Taking a Look at Metronidazole

2825 Words Feb 22nd, 2018 11 Pages
Mascaratti OA.Bacteria verses Antibacterial Agents:An Integrated Approach.Washington,DC;ASM Press;2003.
[Antibiotics Basis for Clinicians:The ABCs of Choosing the Right Antibacterial Agent By Alan.R.Hauser page 92 read on 23rd Feb,2014]
Metronidazole is a drug widely used for the treatment of infections caused by anaerobic organism either(a)protozoa such as Trichomonas vaginalis, which provokes vaginal discharges,and Entameoba Histolytica,causing ameobic dysentry or (b)bacteria,e.g in abscesses and tissue necroses caused by Bacteroids fragilis and antibiotic induced pseudomembranous colitis(Clostridium difficile).The ultimate target may be DNA in bacteria and possibly,Carbohydrate metabolism in protozoa.
Metronidazole is a small molecule that can passively diffuse into bacteria.An important component of its structure is nitro group that extends from the core five membered ring,this…

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