Synthesis Of Conventional L Aminoacids Capped Zns

The objective of this lab was to create a ketone through an oxidation reaction using a using a secondary alcohol and oxidizing agent in order to use that ketone in a reduction reaction with a specific reducing agent to determine the affect of that reducing agent on the diastereoselectivity of the product. In the first part of this experiment, 4-tert-butylcyclohexanol was reacted with NaOCl, an oxidizing agent, and acetic acid to form 4-tert-butylcyclohexanone. In the second part of this experiment, 4-tert-butylcyclohexanone was reacted with a reducing agent, either NaBH4 in EtOH or Al(OiPr)3 in iPrOH, to form the product 4-tert-butylcyclohexanol. 1H NMR spectroscopy was used to determine the cis:trans ratio of the OH relative to the tert-butyl group in the product formed from the reduction reaction with each reducing agent. Thin-layer chromatography was used in both the oxidation and reduction steps to ensure that each reaction ran to completion.

Experiment 55 consists of devising a separation and purification scheme for a three component mixture. The overall objective is to isolate in pure form two of the three compounds. This was done using extraction, solubility, crystallization and vacuum filtration. The experiment was carried out two times, both of which were successful.

Data Table 2 shows the results gathered after the purification of 3-nitrochalcone. Since only half of the crude product was used, the theoretical yield for the crystallized product was determined to be 2.1 g. This led to a percent yield of 39%. The melting point of the crystallized product was also determined to be 142℃, which differed slightly from the literature value of 146℃. As a result, the product, 3-nitrochalcone, was not completely pure. It probably contained water and alcohol, because any impurities would have lowered the melting point. Considering the fact that the crude product was not thoroughly dried before purification, water and ethanol were already in the product. Even after crystallization into “pure 3-nitrochalcone”, the product was also not completely dried. The yield should have been much lower than 39%. If the product is not allowed time to dry, not only water, but methanol, which was the solvent that was used to crystallize the crude, would be in the product. Both the crude and crystallized 3-nitrochalcone were analyzed by infrared spectroscopy to test and prove these

The cyclic ketone cyclohexanone was oxidized to adipic acid using the oxidizing agent nitric acid. The experiment yielded 0.2667 grams of adipic acid, giving a percent yield of 113.97%. Although the product was allowed to dry for one week, residual moisture was still present in the sample and a melting point could not be obtained. This error in the experiment either resulted from adding too much water or not allowing the product to remain in the Hirsch vacuum filtration for long enough to sufficiently dry.

8. ISBN: 0-558-05245-2 Virtual ChemLab: General Chemistry, Student Lab Manual/Workbook, V. 2.5, Third Edition, by Brian F. Woodfield and

7. Plan: Each student in a group of three will work to purify the product of the reaction with cis-stilbene, trans-stilbene, or styrene. The crude products will be purified through recrystallization. This purification process will be performed several times. When the recrystallization is complete, a vacuum filtration will be executed to filter out the crystals. An NMR spectrum will be taken of the recrystallized product.

To start off, in an Erlenmeyer flask approximately 0.51 g of E-stilbene with 10 mL of acetic acid was dissolved. A hot water bath was prepared and the mixture was warmed until the solid is completely dissolved. After the solution was dissolved, 1.02 gram of pyridinium hydromide perbromide was added. The crystals around the flask were rinsed with a small amount of acetic acid and the solution was continued in the hot water bath for one to two minutes.

The purpose of this experiment is to examine the reactivities of various alkyl halides under both SN2 and SN1 reaction conditions. The alkyl halides will be examined based on the substrate types and solvent the reaction takes place in.

Zinc, number 30 on the periodic table and a bluish-white metallic element, exists naturally in air, water and soil. It is present everywhere in the environment. All life on earth has evolved in the presence of zinc. Natural processes such as erosion, forest fires, aerosol formation above the seas and volcanic eruptions continuously transport Zinc. Zinc melts at about 420° C and boils at about 907° C. Zinc is efficient for plants. Zinc-deficient soils present in many parts of the world are a cause of low crop yields. Not only does it help plants but also the human body. It is responsible for the proper functioning of more than 300 enzymes in the human body, and is vital for the immune system. It will also fight against cold

The reaction took place in a conical vial and .2mL of each of the reactant samples were added to it along with some 95% ethanol. Two drops of NaOH were added shortly after and stirred at room temperature for fifteen minutes. The vial was cooled in and ice bath and crystallized. Vacuum filtration was performed to filter the crude product. The crude product was recrystallized using methanol and filtered again. We made one change to the procedure and instead of using .7mL of ethanol we

This stock solution was prepared freshly and kept in the dark at ambient temperature when not in used.  About 100 mg of Quercetin (Qu), Rutin (Ru), Silibinin (Si), Qu NPs, Ru NPs, Si NPs, Qu-Ru NPs and Qu-Si NPs (Test samples) were dissolved in 100 ml with methanol, to obtain a solution of 1000µg/ml. From this stocking solutions, various working conc. were produced to get concentration of 100, 200, 300, 400, 500 µg/ml with distilled water.

The quinoxalinones 3–26, listed in Table 1, were prepared following the procedure depicted in Scheme 1. According to our previous report [3], the diamine 1a–d was reacted with the suitable -ketoester 2a–c in 10% aqueous solution of sulfuric acid to give compounds 3–6, 8–11, 13–16, 18–20, 23, 25 and 26 in good yields, while the condensation of 1a with 2c, to obtain compounds 22 and 24, failed. The latter compounds were obtained by condensation in ethanol at room temperature for 1 h, while the isomeric pairs 7/12 and 17/21 were obtained by condensation in ethanol under reflux for 3 h of the diamine 1e with the -ketoesters 2a,b,

Part 2 to determine the empirical formula and percentage yield of the compound synthesized in Part 1. Spectrophotometry is a routine laboratory test that has the added advantage

3. Szafran, Z.; Pike, R. M.; Singh, M. M. Microscale Inorganic Chemistry - A Comprehensive Laboratory Experience. Wiley, 1991.

Subsequently, 10mL of 3.5% H2O2 were added dropwise to the reaction mixture and was stirred for 20 minutes before heating to boiling at 80°C for 5 minutes. The reaction mixture was then taken off heat and allowed to cool undisturbed in an ice-bath for 30 minutes. Suction filtration was performed after to collect the crystals from the chilled solution The product was then washed with chilled 95% ethanol (2 x 15mL) and followed by diethyl ether (2 x 10mL). The crude product was then left to dry before recording the yield. 20mg of the crude product is then accurately weighed out and dissolved in deionized water in a 25mL volumetric flask. Deionized water was added to the volumetric flask to the mark and the UV-vis absorption spectrum of the crude product was recorded.