Synthesis of Cinnamaldehyde

The product obtained had a melting point of approximately 107 °C and a weight of .324 grams. Some of the product would not dissolve in water and so was removed through vacuum filtration, which left .141 g not dissolved in solution. It took 13.2 mL of sodium hydroxide to turn the solution of the product dissolved in water pink. A molecular weight of 138.63 g/mol was calculated from the data. These results indicate that the product was 2-methylbenzoic acid, the Grignard reagent was 2-methylphenylmagnesium bromide, and the unknown bromide solution was 2-methylbromobenzene. Calculations showed that the limiting reagent of the Grignard preparation was magnesium and that the experiment had a 23.13 % yield.

Discussion: As seen in the melting point determination, the average melting point range of the product was 172.2-185.3ºC. The melting points of the possible products are listed as 101ºC for o-methoxybenzoic acid, 110ºC for m- methoxybenzoic acid, and 185ºC for p- methoxybenzoic acid. As the melting point of the sample

In this study, the unknown compound (No. 55) was obtained, and its identity was determined using three methods: the solubility testing, the melting point analysis, and Thin Layer Chromatography (TLC) method.

In this era, looks are the priority. Gaining fats are nightmares for those who are health conscious. Everyone is striving to burn the unwanted pounds. A few kilograms on the weight scale can change the appearance of the person and it affects the life of some people a lot. Now, there are millions of diet plans and workouts available, but people opt for the one that is genuine and consumes relatively less time. One of the ways to reduce weight is by using cinnamon. Cinnamon plays a hugepart in reducing weight. It is useful for our body and aids a great deal tolose weight fast.

Hydrazones are compounds obtained by the condensation of hydrazides with aldehydes or ketones. Substituted hydrazones can be obtained by introducing substituted hydrazides and carbonyl compounds. If the substituent is an acyl group, then it is called acylhydrazone. The –C=O group provides the possibility for the electron delocalization within the hydrazone moiety. General formula for a substituted acylhydrazone is shown in Fig. 1.

The goal of this lab was to synthesize benzocaine by utilizing Fischer esterification, reflux, and melting point determination techniques. These techniques were successfully performed and the synthesis was successfully performed. Although, the synthesis was not very efficient due to the low percent yield of the product (28%) and the melting point of the product not correlating to that of benzocaine.

Cinnamon has many uses in diabetic and obesity patient as it has been used for decades. Generally, cinnamon is used for spice and aromatic. Each part of the tree which are bark, and twigs have its benefits. For inner bark, it is used mainly for digestive upsets such as indigestions, general sluggishness, colic and diarrhoea. In China, they believe that cinnamon is good for all sorts of “cold” conditions, from the common cold and stomach chills to arthritis and rhematism as it promotes sweating. Cinnamon bark can be prepared in three form of traditional medicine which are decoction, use for chronic diarrhoea or complaints related to weakened kidney, tincture and powder, use for “cold” conditions affecting the kidneys and

Hydrazones and their derivatives constitute a versatile class of compounds in organic chemistry. These compounds have interesting biological properties, such as anti-inflammatory, analgesic, anticonvulsant, antituberculous, antitumor, anti-HIV and antimicrobial activity. Hydrazones are important compounds for drug design, as possible ligands for metal complexes, organocatalysis and also for the syntheses of heterocyclic compounds. The ease of preparation, increased hydrolytic stability relative to imines, and tendency toward crystallinity are all desirable characteristics of hydrazones. Due to these positive traits, hydrazones have been under study for a long time, but much of their basic chemistry remains unexplored. N-Acylhydrazones (NAHs),

In recent decades there has been increased public interest in prevention, control and treatment of diseases by medicinal plants. However, providing the required resources from wild growing species couldn’t always meet the demand. Anthropogenic interferences with natural habitats and ecosystems, and threats posed by humans to comply the demand make many medicinal plants endangered. Cultivation of medicinal plants to provide needed plant materials is one of the strategies to conserve the plants and avoid depletion of wild resources. Furthermore, using cultivated plants material instead of wild collected ones has some other advantages such as precise control of growing condition, harvesting at right time, and reduction the possibility of adulteration. However, it should be considered chemical constituents may vary between cultivars and wild grown ones by type or amount and then their biologic effects may differ from each other. Several studies have compared cultivated and wild grown species especially from the point of view of essential oil composition and then similarities and differences between samples have been reported (1-6). As an example Chatzopoulou et al., have shown although

Synthesis, Thermolysis, Photolysis and Animicrobial Evaluation of some Novel Semicarbazones and Thiosemicarbazones Derived from 3-Methyl-2-benzothiazolinone Hydrazone.

From the ancient times spices and herbs has been mainly used as natural food preservatives, as food additives and as flavouring agents. Various spices indicates antimicrobial action against distinctive sorts of microorganisms. This project proposal gives a literature review considering antimicrobial action of vital oils generally utilized as spices and herbs. For e.g.: garlic, mustard, bay, cumin, thyme, basil, oregano, pepper, ginger, sage, rosemary etc. Against most regular bacteria and fungi that contaminated food (Staphylococcus spp, Salmonella spp, Escherichia spp and many others). Antimicrobial activity is depending on the content of extracts and essential oils, types of food and microorganisms, type of spice and herb and chemical composition.

GC-MS has been exhibited to be an important investigative device for the examination of primarily nonpolar parts and unstable natural items,i.e, mono-and sesquiterpenes. Chen et al. depicted a technique using direct vaporization GC-MS to decide approx 130 unstable constituents in a few Chinese therapeutic herbs. They detailed a productive GC-MS technique with EI for the partition and structure detection of the constituents in ether-removed unstable oils of Chinese rough medications, Jilin Ginseng, Radix aucklandiae, and Citrus tangerina peels. The parts, transcendently monoterpenes, of the unstable oil of the oleoresin of Pestacia atlantica var. mutica have been broke down as of late by GC-MS together with the use of on-line

SYNTHESIS, SPECTRAL AND BIOLOGICAL ACTIVITIES OF PYRIDINE 2,6 DICARBOXALIC ACID HYDRAZONE DERIVATIVES AND ITS METAL COMPLEXES

Inhalation of vapours of the essential oils kill invaders attached to the inner respiratory lining and work synergistically with the body defences. In this study, Five essential oils were used against aspergillus fumingatus using cut plug method and the essential oil showes inhibitory activity against A. flumingatus the most effective oils against A.fumigatus were found to be of Cinnamomum verum (Cinnamon), Lavandula angustifoli (Lavendre), Foeniculum vulgare (Fennel), Zingiber officinale (Ginger) and Cinnamomum camphora(Camphor) with inhibition zones ranging between 11 to 31 mm Treating the organism with cinammom essential oil led to an external changes, irregular cell shape and disintegration of fungus cell wall under transmission electron microscope Analysis by GCMS showed at leas 8 components, esters were the most abundant group of compounds.

Preliminary qualitative phytochemical screening of Cajanus cajan root extract in 70% ethanol showed presence of flavonoids, tannins,