The Association Between Folate Deficiency And Depression

15. A light skin tone would be expected to be correlated with higher levels of folate because the darker you are, the UV rays deplete the folate levels.

22. All of the following types of drugs can interfere with the body's use of folate EXCEPT:

Cymbalta (Duloxetine) is a Serotonin Norepinephrine Reuptake Inhibitor (SNRI) use to treat depression (Breggin, 2013). There are several therapeutic and biological alternatives being implemented to control hopelessness. Many researcher are recommending other types of treatments before psychotropic therapy is implemented (O 'Mathuna & Larimore, 2010). Some of the therapeutic alternatives are Reflexology, Craniosacral Therapy (CST), Acupuncture, Exercise, Meditation and Direct Amino Acid Therapy Maintenance (Keegan, 2001). St John’s Wort, Passionflower, Valerian and Omega 3 fatty acids are a few of the biological options available to combat depression (Keegan, 2001). The dietary supplements tryptophan and

From the electronic database searches, several articles were appropriate. The first, "Vitamin D deficiency and depression in adults: systematic review and meta-analysis", was designed to find a relationship between Vitamin D and depression (Anglin, Samaan, Walter, & McDonald, 2013). Although, limited by the lack of random control trials, the data was presented in a uniform and consistent manner (Anglin et al., 2013). The results were in line with their goal, finding that low Vitamin D levels did correlate with increased depression (Anglin et al., 2013). Second, Meehan, and Penckofer, provided their inductive, exploratory opinion of "The role of Vitamin D in the aging adult" (2014). Although, the study was short and depression symptoms were self-reported, it, nevertheless, showed a correlation between low levels of Vitamin D and depression symptoms (Meehan, & Penckofer, 2014). The third article, "Vitamin D supplementation to prevent

As a result of a successful study on omega-3 fatty acids in adult major depressive disorder, they were determined to investigate the benefits omega-3 fatty acids have in childhood major depression. Major depressive disorder is common in children and adolescents. Frequently, it appears with poor psychosocial outcome, comorbid conditions, and high risk of suicide and substance abuse, which indicate that the condition needs to be treated. Researchers found that omega-3 fatty acids were effective in adult depression as an add-on therapy, and they inferred that it would have the similar effects in pediatric patients. The participants selected for this study were children between the ages of 6 and 12, and were submitted to the omega-3 trial for 16 weeks. Participants with unstable physical illness or psychiatric disorders other than anxiety, attention deficit hyperactivity disorder, dysthymia, or tic syndrome were excluded from the study. All participants needed at least one parent’s written informed consent and the consenting parent’s commitment to inform the other parent. The IV in this study was the Omega-3 acids treatment, and the DVs were the children with depressive disorder. Patients received two 500 mg or one 1,000 mg capsule of the treatment daily for 16 weeks, depending on their ability to

The diet is focused on plant-based foods, legumes, healthy fats such as olive oil and fish, limiting red meat and moderate alcohol consumption. Therefore, resulting in a diet full of B vitamins and omega-3 fatty acids which have shown to be protective against depression. Vitamin B12 and B6 are coenzymes involved in the conversion of homocysteine to methionine and cysteine. Methionine is an essential amino acid which supplies methyl molecules to the body. This is required for methylation which is the process by which methyl groups are added to a molecule.

Another important aspect of the results to note is that the two other groups, the ones who began taking the folic acid right after they were married and the ones who started taking the folic acid when they

Everyone will have a sad moment in their life, whether it is a death, a friend betraying he or she, or not getting accepted to the college of his or her choice. Depression can be described with many different words, but it will come down to sadness. People who live with depression will see lack of joy, energy, and happiness. They will not enjoy life, or living. They see it as pointless and useless. Many people will have a depressing moment at some point in their lifetime. The people who develop depression do not have to be poor or unsuccessful. They can be making millions a year and still be depressed, showing that money and success does not guarantee happiness. To be able to fully understand what depression is, one will need to know the

