Teratogens and Their Effects on Fetus Development

The use of heroin, cocaine, and other illicit drugs has become a public health concern especially during pregnancy. Maternal substance abuse has become an issue during the crack epidemic in the 1980’s; however, there is an alarm rate of infants born addicted to heroin. More than 3.7% women have indicated the uses some form of illicit drugs during their pregnancy, as well as 1.9 % reports binge drinking (Bhuvaneswar el at., 2008; Grant el at., 2009). With this in mind, more than 375,000 infants are born to maternal substance abusers each year costing over $100,000 in medical expenses covered by the state (Reitman, 2002).

Substance abuse during pregnancy can have a negative force on the health and wellness of not only the fetus, but that of the mother. The harmful effects of medications, alcohol and illegal drugs on an unborn child can be devastating and can have significant consequences to its use. Sometimes the effects can be faced and treated, and other times the outcome is a lifelong challenge. During the prenatal period, it is important that new mothers are informed of the different types of abuse, how they may affect the fetus, and the adverse conditions their child may be faced with before and after birth.

Through the years, substance misuse in the United States has turned into an industrious issue influencing numerous people. In 2008, it was assessed that 17.8 million Americans beyond 18 years old where substance subordinate. Women who use medications during pregnancy can have an enduring impact on fetal. Medications can have an impact of maternal and child wellbeing, yet there are a lot of different variables, which influence it, poor social environment, nourishment, cleanliness, and sexual abuse. Regenerative interruption connected with heroin utilization has been shown in both and women and even low dosages of opiates can impede ordinary ovarian capacity and ovulation. The harm that goes hand in hand with substance utilization comes either straightforwardly from the impact of the medication itself or from issues identified with development and/or unexpected labor. The entanglements of jumbling components clamorous way of life, poor nourishment, liquor utilization and cigarette smoking influence the appraisal of the impacts of cocaine in pregnancy. In obstetric practice, 100% of pregnant women utilizing cocaine or heroin are cigarette smokers. Cigarette smoking is presumably the most well known manifestation of substance utilizes and is noteworthy corresponding considering ladies who use unlawful medications. Babies whose moms smoked in pregnancy have a tendency to have lower conception weights and diminished length, cranial and thoracic

The use of controlled substances throughout pregnancy is a very prevalent issue among society today. Controlled substances have devastating effects on not only the mothers using the substances, but also infants while they are in utero and after they are born. Many infants born to mothers, who are abusing drugs, suffer from life threatening illnesses and are forever affected through adulthood. Specifically, heroin is a common drug form that is often used during pregnancy and results in the life threatening effects mentioned above.

The National Health Institute (NIH) explains that addictive drugs such as amphetamines, cocaine, barbiturates, diazepam, and opiates consumed during pregnancy pass from mother to the fetus by crossing the placenta. This causes the baby to become addicted to these drugs along with the mother. Once born, the newborn no longer receives these drugs which then results in NAS (“Neonatal abstinence syndrome”, 2012a).

Some environmental factors of schizophrenia can be the over use of marijuana during the teenage years. As you can see in figure two a person who has developed schizophrenia has lost grey matter in their brain which can be see through a brain scan. After long use of marijuana, it causes similar outcomes to the brain and the loss of grey matter.

The rest of the United States have no specific laws. These laws were made by taking in account the risk of fetuses dying minutes after birth, being born with neonatal abstinence syndrome (NAS), heart defects, weak immune system etc. Additionally, there can also be long-term effects as stated in “March of Dimes”such as learning and behavior problems, sudden infant death syndrome (SIDS), and slower-than-normal growth problems (Street). The first weeks of a drug dependent baby are like an old wooden roller coaster full of trembles and thrills but in this case the thrills are not the pleasant ones. In article published by “Daily Mail,” it shows a disturbing video of a baby’s feet shaking vigorously. This is the kind of heart moving evidence that needs to be shown to society to grasp the depth of this

