Taking a Look at Rheumatoid Arthritis

1445 WordsFeb 2, 20186 Pages
“Rheumatoid arthritis, RA, causes premature mortality, disability and compromised quality of life in the developed and emerging world (cdc.gov).” RA is the most common of chronic inflammatory arthritis. Rheumatoid arthritis is an autoimmune condition; it is a chronic inflammatory polyarthritis, in which more than five joints are affected. Rheumatoid arthritis is a systemic inflammatory disease which it manifests itself in numerous joints of the body. The inflammatory process mainly affects the lining of the joints, usually small joints then leading to many other organs. “Rheumatoid arthritis is a type of chronic arthritis that occurs in joints on both sides of the body. This symmetry helps distinguish rheumatoid arthritis from other types of arthritis. Rheumatoid arthritis may also affect the skin, eyes, lungs, heart, blood, or nerves (webmd.com).” There are subsequent exacerbations in which rheumatoid arthritis develops. First being an abnormal immune response, this caused inflammation of the synovial membrane. The inflamed synovial membrane leads to erosions of the cartilage and bone and in some cases joint deformity. Due to inflammation of the synovial membrane vasodilation, formation of exudate, and increased permeability; this causes swollen, pained, and red joints. Synovitis cells will proliferate and inflammation recurs. Synovitis occurs due to immune abnormality. Rheumatoid factor, RF, is an antibody against immunoglobulin G; it is present in the blood, also in the
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