Thalidomide Thalidomide, a dangerous and extremely harmful teratogen, is one that has harmed children all over the world. Despite the fact that the US banned the chemical before it could be too widely distributed, it still affected thousands of families here that continue to live with the consequences today. Although Thalidomide is still used to successfully treat a variety of diseases and disorders, its history of unethical use resulting in the harm of thousands of fetuses should not be forgotten
Qianxi Wang RGA 6201 Professor Schalago 4 June 2016 Drug: Thalidomide Brand Name: THALOMID Trade Name: THALOMID Drug Class: Immunomodulatory Agent FDA Application Number:(NDA)020785 Sponsor/Company:Celgene Corporation INTRODUCTION THALOMID(thalidomide) is “an immunomodulatory agent”[1]. Thalidomide was first put into marker in 1957, which trade-name is Contergan under a German drug company-Chemie Grünenthal. The aim of this drug is used as a sedative or hypnotic, Chemie Grünenthal also claimed
“Thalidomide was introduced by the method of Russian roulette. Practically nothing was known about the drug at the time of its marketing.” A seemingly harmless drug with a dangerous secret, that was overlooked due to the corporate greed of Grünenthal, the company that synthesized thalidomide. A short time after its release, the drug became a sudden hit in countries across the world. It was known as the “wonder drug” due to the fact that scientists could not get a test rat to overdose. The illusion
studies because we cannot accurately predict how they will behave in people based on laboratory and animal studies In a study done on Thalidomide, a drug used for a sedative purpose, it was tested in rodent for safety and was later introduced into the market in October of 1957. There was extensive testing on rodent embryos to ensure it was safe. “Early laboratory
Thalidomide Disaster – How did it happen? Thalidomide, heralded as a wonder drug when it was first released into the market, was meant to alleviate morning sickness, lessen the effects of tumours in cancer patients and ease treatment of Leprosy and HIV/AIDS. Sounds great, doesn’t it? However, when the drug was released, it caused horrible birth defects to numerous babies, mainly in Continental Europe and affected many families. This was all caused by a slight difference in Chemical structure called
drug is called Thalidomide. Its popularity grew quickly because it is nonlethal, even in overdose, and a deadly quantity has yet to be found. Thalidomide is still used today, despite the extraordinary suffering, it has caused. Alas, Thalidomide was prescribed to pregnant women to help them through pregnancy symptoms, caused thousands of infants to be born with terrible deformities and deficient in countless areas, and has made a life of struggles for the children of Thalidomide. To begin with
were expected to be able to meet five outcomes: Demonstrate Knowledge, Conduct Group and Individual Research, Address Environmental Problems, Make Ethical Decisions In Care for Others, and Communicate in a Scholarly fashion. The purpose of this final assignment is to briefly describe how I met the student learning outcomes for the course. Demonstrate Knowledge / Conduct Group and Individual Research During the course, we completed two group projects and four individual assessments. Within Leadership
Thalidomide Paper Thalidomide is a drug that was invented in Germany in the 1950’s. It was originally intended to treat respiratory infections but during testing, it was noted that the drug worked to relieve morning sickness for pregnant women. This new reason allowed the drug to be prescribed to many new patients all over the world. Eventually Thalidomide was discovered to be causing birth defects in all of the pregnant women that were taking it. It caused the fetus to not develop correctly by
Hannah Olsen Thalidomide Paper 12/14/15 Thalidomide was a drug made to treat many different health problems and is now known as one of the worst teratogens in history. Thalidomide is most well-known to help with morning sickness in pregnant women, but that’s not what its original purpose was. The original purpose of thalidomide was to use for respiratory problems. Another use of thalidomide that was practiced was to “provide a safe sound sleep” (Thalidomide Victims Association of Canada, n.d.)
Hazardous Chemical Paper Introduction: In 1957, one of the worst chemical drugs was put on the market to result in a major tragedy in the Chemical field. This drug was Thalidomide. Thalidomide is a mutagen, studied in toxicology, in which it causes damage to the chemical material within an embryo when in development. This drug was created in West Germany by a pharmaceutical company, Chemie Grünenthal (Recognition of Thalidomide Defects, n.d.). During this time when Thalidomide was introduced to