The And Progression Of Schizophrenia

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Two-Hit Model of Schizophrenia, Discussion, Criticism, and Application to The Onset and Progression of Schizophrenia LA14495 University of Maryland Baltimore County December 2016 Abstract The purpose of this paper will be to discuss the two-hit model of schizophrenia, including what it is, how it may inform treatment and prevention of schizophrenia, how it applies to schizophrenia for the duration of onset and progression, and how various primary sources support or challenge the model. We are finding that despite some inconsistencies between numerous findings and the model, the model serves as a suitable general explanation of schizophrenia onset and progression. The two-hit model of schizophrenia proposes that disturbances to central nervous system development, leaves a person exposed to the onset of schizophrenia symptoms caused by various gene-environmental interactions. The disturbances to central nervous system development are the first hit in the two-hit model, and the gene-environmental interactions that are able to cause the onset of schizophrenia in conjunction with the disturbances to central nervous system development are the second hit in the two-hit model. Schizophrenia is usually grouped into three phases, the prodromal, active, and residual phases. Usually the prodromal phase occurs during the teen years or early twenties, and most of the time it occurs before the active phase. There is on occasion, mention of a fourth phase called
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