Even though there are many studies that highlight the damaging effects of maternal alcohol use on a fetus in utero, there are a multitude of other substances that are used by pregnant mothers that have similar and even, in some cases, more extreme repercussions such as marijuana, heroin, and cocaine. When speaking about pregnancy and drug use, the most common drug that comes to mind is alcohol. During 12 years of schooling, most people are exposed, at one point or another, to the idea of Fetal Alcohol Syndrome and the detrimental effects of alcohol on a fetus in utero. The effects of maternal use of the aforementioned illicit drugs is less studied, partially because they are used less frequently. It is important, however, that as a population, we become more educated about these drugs and the potentially life threatening outcomes for babies in utero.

feeding, sleeping, and crying). Aforementioned, to the birth, withdrawal symptoms may reacts due to cocaine and that keep the mother or child in the hospital for further examination. As a matter of fact, the unborn baby will suffer everything because of what their irresponsible mother does while she was pregnant. As newborn they are the one who suffers from mental retardation, irritable, cranky those even just a soft touch they will cry, have heart problems, birth defect, visual and hearing ¬¬¬¬-problems, or even worse death. In addition, sudden infant death syndromes (SIDS) maybe happen even after giving birth as well. (March of Dimes, 2013, para.9-12)

Children born to drug dependent mothers are susceptible to preterm delivery, decreased intrauterine growth, impaired neurological developments, as well as congenital abnormalities. Unfortunately, once the umbilical cord is cut, the withdrawal for the infants is initiated. The symptoms of withdrawal will be evident in 55% to 94% of infants within 2 to 7 days after delivery (Eichel & Johannemann, 2014).

(2010) explains that although methadone is used for opioid exposure especially during pregnancy, but also is linked to NAS when a fetus is exposed to methadone. With their focus of the effects of NAS on the central nervous system hyperirritability and autonomic nervous system dysfunction Jones et al. also focused on the different effects of methadone versus those of buprenorphine, which has less substantial research. The points of study included number of newborns requiring treatment for NAS, peak score on a NAS scale, amount of morphine given through out treatment, length of hospital stay and the head circumference. Overall they only found significant differences in outcomes for the total morphine required as well as the length of the neonates hospital stay. When exposed to buprenorphine prenatally the newborns required 89% less morphine during treatment and 43% less time in the hospital than those exposed to methadone (Jones et al.,

In the past 20 years, prescription opioid abuse has been a rapidly growing issue in the United States. This rapid increase in abuse has led to more overdose deaths, and the increase of individuals pursuing treatment for their addiction (Brady, McCauley, & Back, 2013). The rising frequency of maternal opioid abuse affects thousands of mothers and newborns each year. According to the National Institute on Drug abuse, the use of opiates during pregnancy can result in a drug withdrawal syndrome in newborns called neonatal abstinence syndrome (NAS). Almost every drug passes from the mother's bloodstream through the placenta to the fetus. Illicit substances that cause drug dependence and addiction in the mother also cause the fetus

The first two weeks of pregnancy are a critical time during this period major organs start the development process. The use of illegal drugs such as, methamphetamine, cocaine or heroin during pregnancy can potentially lead to a profound effect on both mother and baby. The drugs can be transmitted from the mother to baby through the placenta. As a result, mother could suffer a miscarriage, premature labor and hemorrhaging, additionally her ability to make rational decisions can be impaired. Potential effects for the baby; low birth weight, organs not properly functioning,

Many women, including teens, abuse drugs while they are pregnant. This rate is especially high to those who are homeless, underprivileged, or live in a broken home. In order for drug abusers to even have a chance at beating their addiction they have to have support whether it’s family, friends, or boyfriend/spouse. They must also let the abuser now all the consequences to themselves and the unborn child. There are many consequences when using drugs during pregnancy such as miscarriage, health risks to baby, and health risks to the mother. And learning disabilities and brain damage to the fetus.

According to dictionary.com a teratogen is “a drug or other substance capable of interfering with the development of a fetus, causing birth defects”. Teratogens are also substances that are found in the environment which are known to cause defects in fetal development. Teratogens are one of the leading causes of death to newborns in the nation. “There are four major factors that depend on the extent of fetal defects and those are the dosage, genetic makeup of the mother and the developing fetus, fetal age, an other negative influences on pregnancy” (Berk, 2012). Some of the common teratogens include alcohol consumption, exposure to radiation, environmental pollution, tobacco and or drug use, and certain prescription and non-