to adapt to fetus and placenta, it becomes more vulnerable. Also the limited maternal passive immunity in the fetus during early pregnancy means that the virus can spread through the bloodstream of the mother and may damage different organs like the placenta. As a result of placental damage, the virus is enabled to cross the placenta into

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