Our aim was to describe the demographic, clinical, and laboratory characteristics of Takayasu’s arteritis the in northeast of Iran. Introduction: Takayasu’s arteritis (TA) is a chronic vasculitis of unknown etiology. TA affects adolescent girls and young women. It has a worldwide distribution, with the greatest prevalence in Asians 1-2. A generalized inflammatory syndrome with fever, night sweats, malaise, anorexia, weight loss, and diffuse myalgia often dominates initial manifestations of TA. These symptoms are frequently misdiagnosed as infection 3.Takayasu’s arteritis primarily affects the aorta and its primary branches 4. The inflammatory processes cause thickening of the walls of the affected arteries. The proximal aorta can become dilated due to inflammatory injury. Narrowing, occlusion, or dilation of the arteries in varying degrees results in a wide variety of symptoms 5.
Involvement of the carotid and vertebral arteries leads to neurologic and ophthalmologic symptoms, including dizziness, tinnitus, headaches, syncope, stroke, and visual disturbances. Atrophy of facial muscles and jaw claudication are mostly late manifestations. Occlusions of the brachiocephalic and subclavian arteries impair blood flow to the upper extremities, presenting as arm claudication, pulselessness, and discrepant blood pressures. The detection of bruits can be helpful in making the diagnosis 6.
TA is not very rare in Iran 7. We aimed to study the clinical, laboratory characteristics,