Signs and symptoms of Takayasu arteritis
This is a rare systemic swelling of the large vessels and mostly affects women of child bearing age. Takayasu arteritis is defined as the granulomatous inflamation of the aorta and its major branches. We need to understand the nature of this disease and the medications to be taken in order to prevent complications. This disease is spreading worldwide at the rate of 2.6^million cases per year. It is observed mostly in Japan, China, Korea, Indian, Thailand, Singapore, Turkey, Israel and central south America as well. Most patients are aged from 4-63 years. Complications of the disease may lead to stroke, intracranial hemorrhage, seizures, ischemia, organ failure, occlusion, fetal injury, hypertension, retinopathy, reno-vascular hypertension and valvular heart disease. This is a chronic relapsing and remitting disorder, the overall survival rate is 90% for 10 years. 5 and 10 year survival rates are 69% and 36%. There is a strict management of cardiovascular risk factors. This disease makes one substantially morbid and may be life threatening. It may also lead to panarteritis with intimal proliferation. It usually lasts for many years. When it attacks women it attacks any or all major organs. This disease is in all parts of the world, although it is most prevalent in Asians.
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Signs and symptoms of Takayasu arteritis
Stage1
Fatigue : abnormal tiredness and loss of energy
Fast weight loss : abnormal loss of body mass leading to undernourishment
Muscle aches : severe pains on the muscles due to lack of nourishment
Joint pain : severe joint pains at the ends of the
Stenosing tenosynovitis, or most commonly referred to as trigger finger, is a condition where one of the fingers is stuck in a bent position. The affected finger may straighten in a snap similar to a trigger being pulled and then released. This situation usually occurs when there is inflammation in the area causing space within the sheath surrounding the tendon to become narrow. To help alleviate it, there are home remedies for trigger finger pain.
Aim: The purpose of this report is to learn about quadriceps tendonitis. By examining a range of internet articles based on the condition I hope to reveal information on the injury. How it occurs, its symptoms, how it can be diagnosed, the treatment process and furthermore the future issues that one could possibly experience.
DOI: 8/26/2007. Patient is a 46 year-old male general production worker who sustained a work-related injury to his left ankle as a result of walking over an uneven driveway. The patient was subsequently diagnosed with tendonitis and degenerative joint disease. As per SOAP notes dated 7/6/16, the patient complains of ankle pain and that he is out of medications. Objective findings reve3aled pain with motion and while in cast. It was further noted that it seems to cycle and stable. Motion in the “STJ” residual from failure of fusion pain producing relative to time on it, in cast/out. Plan notes that left ankle lateral aspect is the area of tenderness. Current medications are Norco and
Polyarteritis Nodosa is an autoimmune disease caused by immune deposition in the wall of small to medium sized muscular arteries.13 This process promotes infiltration with polymorphic leukocytes and liberation of necrotizing enzymes, leading to thrombosis, tissue ischemia, fibrosis, and ultimately tissue scarring. PAN may affect virtually every organ system and has a wide constellation of clinical manifestations (Table 1).14 Establishing the diagnosis of PAN is very difficult as there are no laboratory abnormalities specific for PAN. Acute phase reactants, such as erythrocyte sedimentation rate and C-reactive protein, are commonly increased.14 Chronic anemia is also frequently present.14 Histopathological evidence of vascular inflammation
Exercise is suppose to help you, but when can it be harmful? Tendonitis is a debilitating tendon injury that is usually named by the location of the body where the injury occurs. There are countless cases of people who develop tendonitis not only because they had an inactive way of life, but because of the overuse of certain parts of the body. The most common types of tendonitis are the patellar (knee), ankle and foot tendonitis, and tennis elbow. There are different ways that a person can develop tendonitis and different symptoms, but they are treatable.
Tendons attach muscles to bones. They also help with joint movements. When tendons become irritated or swollen, it is called tendinitis.
