Thalidomide Research Paper

A little white pill, sold as an over-the-counter drug, lined the shelves of pharmacies across the globe. Originating from the German drug company, Chemie Grütinethal, this pill was advertised to a highly receptive international market and was a success in 1959. Several years later, physicians began to form a link between phocomelia, a birth deformity, and pregnant woman who ingested the German-created drug. That little white pill is known as Thalidomide. Staying in the market for almost six years, Thalidomide changed the lives of mothers and their newborns for the worse making it one of the largest pharmaceutical failures in the course of mankind. Although the horrific effects of distributing Thalidomide in the late 1950s is historically

He illustrates all the wrong doings of the pharmaceutical companies from their unethical ‘standard company sales pitch’ to their ‘deadly drug.’ He also shed light on all those who were on the brink of discovery on the drugs deadly secrete. Dr Leslie Florence published a paper linking thalidomide to nerve damage in 1960 followed by an interview some 51 years later. After inserts of evidence in the past tense he refers back to the trial in the present tense continuing the narrative. The structure of his writing follows a narrative rather than a diary or catalogue.

Thalidomide is potent hypnotic antiemetic, a drug that is effective in treating nausea and vomiting, and was used as a sedative (Inakanti 190). At the time sleeplessness was prevalent, and Thalidomide was

As I have mentioned, inhaled nitric oxide, epoprostenol, iloprost, and sildenafil are the common treatment for pulmonary hypertension that I would encounter in the hospital where I am currently employed. Nitric oxide and iloprost are administered through inhalation, epoprostenol by continuous intravenous infusion, and sildenafil is taken orally. The main advantage of inhaled route for the treatment of PH is the direct delivery of drug to the target organ thus, reducing the systemic side effects (Hill, Preston, & Roberts, 2015). It also improves the gas exchange by dilating the vessels supplying the ventilated areas (Hill et al., 2015).

Methaqualone, is also referred to as Disco Biscuits, Down And Dirties, Jekyll-and-Hyde, Joe Fridays, Lemmon 714, Lemons, Lennon's, Lovers, Ludes, Mandies, Mandrake, Q, Qua, Quack, Quad, Quaaludes, Soaper, Supper, Vitamin Q, The Love Drug, Wallbangers, Whore Pills, and Sopor. This list of street names for the drug goes on and on.

In 1996, Another novel use of sertraline was discovered by Pfizer and was granted a patent. the new patent claimed that sertraline can be used for treating cancer. (WO 96/22085)

At present, ceftriaxone (intramuscular) is the only reliable first line antimicrobial left for use as monotherapy in most global settings to treat gonorrhoea.10,17 Although recommended antimicrobial treatment for uncomplicated gonorrhoea cases is ceftriaxone 500mg and azithromycin 2g.2,32 Yet, within the last decade gonorrhoea strains resistant to ESCs have been isolated.10,17 This is alarming as there is no reliable alternative antimicrobial to treat gonorrhoea.10,17

SR described the feeling as sensation of warmth and safety whenever he chased heroin. It made him feel relaxed and confident. At a higher dose, he felt as if in a dream-like state. He knew that heroin was a drug that could bring harm to his health, but he could not forget the euphoric feeling after the first chase. SR frequently went to the secluded places with his friends which were known as “ports”. Initially SR spent RM 5 for each heroin use. After a month, he realized that the amount of heroin was insufficient to produce the euphoric effect that he wanted. He then spent approximately RM 20 to RM 30 for each heroin use. He chased heroin

Different researchers concluded that the Neurontin drug has an inadequate evidence of the effectiveness in treating the drug as mentioned above even the researchers tried in a double-blind study

One of the reasons why the children in the cancer ward have a bald head is chemotherapy. Chemotherapy drugs are very strong and powerful medications that attack growing cancer cells as well as other growing cells in your body. That includes hair roots. Baldness is not permanent. After treatment your hair will take 4 or more months to grow back. It may come back a different color and texture but that is not permanent.

Chemotherapy is the gold standard that frequently used to lessen symptoms in patients with advanced breast cancer and reduce the risk of return in patients with localized breast cancer. In principle, chemotherapy involves the administration of chemical agents that target proliferating cancer cells. The aim of chemotherapy is to shift the balance of cell proliferation to one of cell death or apoptosis (Moulder et al., 2008; Pohl et al., 2008). Chemotherapeutic agents can be given in an adjuvant form post-primary treatment (after surgery, anti-hormone therapy, and radiation) to reduce the risk of recurrence or to offer remedy care in patients with the advanced metastatic disease. In contrast, neoadjuvant chemotherapy is given before primary treatment

Drug therapy implies the treatment and prevention of CVDs and involves a variety of broadly acting classes of drugs. Here, we provided a brief description of a select number of commonly used drugs that are used in the treatment of CVDs. Anticoagulants, blood thinners such as heparin, decrease the clotting ability of blood. Although, anticoagulants may prevent clotting, they do not dissolve existing blood clots. Angiotensin converting enzyme (ACE) inhibitors dilate blood vessels and thereby decreases vascular resistance, which allows blood to flow more easily and relieves effort on the heart. These drugs can effectively be used to treat conditions such as high blood pressure and heart failure. Angiotensin-2 Receptor Antagonists (ARBs ) equilibrate heart and blood vessels and prevent an increase in blood pressure. In addition, ARBs are also used to treat high blood

of offenses, the type of drug, a number of drugs, and the intentions with it. Different therapies and rehabilitation centers offer treatment dealing with the drug that was used. While criminal activity regarding drug use should punish and dealt with, however, more people will benefit in the long term if criminal drug abusers receive treatment rather than just punishment. There are many possible treatments to try and help the person cope with getting away from drugs.

Current drug treatments are limited to those which only offer symptomatic relief that may not be seen in all patients rather than treatments which target and slow disease progression (Anand, Gill & Mahdi 2014; Nelson & Tabet 2015). Only two types of drugs have been approved for the symptomatic treatment of AD, acetylcholine esterase inhibitors (AChEIs) and ¬N-methyl-D-asparate (NMDA) receptor antagonists (Anand, Gill & Mahdi 2014; Nelson & Tabet 2015). There are three approved AChEIs, Donepezil (Aricept), Rivastigmine (Exelon) and Galantamine (Razadyne), along with a fourth cholinesterase inhibitor Tacrine which is no longer readily used due to hepatotoxicity (Watkins et al. 1994) and one NMDA, Memantine (Namenda) (Nelson & Tabet 2015).

Cranial Nerve I (smell) is intact, pt. can identify different smells. The patient was reactive to light touch. Was able to identify a paperclip in his hand, while eyes were closed, and guessed the correct number as I traced the number 8 on the palm of his hand. The temperature was within normal range. The pain was 3 /10. Was able to guide finger to his nose but couldn’t do a heel to shin test. Did not assess reflexes due to limitations. The patient was able to follow command. Speech is clear, and he makes sense. Prescribed Gabapentin 100 mg po for neuropathy. Labs: Glucose-174, AST-35, ALT-44, ALK-53, WBC-7.7, RBC-5.32, HGB-15.6, HCT-47.0, MCV-88.5, MCH-2904, MCHC-33.2, RDW-13.7, PLT 161, and MPV-8.9.