Teratogen

The science behind FAS is quite simple; as it is known that alcohol has a damaging effect on the body, it has similar consequences on the fetus. Since the fetus is constantly developing, the alcohol causes more serious defects to the unborn child. Alcohol exposure to a fetus is known as a teratogen. “Teratogens are substances or conditions that disrupt typical development in offspring as a result of gestational exposure and cause birth defects.” (Wilson & Fraser, 1977). Although the exposure to alcohol causes problems in the fetus, studies have shown that it may not accurately be the alcohol in the mother’s system that causes these defects, rather the byproducts that form when the body metabolizes the alcohol. This can lead to a decrease in brain cells, abnormal location of neurons, and gross malformation to the brain. Since alcohol causes this central nervous system damage, it is classified as a neurobehavioral teratogen, which is a group of teratogens that cause brain damage and modify behaviors. (Riley & Vorhees, 1986). The CNS damage is the primary defect due to alcohol and it is quite common to have these damages without any physical abnormalities. The more alcohol that is consumed the more birth defects that will arise in the

Fetal alcohol spectrum disorder (FASD) is a concise, uniform definition for conditions caused by prenatal alcohol exposure. FASD is a broad term used to describe the range of effects that can occur in an individual whose mother drank alcohol during pregnancy (Caley, Kramer, & Robinson, 2005). Fetal alcohol spectrum disorder can also cause growth retardation, birth defectscomma and deficits in cognitive, languagecomma and motor development (Coles et al., 2015). Fetal alcohol spectrum disorder is a teratogenic effect, which is caused by daily, chronic, heavy and frequent alcohol use while in utero. Chances of an infant diagnosed with FASD are 0.5 to 3 in 1,000 live births (Cone-Wesson, 2005). Fetal alcohol spectrum disorder has many different diagnoses. There is fetal alcohol syndrome (FAS), partial fetal alcohol syndrome (PFAS)comma and alcohol-related neuro-developmental disorder (ARND)comma all under the fetal alcohol spectrum disorder umbrella (Brown et al., 2015). Maternal alcohol use is correlated to the timing, frequencycomma and quantity of the consumption of alcohol during pregnancy. Drinking during the first trimester may not be as detrimental as drinking during the second or third trimester. The frequency of alcohol consumed is also a key factor in FASD, such as how often per day drinks are consumed, the quantity of alcohol consumed, and how many glasses or cans per day the mother consumes

The term “Fetal Alcohol Spectrum disorders” (FASDS) is used to describe the numerous problems associated with exposure to alcohol before birth. Each year in the United States, up to 40,000 babies are born with “Fetal Alcohol Spectrum disorders” (FASDs) (Substance Abuse and Mental Health Services Administration). Additionally, Fetal Alcohol Spectrum disorders (FASDs) comes with effects that range from mild to severe. These effects include mental retardation; learning, emotional and behavioral problems; and defects involving the heart, face and other organs. According to the U.S. Surgeon General, the patterns of drinking that place a baby at greatest risk for FASDS are binge drinking and drinking seven or more drinks per week (Surgeon General). However, FASDS can occur in babies of women who drink less. There is no way of measuring how much alcohol one can consume before defects occur, and no proof that small amounts of alcohol are safe. As little as one drink a day can cause a baby some degree of harm and interfere with their normal development.

“Fetal Alcohol Spectrum Disorder (FASD) is an umbrella term describing the range of effects that can occur in an individual whose mother drank alcohol during pregnancy. These effects may include physical, mental, behavioral, and/or learning disabilities with possible lifelong implications” (HHS, 2005). FASD refers to conditions such as: fetal alcohol syndrome including partial FAS, fetal alcohol effects (FAE), alcohol related neurodevelopment disorder, alcohol-related birth defects. The conditions that are involved with FASD can range from mild to severe and it is not likely that two people share the exact same symptoms.

As stated earlier, alcohol has its greatest effect on the developing embryo during the first trimester of pregnancy with its teratogenic effect causing mental retardation as well as characteristic craniofacial abnormalities that are characteristic of the disease. It has also been demonstrated with experimental animal models that there is a clear "dose-response" effect between the amount of alcohol consumed by the mother and the risk that is associated with developing FAS symptoms (Walpole, p. 875). It has been proposed by Walpole and associates that there are various degrees to which the fetus An be effected. Walpole uses the term "fetal alcohol syndrome" to refer to serious effects due to heavy maternal drinking and "fetal alcohol effect" to refer to those effects thought to occur with lower maternal alcohol intake (Walpole, p. 875). Regardless of the degree to which

Fetal alcohol spectrum disorder (FASD) is a general term consist disabilities when a mother consumes alcohol during her pregnancy. The medical prognosis of FASD includes: Fetal Alcohol Syndrome (FAS), Partial Fetal Alcohol Syndrome (PFAS), Alcohol Related Neurodevelopmental Disorder (ARND) and Alcohol Related Birth Defects (ARBD). Moreover, teratogen is a harmful agent that can interrupt the development of an embryo. For instance, alcohol is teratogen. As per Health Canada, FASD is a leading cause of a completely avertable developmental disability but it still affects approximately one percent of the Canadian population (Batshaw, Roizen & Lotrecchiano, 2012). However, there are many alterations to the disabilities and the development of sub-groups. Thereby, the term FASD is introduced to ensure the incidence of all the characteristics (mental, behavioral and physical) associated with prenatal exposure to alcohol. The exposure to alcohol during the pregnancy places the infant at the risk of developing problems such as abnormal appearance, low body weight, poor coordination, low intelligence, facial abnormalities, neuropsychological deficits, central nervous system deficits and growth delays (Riley, Infante & Warren, 2011). As the paper progress, we will discuss the characteristics, causes and the epidemiology of FASD. In addition we will all focus on the mental disorder such as Attention Deficit Hyperactivity Disorder (ADHD) associated with FASD and a

