Systemic Lupus Erythematous

This research paper will explain what lupus is to help others get a better understanding of this diseases. It will cover the history ,and tell us how many people are affected by this silent killer. There are several different types of lupus in this paper we will discuss Systemic Lupus Erythematosus which effect different organs.One will learn which part of the body this disease affects,the signs and symptoms, even the treatment and the side effects.

What is Lupus? Lupus is an autoimmune disease in which our autoantibodies target self-proteins, known as ANAs. Systemic Lupus Erythematosus (SLE) is understood to be caused by our genetics and the environmental triggers from our everyday lives. There are four different types to this incurable but manageable disease, Cutaneous Lupus Erythematosus, Drug-induced Lupus Erythematosus, Neonatal Lupus, and Systemic Lupus Erythematosus. I will cover all of them, the main focus is on Systemic Lupus Erythematosus which is commonly diagnosed in females.

“Systemic Lupus Erythematosus is a chronic, inflammatory autoimmune disease in which the immune system attacks the body’s own structures” (Beattie, 2013). This means that the disease that has a slower onset, but it also has a long-term effect and the signs and symptoms will be continuous. Systemic Lupus Erythematosus (SLE) can affect the entire body or any organ in the body, including: the kidneys, swelling of the joints, affecting the blood vessels and the skin.

The exact cause of Lupus is unknown. Lupus mostly affects women who are of childbearing age. Lupus has a tendency to run in families where genenectic factors may play a role. Evidence has shown that Lupus may be more common in people of African or West India descent. Researchers believe Systemic Lupus Erythematosus may be triggered by a virus or some type of in infections in people who are genetically susceptible to this disease.

Lupus is a chronic, autoimmune disease that can damage any part of the body like your skin, joints, and, or organs. When someone has lupus, something goes wrong with their immune system. Because it is an autoimmune disease, the immune system cannot tell the difference between the foreign invaders, like the flu, and the body’s healthy tissues. So it creates autoantibodies that attack and destroy the healthy tissue, which causes inflammation, pain and damage in various parts of the body. It is also a disease of flares meaning when the symptoms worsen, the person will feel sick, and remission, when the symptoms improve, the person will feel better. It is a disease that can range from mild to life threatening.

A person’s immune system fights off harmful bacteria that get into your body. An autoimmune disease confuses your immune system, causing it to fight against your body. There are many different autoimmune diseases that a person’s body can develop. One of the diseases that stood out to me is systemic lupus erythematosus, also known as SLE. According to What is Systemic Lupus Erythematosus, systemic lupus erythematosus is a chronic, multisystem autoimmune disorder that can affect nearly every major organ system, causing inflammation, tissue injury, organ damage, and ultimately, organ dysfunction. No one knows what causes a person to have SLE. Many doctors believe that a person is born with certain genes in their body causing them to have SLE.

Lupus is a disease that can destroy any and every part of your body, for instance, your skin, joint, and even your organs. Lupus is a very tricky disease and no one knows what the cause of it is, the body natural defenses system is the immune system and with lupus, the immune system attacks healthy tissues instead of attacking only the damaged tissues. For example when you get things like a bacteria and viruses the body will kill both good and bad cells because it can’t tell the sick cells apart from the healthy cells. People who suffer from this disease experience a lot of pain. The disease is lifelong and has no cure however most people with lupus can control the symptoms and prevent severe damage to their organs. African American women are

Currently there are no treatments for cure of SLE. The only treatments available are treatments to suppress the progression on the disease, treatments to address complications cause by SLE, and treatments to relieve patients from the discomfort. There is no known etiology for SLE; therefore, there are no prevention methods for SLE. The recent improvement of the understanding of autoimmune diseases; in general, has helped improve prognosis. Faster and more precise diagnosis, leading to earlier treatment in suppressing the progression of the disease is allowing more patients to live a normal life span. Also, the 2011 FDA approval of the biologic drug called Belimumab has contributed to the improvement of prognosis. More research directed towards the understanding autoimmune disorder is needed. Unfortunately, the current knowledge is not enough to provide adequate and timely diagnosis. Due to the tight commonality among autoimmune diseases, a thorough understanding of the immune system is required to develop more effective treatments and a cure for systemic lupus

The diagnosis of SLE is difficult. Autoimmune diseases are a group of related conditions that present similar symptoms. One autoimmune disease is not a unique disease with its own unique symptoms. Instead autoimmune diseases are a group of related conditions (see fig 2 and table 2). Currently there are no definite number of how many autoimmune diseases exist; however, there is a range of autoimmune diseases that varies from 80 to as

Signs can also come on suddenly or develop slowly. “SLE most commonly produces inflammation of the skin, joints, nervous system, kidneys, lungs, and other organs. A Charachteristic butterfly rash, or erythema, may be present on the face, spreading from cheek to cheek, across the nose, to the other cheek. SLE may begin acutely with fever, fatigue, joint pain, and malaise, or may develop slowly over a period of years, with intermittent fever, malaise, joint deformities, and weight loss.” (Drzymkowski, 2013, p. 149). Most people with lupus have mild disease characterized by episodes — called flares — when signs and symptoms get worse for a while, then improve or even disappear completely for a time. If you experience these types of symptoms, it is important to visit a doctor to seek treatment. To screen the patient for Lupus, this requires a complete medical evaluation and once diagnosed, seek a referral to a

The diagnosis of SLE is difficult. Autoimmune diseases are a group of related conditions that present similar symptoms. One autoimmune disease is not a unique disease with its own unique symptoms, instead autoimmune diseases are a group of related conditions (see fig 2 and table2). Currently there are no definite number of how many autoimmune diseases exist, however, there is a range of autoimmune diseases that varies from 80 to as many as 120 (EHP,

Lupus erythematosus is a chronic autoimmune disease. An autoimmune disease occurs when the body's tissues are attacked by its own immune system. Patients with lupus have unusual antibodies in their blood that are targeted against their own body tissues.

Systemic lupus erythematosus(SLE) is an autonomous disorder with a number of autoantibodies(double stranded DNA,ANA). It causes inflammation diffusely through the body(skin, brain, kidneys,joints) and the blood. SLE has numerous abnormal blood tests associated with it(anemia, anti-Sm, anti-phospholipid antibodies), but this is not the same thin as knowing what causes SLE. its cause is a mystery.The etiology of SLE is unknown but multiple genetic, epigenetic, and environmental risk factors have been implicated. The inheritance of genes alone is not sufficient for developing SLE, suggesting the influence of environmental triggers on disease expression. Despite the significant role of the environment in modulating autoimmunity pathogenesis,

One cause of this disease is environment. Some examples would be UV rays from the sun and fluorescent light bulbs, Sulfa drugs, Infection, Emotional stress, and more. Researchers do not know yet what type of environment specifically, but there ideas are most likely true. Another cause is hormones. Studies have shown that women began to have more lupus

There are many different types of diseases one’s body can suffer from, but one unique type of disease is an autoimmune disease. What makes autoimmune diseases different than other diseases is with an autoimmune disease the body ends up attacking itself. “The immune system inappropriately identifies its own proteins as foreign and mounts a response to destroy these self-proteins” (Linton, 2016). One in particular autoimmune disease is Systemic Lupus Erythematosus, also known as SLE. SLE has a debilitating impact on the body, is defined by a very distinctive mark on the face, difficult to diagnose, and currently has no cure.