Targeted Therapy

Chemotherapy drugs used to treat cancer kill the most rapidly dividing cells in the body,

There are many different type of cancers, there are also many different types of treatments. One of the most known types of treatments would be chemotherapy. Chemotherapy can be used for a wide range of different types of cancers and diseases, and each of the different types of cancers or diseases require a different group, and sometimes order, of chemicals to properly treat the cancer or disease. These chemicals include: Alkylating agents, Antimetabolites, Anthracyclines, Topoisomerase inhibitors, mitotic inhibitors, corticosteroids, and more. Each of these drugs previously listed have its own cancer type(s) or disease(s) that it can assist in treating. Some of these cancers include: Leukemia, Lymphoma, Hodgkin disease, multiple

Some of traditional drugs may be effective in patients whose cancers have a specific molecular target, and not for other patients. To solve this problem of patient-specificity, pharmaceutical research have seen the expansion of individually tailored cancer treatment, which is an application of targeted therapy, and this is where biopharmaceuticals are. As an increasing part of the population is diagnosed with cancer and as these patients live longer, increasing care will be given to patients who have received these drugs. Moreover, in the case of cancer therapy, those drugs and especially with mABs are a promise of less side effects : recombinant DNA technology makes it possible to genetically engineer an antibody to reduce the risk of host immune response.

Many doctors, physicians, researchers and biotech companies--including the revolutionary Seattle Genetics research facility--are now turning to antibody-assisted cancer treatments and precisely targeted cures instead of treating cancer with a cocktail of chemicals and radiation that generate risky side effects and damage the healthy tissue that patients need to recover. Cancers are among the most frightening and difficult-to-treat illnesses. Ranked as the leading cause of death and disability, cancer is actually an umbrella term that covers many different diseases. Each person faces a unique disease because cancers interact with the body's existing cells, so each case has a

Note: Always make objectives measurable, e.g., 3 out of 5 times, 100%, learn 3 skills, etc., unless they are measurable on their own as in “List and discuss [issue] weekly…”

When cells in the body start dividing and regenerating uncontrollably, they lead to cancer – and this is true for all the cells in the body. If the cancer is not nipped in its bud early on, it can spread to other parts of the body. This presents the common question asked regards cancer; how can it be stopped early on? The same can be said for cancers that start from the bone marrow such as multiple myelomas.

* Hormonal Therapy: Some cancers need hormones to grow, used to block cancer cells from getting hormones to grow.

I can draw from these results that as the chemotherapeutic drug concentration is increased the cell viability decreases. In HEPG2 the viability at the control was 100% but when the drug was added at concentration of 40µm the cell viability decreased to 2.62%. From these examples we can deduce that the chemotherapeutic drug added is successful in its use and that it is targeting the cancerous cells. The drug damages the genes present inside the cell line

Ms. X is a licensed clinical social worker specializing in cognitive behavioral therapy, dialectical behavior therapy and prolonged exposure, all being evidence based practices. She uses evidence based treatment modalities in her work. She keeps up on research studies for these treatments and new findings of strategies that she may be able to employ in her work. In addition, she collects data to inform her own work to better understand growth and if not, how she may be able to amend the treatment to recognize practice. She also reads research studies outside of her practice to learn new techniques which continually builds her knowledge base. Furthermore, she uses research to better understand trends on both a micro and macro level. This

As the cancer continues to spread throughout society, many treatments are creating in order to help the patients during their time in need. Although the most popular and used often

To first identify novel drug targets, I would thoroughly search the literature, look at online cancer resources and discuss potential targets with scientific experts at the Beatson and externally. Below I have outlined the key information that should be gathered.

• Targeted therapy. This treatment targets specific parts of cancer cells and the area around them to block the growth and spread of the

    Cancer is a disease in which cells multiply out of control and gradually build a mass of tissue called a tumor. There has been a large amount of research dedicated to the treatment and cure of cancer. Several types of treatments have been developed. The following are just some of the major examples of cancer therapy: surgery, chemotherapy, radiation therapy, biologic therapy, biorhythms, unconventional treatments, and hyperthermia. Each type of treatment is discussed in detail below.

The most significant challenge that I have faced is without a doubt my targeting and treatment as a result of racial and religious background. This is an ongoing issue that I still face to this day, however I have had multiple instances where students have harassed me brutally. I am a Muslim, and one instance that I remember vividly is during lunch, a white student walked by as I opened my backpack to grab my lunch and told me, "don't take that bomb out." That seared me badly, I laughed it off like a joke, but I still remember that kid and what he said about me. I also remember a teacher who bluntly told me that she didn't like me because of how I looked, I got put in the back of the class. During my time at CMH, a elder doctor and I got into

Every year millions of people are being freshly diagnosed with cancer and a healthy amount is diagnosed with some form of myeloid leukaemia. Few decades ago treatment options for myeloid leukaemia were not so diverse and mortality rate amongst patients were very high. Things have changed dramatically due to the introduction of various treatment options; patients are being able to lead a healthy life prior to their medication period. Though conventional chemotherapy is still used but there are a variety of drugs that have been introduced which could replace chemotherapy and stem cell transplantation in near future as these new generation of drugs have a very specific mode of action and they have a minimal side effect. For example Tyrosine Kinase