Fetal Alcohol Syndrome (FAS) refers to a group of physical and mental birth defects resulting from a women’s drinking alcohol heavily or at crucial stages during pregnancy. Fetal Alcohol Syndrome was first named and treated in the late 1960's. This condition results from the toxic effect of alcohol and its chemical factors on the developing fetus. FAS is the leading cause of mental retardation occurring in 1 out of every 750 births. The frequency of FAS occurs about 1.9 times out of every 1000 births according to the latest figures, and minor effects can be seen in up to 20% of pregnancies per year. This number changes drastically for women who are clearly alcoholics. As high as 29 children out of every 1000 births will suffer from FAS

Alcohol is known as one the most dangerous teratogens. Every time a pregnant woman drinks, she allows alcohol to enter her blood stream and make its way into the placenta. Unlike the mother, the fetus is unable to break down alcohol that makes the blood alcohol level of the fetus the same or higher than the mother (Burk, 2013). Fetal alcohol syndrome (FAS), and prenatal alcohol exposure (PAE) are considered some of the most serious consequences of maternal drinking during pregnancy. Children can exhibit physical abnormalities such as a flat mid-face, a thin upper lip, a smooth groove between the nose and upper lip, along with growth retardation, and cognitive difficulties. The affected children also have cognitive difficulties which include intelligence, language, memory, and learning (Wacha & Obrzut, 2007).

A teratogen is any agent or factor that can disrupt the development of an embryo or fetus, which may cause a birth defect or malformation. Whether it is a medication, disease or drug, when the mother is exposed the chances of problems arising with the baby increase. Only ten to fourteen days after conception teratogens can affect the fetus. At that stage in the pregnancy the egg has already been fertilized and attached to the uterus. This is known as the embryonic stage where if health isn’t a priority complications can occur. At this point the mother and embryo share a common blood supply therefore anything the mother does affects the embryo. This is also the stage in which most miscarriages occur. There are numerous teratogens but two

In the late 1950s, the Thalidomide drug was used in Europe to treat morning sickness in pregnant women among other things. This study involved manufacturing company providing samples of this drug to physicians and compensating them to study the benefits and results of this drug. Although allegedly this drug did not cause any harm to the mother the fetus suffered severe damage as a result. There were thousands of children born with

As previously mentioned, environmental factors, such as exposure to taratogens, can affect the development of the unborn child. Broderick and Blewitt (2105) define a teratogen as “substances or agents that can cross the placental barrier and produce fetal deformities when taken or absorbed by the mother during pregnancy” (p.619). These substances include drugs, alcohol, cigarettes, pollution, stress hormones, poor nutrition, and diseases, such as AIDS. Consumption of drugs and/or alcohol can lead to low birth weight, as well as, physical, cognitive, and behavioral abnormalities. Furthermore, more recent studies are showing that exposure to pollutants can affect an individual’s development. For example, a study of the

Alcohol is a type of teratogen, which is an agent that can caused birth defects to occur. The timing and the amount of exposure to a teratogen is crucial when it comes to a pregnancy. A mother’s use of alcohol can greatly affect an unborn child. The timing at which the effect of teratogens varies from person to person, but the time when the teratogens have the largest effect typically occurs during the periods of rapid prenatal development. Mothers who are pregnant, or who wish to become pregnant, should avoid consuming alcohol because the teratogens can affect the mother’s eggs. It is true that there are certain stages in the pregnancy where a certain amount of exposure to teratogens will only have little impact, but there is still some form of result. When

Thalidomide is a drug that was invented in Germany in the 1950’s. It was originally intended to treat respiratory infections but during testing, it was noted that the drug worked to relieve morning sickness for pregnant women. This new reason allowed the drug to be prescribed to many new patients all over the world. Eventually Thalidomide was discovered to be causing birth defects in all of the pregnant women that were taking it. It caused the fetus to not develop correctly by causing limbs of the body or ears to develop improperly or not develop at all. It also cause spinal cord and digestive system defects as well as problems to the heart and kidneys. Thalidomide stopped being prescribed but not before many children and families were affected worldwide who had taken the drug. It took a couple of years before other countries caught up to realize that thalidomide was causing the birth defects and removed from being an over the counter drug in many countries. It wasn’t until 1961 that it was completely removed after it was confirmed that it was causing birth defects. More than 10000 babies were born with defects and approximately killed 2000 before birth, but fewer than 100 were born here in the U.S.

According to dictionary.com a teratogen is “a drug or other substance capable of interfering with the development of a fetus, causing birth defects”. Teratogens are also substances that are found in the environment which are known to cause defects in fetal development. Teratogens are one of the leading causes of death to newborns in the nation. “There are four major factors that depend on the extent of fetal defects and those are the dosage, genetic makeup of the mother and the developing fetus, fetal age, an other negative influences on pregnancy” (Berk, 2012). Some of the common teratogens include alcohol consumption, exposure to radiation, environmental pollution, tobacco and or drug use, and certain prescription and non-

Why it is important in our society to know what teratogen is, and some ways to prevent this birth defect in our society. Teratogen is a agent that disturbs the development of an embryo. Well, what exactly causes these disturbances in the embryo? By taking medicine during pregnancy, medicine prescribe to new mothers can cause abnormality in pregnancy. Although many women take medications during pregnancy, the medicine prescribe can be harmful. A example may be a woman during pregnancy comes across morning sickness; therefore, she may ask her doctor to prescribe medicine to treat her morning sickness. A common medicine to take during the 60's was thalidomide. However, over the years researchers found that thalidomide caused partial absence