Systemic Lupus Erythematosus (SLE)

Systemic lupus erythematosus (SLE) also referred to lupus dates back to the middle ages and has made an explosion in the past 60 years. Even though more than 1.5 million Americans have lupus and 90% of lupus sufferers are women, between the ages of 15 to 44 (Lupus Research Institute), there is little awareness about the disease. 72% of Americans aged 18-34 have either not heard of the disease or know nothing about it (Medical News Today). However, researchers continue on working to have a better understanding of SLE factors, pathophysiology, current treatment and new prospects for treatment.

It is not rare for individuals with lupus to undergo muscle throbs and discomfort or have inflammation of certain muscle groups, which causes faintness and loss of intensity. More than 90 percent of people with lupus will encounter joint and/or muscle pain at some time during the path of their illness. In lupus, the immune system of the body raids its own cells and tissues. Precisely, the joints, skin, kidneys, lungs, heart, nervous system, and other organs of the body are affected. Lupus affects generally 10 times as many women as men. Most often, lupus develops in people 18 to 45 years old. (Lahita) Though lupus is most dominant among women, it also may affect men and children, as well as individuals of all ages. Lupus effects each person

Do you know that there is currently three types of lupus? Discoid lupus, systemic lupus erythematosus, and lupus like a disorder called destroyer made lupus. Discoid lupus remains limited to our skin and be present in the form of a rash that appears on your face, neck or scalp. The appearance of the rash may possibly be more outward on areas of the skin exposed to electromagnetic lighting. While close by stand many forms of lupus epidemics the most communal is elevated, incrusted and rosy nevertheless not irritated. SLE remains commonly extra plain than discoid lupus. Do you know Discoid lupus is a form of lupus that is be able to cause inflammation in your organs?On behalf of nearly half of our society, this can be to

Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disorder that can cause significant morbidity and mortality. A large body of evidence has shown that African Americans experience the disease more severely than other racial-ethnic groups. We performed a systematic review in the PubMed and Medline Databases of articles published between January(?) 2000 – December 2014 to evaluate research focused on SLE in African Americans. Articles were classified according to their level of evidence. Our literature review reported a wide range of adverse outcomes in

The American College of Rheumatology (ACR) and the Georgia Council on Lupus Education and Awareness (GCLEA) partnered to increase community awareness on Systemic Lupus Erythematosus (SLE) and to further educate lupus patients throughout the underserved region of southwest Georgia. Systemic Lupus Erythematosus, the most common form of lupus, is an autoimmune disease that causes the immune system to attack needed body tissues (“Lupus,” 2018). This specific type of lupus affects major functions of the body including the brain, lungs, skin, and kidneys. Lupus is commonly difficult to diagnose in humans due to its vague symptoms that mimic the symptoms of other major conditions (‘Lupus,” 2017). Presently, researchers are unaware of the origins

Do not seek for the answers that cannot be given, for you would not be able to live them, and the point is, to live everything. Live the questions now, and perhaps, without knowing it, you will live along some distant day into the answers (Paul J. Donoghue 47).” Talk about quote. “Lupus can cause serious kidney damage; kidney failure is one of the leading causes of death among people with lupus. If your brain is affected by lupus, you may experience headaches, dizziness, behavior changes, hallucinations, and even strokes or seizures. Many people with lupus experience memory problems and may have difficulty expressing their thoughts (Lupus).” Having lupus also increases your risk of “Infection, cancer, bone tissue death, and pregnancy complications like miscarriages. But thank god when I got pregnant with my third child, Brandon, he come out perfectly. I was so lucky and happy,” said Kizzy

If you must have a terrible disease, Lupus is a particularly shitty one to have; not only does it make you feel horrible every single day, but to make matters even worse, most people don 't understand what it is or even really believe that it 's a thing. If you have cancer, people pray for you, run 5ks in your name, and make T-shirts with motivational sayings like "Save the Tatas" on them. When you have Lupus, people tell you that you should really work on a more positive mental attitude and make a five-year plan that includes a job that you 'll probably be able to do despite your inconvenient infirmity.

Lupus affects men and women most commonly between the ages of 15-44. This disease can have many signs and symptoms, the most common being soreness of joints, and a red rash on the face or body. More severe cases can result in trouble breathing and arrhythmias.

Lupus is a chronic, lasts for a long time, inflammatory and autoimmune disease. Lupus is characterized by being autoimmune which is caused by antibodies made by the immune system that attacks the body and its tissues. Also, Lupus is a systemic disease. Systemic diseases in medicine mean:"affecting the whole body, or at least multiple organ systems."(1) Moreover, this diseases has a unique characteristic of flare-ups or relapses, when the disease shows severe symptoms, and remissions when the disease gets better and shows mild or no symptoms at all.(2)

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Systemic lupus erythematosus (SLE) is a chronic inflammatory disease, immune-complex-mediated multi-systemic autoimmune condition of multifactorial etiology (Mak and Tay 2014).

Kristan is a 49-year-old female who suffers from systemic lupus erythematosus (SLE) (M32.19), along with osteoarthritis, vitamin D deficiency, CVA, and anemia. Her symptoms include fatigue, joint pain, swelling, morning stiffness, rash, sleep disturbances and fever. Kristan has tried and failed various treatments including quinacrine, prednisone, and plaquenil, all provided her with little to no relief. Systemic Lupus Erythematosus (SLE) is the most common form of lupus, a chronic, incurable autoimmune disease producing autoantibodies that can attack almost any system in the body. Lupus can impact the lives of patients in many different ways with varied and often unpredictable symptoms. Benlysta is currently the only medicine specifically

Systemic Lupus Erythematosus is a chronic autoimmune disease which causes inflammation of your joints, tissues, and organs. The inflammation presents itself as heat, pain, swelling and redness. SLE is a variable disease that doesn’t take any one particular course; therefore its unpredictability makes it even more devastating. No two people will experience the same disease symptoms or severity level. As S.L.E progresses there will be periods of very subtle to no symptoms at all called remission or an exacerbation of symptoms called flares.

This study was conducted on thirty adult patients with SLE Patients were selected from rheumatology outpatient's clinic of AL-Zahraa hospital, Cairo, Egypt, during the period from June 2015 till October 2016. SLE patients fulfilling the American College of Rheumatology (ACR) revised criteria for the diagnosis of SLE were included11. Patients with clinical manifestations of SLE such as malar rash, photosensitivity, alopecia, oral ulcers arthritis, nephritis, neuropathy and hypertension were included in the study. Current medications were recorded , Patients with diabetes mellitus, malignancies and those with a diagnosis of mixed connective tissue disease were excluded. The study also included thirty age and sex matched apparently healthy

SLE is a chronic autoimmune inflammatory disease that targets the kidneys with pathologically evidence in about 90% and clinically in about 50% of patients. Lupus nephritis is a foremost risk factor for overall morbidity and mortality in SLE, and even with potent anti-inflammatory and immunosuppressive therapies still ends in CKD or ESRD for many patients (Salem Almaani et al., 2016). So, an early diagnosis of LN has an imperative clinical implication in administrative treatments of SLE patients (Jing et al., 2017).