formed red platelets. In Sickle cell disease, or SCD, the hemoglobin in red platelets gathers together. This in turn causes red platelets to get firm and C-formed. The most well-known signs and indications of SCD are anemia and pain through the body. Sickle Cell Disease occurs most commonly in individuals whose families descend from West Africa, South or Central America (particularly Panama), Caribbean islands, Mediterranean nations, (for example, Turkey, Greece, and Italy), India, and Saudi Arabia
Thalassemia is basically a name for similar groups of inherited blood diseases that involve missing or abnormal genes regarding the protein in hemoglobin which is the red blood cells that carry oxygen throughout the body. I will discuss the different types of Thalassemia, how Thalassemia is diagnosed, and the treatments available. I will also discuss the complications and side effects of the treatments, the disease’s causes and effects, and how it is more dominant in some parts of the world than
This paper is written about the disease Alpha Thalassemia and it affects from the cellular to how the organism is impacted. It will cover the basis of the disease including inheritance and symptoms. Then, how and where the mutation occurs that causes the disease. The paper will then discuss the protein that is involved in the disease and how the mutation affects the production of the protein. The production can either be still functioning, completely shut down, slowed, or part of the protein could
occurrence of the disease is very rampant as it is a multiethnic part of Sudan (Sabahaelzain & Hamamy, 2014). Finally another study on the presence of alpha thalassemia as well as HbS examined it importance in blacks. The experiment that was done nearly thirty years ago found that the expression of the alpha thalassemia gene was beneficial for the patients’ survival with sickle cell disease. The reasoning behind alpha thalassemia’s favorable character is because of its ability to
Sickle Cell Disease Sickle Cell Disease or also widely known as Sickle Cell Anemia is a genetic mutation caused in red blood cells destroys its own cells within and reshaping the cell wall resembling crescent or sickle shape; getting its name of the sickle cell disease. These sickled shaped cells attempt to perform its normal function of circulating oxygenated and deoxygenated RBC and gets lodged in small vessels causing vaso-occlusion. Where vaso-occlusive take effect, rest of the body is not receiving
the average age of death was about 43 years for females and 41 years for males. About 1 in 6 deaths occurred in those under 25 years of age and nearly half of all deaths occurred in those over 44 years of age. “The sickle cell gene is found most commonly among individuals of African ancestry, but it also has a significant incidence in Mediterranean, Middle Eastern, and Asian Indian populations.” Among one in 12 African Americans carry the sickle cell gene. For Hispanic-Americans, one out of every
2002). Hemoglobin S causes sickle cell anemia which leads to sickle shaped erythrocytes which can block the blood vessels thus causing pain and damaging essential organs or the sickle shaped cells can disintegrate thus causing anemia (Ashley – Koch, 2000). Hemoglobin C causes the parasitized erythrocytes to accumulate in the brain thus causing cerebral malaria (Miller, 2002). This mutation also causes hemoglobin C disease, with symptoms like hemolytic anemia, enlarged spleen and sometimes jaundice
used heroine. The nurse should recognize that the woman is at increased risk for: A. Erythroblastocis fetalis (2ndary to physiological blood disorders i.e. Rh incompat) B. Diabeted Mellitus (unrelated to drug use/abuse) C. Abruptio placentae (more commonly seen with cocaine/crack use) D. Pregnancy-induced hypertension. 5. A client with insulin-dependent type II diabetes and and HbA1c of 5.0% is planning to become pregnant soon. What anticipatory guidance should the nurse provide this client? A. Insulin
concept commonly known as designer babies. Also, in 1978, the first germ-line genetically modified mouse was created, which lead to the development of somatic cell nuclear transfer in 1991. This technique was used to create a cloned embryo by the use of a donated nucleus. In 2001, genetic therapy had been around for about a year and these advancements began to be used for sex-selection of children (Lee, 2013). The current genetic altering technique that is being studied and practiced is called “clustered
various drugs; commonly infectious diseases during pregnancy of the mother such as viruses or toxoplasma, and rubella are another cause of genetic disorders [4]. Genetic disorders may also be a result of chronic diseases such as hypertension, diabetes, and various environmental factors. On the other hand genetic disorders can be inherited from parents, which include sickle cell anemia and other major diseases [5]. Therefore, such conditions could be detected through a procedure called "Genetic Screening"