Essay on Synthesis of Aspirin

5275 Words22 Pages
The Synthesis of Aspirin

Chemistry Standard Level Lab Report

Data Collection and Processing and Conclusion and Evaluation

Date: December 8th, 2011

Purpose:

The purpose of this lab was to synthesize aspirin, determine the theoretical yield, compare the percent yield to the theoretical yield and test the purity of aspirin by adding Iron (III) chloride to the product.

Hypothesis:

I hypothesize that salicylic acid will react with acetic anhydride to produce acetylsalicylic acid (aspirin) and acetic acid (vinegar).

Variables:

Independent and controlled variables: The amount of sulfuric acid used for catalysis and the amount of salicylic acid and acetic anhydride.
Dependent variables: Theoretical and actual yield of
…show more content…
The aspirin crystals were washed by pouring 10 mL of water over them through the funnel.

The filter paper, holding the aspirin crystals, was removed from the funnel and was left to dry before being weighed. Once the aspirin crystals were weighed, the theoretical yield and the percent yield of the experiment were calculated. The procedure was repeated once more using the same steps.

Procedure for the test of purity of aspirin:

0.1 gram of salicylic acid was weighed in a tray and was then added to a test tube containing 2.0 mL of Iron (III) chloride, which was measured using a 10 mL graduated cylinder, to test for phenols.

0.1 gram of commercial aspirin was weighed in a tray and was then added to a second test tube containing 2.0 mL of Iron (III) chloride, which was measured using a 10 mL graduated cylinder, to test for phenols. This was repeated once more to validate results.

0.1 gram of my product from the first trial was weighed in a tray and was then added to a third test tube containing 2.0 mL of Iron (III) chloride, which was measured using a 10 mL graduated cylinder, to test for phenols. This was repeated once more to validate results.

0.1 gram of my product from the second trial was weighed in a tray and was then added to a fourth test tube containing 2.0 mL of Iron (III) chloride, which was measured using a 10 mL graduated cylinder, to test for
Open Document