It is hard to distinguish in human trials whether a zinc deficiency is the cause of depressive symptoms or if it is a result of the onset of the illness itself. It is likely that one is not consuming the appropriate nutrients when he or she is depressed. It was shown however, in

Folic acid plays many important roles in the body. There is no doubting that it is essential. The reason that we need a constant stream of it is because it is not stored in large quantities in the body. It is water soluble. Fat soluble vitamins are stored for longer in our system. When ingested, the body uses what it can and the rest comes out in urine, in very little time the body will need more. We discussed how pregnant women get a proven benefit, and studies continue on its role in reducing risks of other diseases, but regardless of what additional benefits are found, it is clear that without folic acid in our bodies, we would not be alive. Folic acid aids in the production of red blood cells and the synthesis of DNA and RNA. Folate even has a role in the digestive system! It works with vitamins B12 and C to help the body digest and synthesize proteins. Lastly, folic acid helps tissues grow and cells function, it is an integral part of the body working as it should.

Major depression disorder (MDD), is known worldwide as one of the most predominant psychiatric disordered, which is characterized by the patient losing pleasure and interest in daily activities (ye, Qing, Zhang, & Liu, 2016). The patient also displays the following signs and symptoms of psychomotor retardation, insomnia, and exacerbating the experience of negative effects (Ye, Qing, Zhang, & Liu, 2016). Patients who are depressed normally have impaired role functioning, which reduces their quality of life (Gautam et al., 2017). It is currently considered to be the fourth leading cause of disability worldwide (Gautam et al., 2017). This

In Australia, the reasonableness and effectiveness of folic acid being mandatorily fortified to support healthy pregnancy when considering the occurrence of NTDS in Australian children due to the amount their mothers have consumed of folic acid during pregnancy. The main purpose for creating a mandatory policy to include folic acid to the wheat flour of non-organic bread in Australia is to reduce the incidence of NTDs across the nation. Substantial rates of NTDs occur worldwide as significantly more folate is needed early in pregnancy than in other life stages. This early stage of pregnancy is often when women are unaware that they are pregnant. The folate is required for the development of the embryonic neural tube, which develops into

Folate is a natural occurrence in foods such as beans and pulses (e.g. lentils and chickpeas), leafy green vegetables, broccoli, spinach, tuna and oranges (Tiran, 2000). Some foods are also fortified with folic acid such as cereals and bread. Late in the 1990’s United State scientists came to the realisation that despite the availability of folic acid in supplements as well as foods available in the supermarkets, people were still finding it a challenge to meet their daily folate requirement; with this in mind the United States of America implemented the folate fortification program (Latimes.com). For women of childbearing age, folic acid consumption needed to be increased so in January of 1998 the United States food and drug administration authorised a folic acid fortification of all products containing grain. The

Now lets get alittle bit into science. Folate helps in the production of red blood cells in bone marrow and heme that helps in transporting oxygen in the blood. In modern day medicine, doctors often advise patients with cardiovascular problems to take daily aspirin to improve blood flow and prevent

Also rodent studies showed a relationship between dietary zinc deficiency and the development of depressive behavior. It was found that zinc-deficient mice exhibit pro-depressive behavior observed as increased immobility time in the forced swim test (FST) and tail suspension test (TST) (Whittle N. 2009 36(1):147-58; Mlyniec K. 2012 64(2):249-55; Mlyniec K. 2012 64(3):567-75). Furthermore, these effects were reversed by chronic administration of desipramine (Tamano H. 2009 55,536–541; Whittle N. 2009 36(1):147-58). Studies performed in rats showed that dietary zinc deficiency induces anhedonia, social impairments and anxiety-like behavior, which are common, co-morbid symptoms of depression (Takeda A. 2007 12;177(1):1-6; Tassabehji NM. 2008 95,365–369) (Doboszewska…….).