Systemic Lupus Erythematosis Research Paper

Lupus is a lifelong, autoimmune disease. This means that the immune system of a person with lupus cannot tell the difference between its own cells and what is foreign. This leads to the immune system attacking healthy tissue throughout the entire body.

Lupus is a chronic autoimmune disease that can happen when your body's immune system attacks Some tissues and healthy organs. It is natural that the immune system protects the body from viruses and bacteria, but in the lupus attacks the healthy tissue. this disease can called systemic lupus erythematosus or SLE. It is difficult to diagnose the disease because its signs and symptoms tend to mimic other diseases. What makes diagnosis difficult is that it can not determined from just one test but by several tests it can be determine. These tests include blood, urine and physical examination. Lupus most common in women and often of childbearing age. however, children, men and teenagers can develop this disease too. most people develop this disease between the ages of 15-44 (Anonymous, 2013). Also, Scientists believe that there are 5 million people around the world who have a form of lupus and that it spreads in African-Americans, Hispanics and Asians (Anonymous, 2016) . Lupus is like any disease it has causes, symptoms and Methods of Treatment for this disease.

Systemic Lupus Erythematosis is an autoimmune disease where the body’s immune system mistakenly attacks healthy tissue. To be diagnosed with this disease there are many test and labwork your physician will perform on you. These test used to diagnose SLE may include antibody test, including antinuclear antibody panel, complete blood count, chest X-ray, kidney biopsy, urinalysis, antithyroglobulin antibody, antithyroid microsomal antibody, complement components C3 and C4, coombs’ test-direct, cryoglobuline, ESR, kidney function blood tests, liver function blood tests, rheumatoid factor, and antiphospholipid antibodies.

Lupus erythematosus is an autoimmune disease that affects the connective tissue of the body. The course of disease is variable and unpredictable, with episodes of remission and relapse. Only a small percentage of patients (10%) have long-lasting remissions. Lupus takes two forms. Systemic lupus erythematosus (SLE) is a multisystem inflammatory disease that affects any body system but primarily the musculoskeletal, cutaneous, renal, nervous, and cardiovascular systems. Discoid lupus erythematosus (DLE) is a less serious form of the disease that primarily affects the skin. DLE is characterized by skin lesions of the face, scalp, and ears. Long-standing lesions can cause scarring, hypopigmentation, and redness. Only 5% to 10% of patients with

Treatment is vital toward helping lupus patients expand their life span, but there are many issues regarding medical treatment. Trethewey (2004) discussed that due to the level of difficulty with developing effective lupus specific treatments because of the mechanisms that normally prevent the immune system from attacking an individual’s own body are defective; there are general treatment options. The general treatment options are dependent on the individual’s signs and symptoms and severity. According to Lupus Foundation Of America (2013), the general treatment options that are available for individuals with lupus are Anti-Inflammatories (reduces inflammation and pain), Corticosteroids (act as naturally occurring hormones), Antimalarials (mainly used for skin rashes, mouth

Lupus is a chronic, autoimmune disease that can damage any part of the body like your skin, joints, and, or organs inside the body. When someone has lupus something goes wrong with their immune system. Because it is an autoimmune disease the immune system cannot tell the difference between the foreign invaders, like the flu, and the body’s healthy tissues. So it creates autoantibodies that attack and destroy the healthy tissue, which causes inflammation, pain and damage in various parts of the body. It is also a disease of flares meaning when the symptoms worsen the person will feel sick, and remission when the symptoms improve the person will feel better. It is also a disease that can range from mild to life threatening.

Lupus erythematosus is a chronic autoimmune disease. An autoimmune disease occurs when the body's tissues are attacked by its own immune system. Patients with lupus have unusual antibodies in their blood that are targeted against their own body tissues.

Systemic lupus erythematosus(SLE) is an autonomous disorder with a number of autoantibodies(double stranded DNA,ANA). It causes inflammation diffusely through the body(skin, brain, kidneys,joints) and the blood. SLE has numerous abnormal blood tests associated with it(anemia, anti-Sm, anti-phospholipid antibodies), but this is not the same thin as knowing what causes SLE. its cause is a mystery.The etiology of SLE is unknown but multiple genetic, epigenetic, and environmental risk factors have been implicated. The inheritance of genes alone is not sufficient for developing SLE, suggesting the influence of environmental triggers on disease expression. Despite the significant role of the environment in modulating autoimmunity pathogenesis,

Lupus, also referred to as systemic lupus erythematosus (SLE), is a chronic autoimmune disease that is caused when the body’s immune system attacks its own tissues and organs. Common symptoms include rashes, fevers, skin lesions, organ damage, and stiffness and swelling in muscles and joints. These symptoms cause patients physical pain, which has been shown to increase psychological distress. In other words, lupus patients that experience pain also experience high levels of depression, anxiety, and stress. It was hypothesized that lupus patients may feel a sense of helplessness over their disease in response to the fluctuating degrees of pain. Researchers tested this hypothesis by using Martin Seligman’s learned helplessness model, which states learned helplessness is a feeling of powerlessness as a result of persistent past failure. In this study, the patient’s level of continuous pain would

Systemic Lupus Erythematosus (SLE) has its own specific sign and symptoms, which each person with this disease may has slightly different symptoms which can range from mild to severe and may come and go over time. The common symptoms of SLE are painful or swollen joints and muscle pain, unexplained fever, red rashes (butterfly rashes) which usually on the face, chest pain upon deep breathing, unusual loss of hair, pale or purple fingers or toes from cold or stress which also know Raynaud’s phenomenon, sensitivity to the sun causing the skin to become seriously irritated, swelling (edema) in legs or around eyes, mouth ulcers, swollen glands and extreme fatigue. However, SLE’s symptoms mostly include painful joint, unexplained fever and extreme

Systemic lupus erythematosus (SLE) is a chronic inflammatory and autoimmune disease of multifactorial etiology that can affect many organs and systems (Sato, 2002).

Systemic Lupus Erythematosus, usually called as SLE or Lupus, is a type of incurable autoimmune disease which affects the hematologic, dermatologic, renal organ system and musculoskeletal. In other words, it attacks mostly the connective tissues of the body. Generally, an autoimmune disease happens when the immune system attacks healthy tissues of the body by producing protein called autoantibodies. This will cause inflammation and damage to the tissues. Inflammation causes indication of injuries such as redness, swelling and pain. The etiology of SLE is still unknown to the world. There is, however, increasing evidence that the presence and accumulation of apoptotic cells play a role in autoimmunity (White, S., and Rosen, A., 2003).

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Systemic Lupus Erythematosus (SLE) is an acquired, multiorgan, autoimmune disease. Clinical presentation is extremely variable and heterogeneous. It has been shown that SLE itself is an independent risk factor for developing both arterial and venous thrombotic events since SLE patients have an Odds Ratio (OR) for thrombosis that varies depending on the clinical and laboratory characteristics of each study cohort. The risk of developing a thrombotic event is higher in this setting than in the general population and may further increase when associated with other risk factors, or in the presence of inherited or acquired pro-thrombotic abnormalities, or trigger events. In particular, a striking increase in the number of thrombotic events was observed

SLE is an autoimmune disease that is more common in women versus men. Ninety-six percent of SLE cases are in women, whereas only four percent of SLE cases occur in men. The survival rate of systemic lupus erythematosus has improved due to many factors such as earlier diagnosis, better management of disease and prevention of organ damage. Despite these advances in care, the life expectancy of patients with SLE remains, lower than the general population. SLE may also be associated with an increased prevalence of cervical cancer and other cancers thereby shortening their life spans.