Laminitis is also known as lactic acid acidosis and founder, it is an inflammation of the sensitive lamina of the hoof. Laminitis is caused by a variety of factors and is more so common in dairy cattle. Lamina is a sensitive tissue located between the claw bone and the hoof wall, which keeps the hoof wall attached to that bone. When that lamina that is within this capsule is disrupted or has a lack of blood flow it will become weak causing the coffin bone to slide around, rotate, and or sink inside the hoof. Laminitis can occur for many different reasons whether it is trauma, a metabolic disease, infection, or a dietary disturbance. Laminitis can be seen in three forms, acute, sub-acute, and chronic. Acute laminitis is short term, it can be
Degenerative calcific aortic stenosis is found in elderly patients with prolonged stenotic condition while rheumatic stenotic conditions a resultant from the rheumatic fever damage to valve leaflets is caused by increased turbulence across the valve and is more prominent in the young and adult patients. The congenital condition of aortic stenosis with bicuspid valve is more prominent in young and middle aged patients, though the cause of this is quite uncertain it is often considered as a genetic abnormality or hemodynamic molding theory also suggests that decreased blood flow during the developing stages could possibly result in failure of separation of the leaflets [24]. Uni cusped aortic stenosis is more often found in infants and children [25]. The obstruction caused by the wall increases the ventricular pressure inside the left ventricle causing it to put more effort while trying to eject the blood into the aorta. Due to this prolonged development the ventricle develops resistance against this increased ventricular pressure due to the obstruction by thickening the ventricular walls. The consequence of this remodeling is the gradual effect on ejection
elbow, knee, wrist and heel, although it can happen anywhere in the body where tendons are
We consider that the valve regurgitation in the Behcet’s patients may be the result of functional derangement and structural damage caused by the underlying non-specific vasculitis of Behcet's disease. Nojiri et al[16] reported that the histology of the resected aortic wall showed destruction of the lamina elastica, perivascular fibresis, and cell infiltrations in the tunica media. Aortic cusps showed nonspecific change with fibrosis and inflammatory cell infiltrations. The aneurysmal wall showed massive fibrinoid degeneration and granuloma formation. In Inchul Lee’s clinicopathologic study of 12 cases, the data suggested that acute endothelialitis is the basic pathologic change in all cardiovascular Behcet’s disease[14]. Their findings support our hypothesis.
Diseases of the aorta. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 78.
Tendinitis is the inflammation or irritation of tendons. A tendon is a thick fibrous cord that attaches muscle to bones. It causes tenderness and pain around a joint. It can occur anywhere in the body's tendons, although it mainly occurs around the shoulders, elbows, wrists, knees and heels. Tendinitis has many common names, such as; Tennis elbow, Golfer's elbow, Pitchers shoulder, Swimmer's shoulder, and Jumpers knee. If it is severe and you rupture your tendon, then surgery is a big part of getting the tendon repaired. For most people it is not severe, therefore it can be treated with rest, physical therapy, and medications. Most cases get help with self-care, although you should see a doctor when your signs and symptoms interfere with your daily activities for more than a few days.
Edema is an abnormal buildup of fluids. It is more common in your legs and thighs. Swelling of the feet and ankles is common and becomes more likely as you get older. It is also common in looser tissues, like around the eyes. There are many possible causes of edema. Eating too much salt and being on your feet or sitting for a long time can cause edema in your legs and ankles. Hot weather may make edema worse.
A large vessel essentially refers to the aorta and its largest branches that are directed to the head and neck and the extremities. The hallmark in terms of pathology with large vessel vasculitides is that chronic inflammatory lesions are primarily found inside of the walls of vessels and not on the outside. This is a key distinction that can be used in order to separate large vessel from small vessel pathologies, which present with inflammation on the outside of the vessel wall in addition to being found within. The two main large artery vasculitides that will be discussed below are giant cell arteritis (GCA) and Takayasu disease.
The list of potential pro inflammatory cytokines important in the pathogenesis of RA and other autoimmune and inflammatory diseases has been extended by another cytokine -interleukin IL-23. This cytokine plays a potential role in immune modulation of different subpopulations of T helper (Th) cells in concert with IL-12 (Lupardus and Garcia, 2008).