Systemic Lupus Erythematosus ( Sle )

1689 WordsNov 26, 20167 Pages
Millions of people around the world suffer from incurable, autoimmune diseases. Even with the tremendous advancement in medical field, there are many questions unanswered. More and more diseases of unknown cause are being evolved every now and then, which are threatening to the mankind. Systemic lupus erythematosus (SLE) is a classic example of such a disease. SLE is a chronic, often life-long, autoimmune condition, ranging from mild to severe in severity. SLE may affect many organs in the body, including but not limited to kidneys, skin, joints, respiratory and nervous systems. The name of this disease describes it; word systemic indicates the widespread involvement of various tissues and organs of the body. Lupus is a word derived from Latin language, which means wolf, referring to the rash on the face which was thought to resemble a wolf bite. Erythematosus is a Greek word, meaning red, referring to the color of the rash. In SLE, the immune system of the body is unable to differentiate between its own cells and tissues and foreign substances (antigens). In response, antibodies are produced which attacks body’s own cells, resulting in inflammation and pain. The medical community is still trying to determine the exact cause of SLE, which is unknown so far. It is proposed that there is likely an interaction between susceptible genes and environmental factors. Wallace (1995) believes that of those who carry lupus genes, only 10% will ever develop the disease. SLE is a
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