The Between Opiates And Opioids

Analysis: Opioids are a class of drug that are medically used as very effective painkillers, like fentanyl and morphine, however, they are highly addictive and produce a feeling of euphoria (“Opioids”). This combination leads do a lot of abuse and dependency, where people take more than prescribed in order to feel better. People start off taking the opioid painkillers in order to not feel pain as prescribed by their doctors. Then, they end up getting addicted to them. There are also illicit opioids, such as heroin, that are also highly addictive and also lead to dependency and death (“Opioids”). These illicit versions are taken for recreational reasons, and are also often mixed with other drugs. The combination of taking an unregulated drug in conjunction with other drugs leads to a lot of overdoses.

Opiates are derived by opium. Opium is a gummy substance collected from the seed of the opium poppy. This

Opioids are classified as opium like compounds; some (ex. codeine and morphine) exist naturally in opium, which is a gummy substance derived from the seedpod of the opium poppy, indigenous to Southern Asia. Other opioids are of the synthetic category, such as methadone or fentanyl (opioidaddictionsource.com). Though the use of prescription opioids may be well intended, due to their effect on the brain chemistry, it is fairly common for one to become addicted to them; America is amidst a raging prescription opioid epidemic, in fact.

Oxycodone is the main drug I am concentrating on even though there are many opiates or schedule II drugs that are considered Opioids. Oxycodone was first created as part of an effort to find non-addictive alternatives to morphine and heroin, which were commonly used in medicine before World War I. Oxycodone is an opioid analgesic, ?Pain Killer? that is most often prescribed to control moderate to severe pain that must not be used with other medications. It is a slightly synthetic opiate that was created in 1916. The chemicals found in Poppy plants also make as morphine and heroin. Opiate:?A drug (such as morphine, codeine or heroin) containing or derived from opium or the opium poppy, used to alleviate pain, or induce sleep or euphoria. "Some Facts You Should Know About the History of Oxycodone." A Forever Recovery. 2014. Web. 10 Mar. 2016. Opioid:?A synthetic or semi-synthetic substance producing an opium-like effect, often prescribed for the alleviation of moderate to severe pain; a prescription painkiller in the opiate class.

Opioids are a class of drugs that are designed to relieve pain. They are synthetic forms of the naturally occurring opiate opium along with morphine and codeine, which are parts of the opium poppy. Prescription opioids include the painkillers hydrocodone (Vicodin), oxycodone (OxyContin, Percocet), fentanyl (Duragesic), meperidine (Demerol), and hydromorphone (Dilaudid), amongst others. Opioids of this variety are prescribed for a variety of reasons ranging from severe acute pain resulting from injury to post surgery pain relief. Illicit opioids include heroin and any opioids that are not taken are prescribed. While helpful in treating pain that needs immediate attention, prescription opioids are not ideal to treat chronic pain. Opioids, both prescribed and illicit, are highly addictive and potentially dangerous.

For thousands of years, opiates have been used in the treatment of pain. Opium is believed to have been discovered 6000 BC, and since then, it has had a huge impact on both medicine and the recreations of those seeking euphoria. More recent than the ancient discovery of natural opium are the derivatives of opium, such as the alkaloids morphine, codeine, and thebaine. From these alkaloids, semi-synthetic opiates can by synthesized, such as hydrocodone, and oxycodone. Synthetic opioids are also quite prevalent, which include fentanyl and tramadol. Opium can also be processed into heroin, a morphine derivative. As advancements were made in science and engineering to allow for a wider distribution and usage of opiates, the problems of dependence and overdose also increased drastically. According to Hart and Ksir (2013, p. 302), the invention of the hypodermic needle for intravenous administration of morphine and other drugs allowed for a much faster and more potent dose of the drug. With this increased potency came an increase in the possibility of a recreational intravenous user to overdose. Hart also mentions that some of the wars surrounding the era of the synthesis of morphine may have contributed to the rise of morphine, seeing as a medic soldier’s motto was always “first provide relief” (2013). This relief-driven attitude and extensive use of opioid analgesics in medicine during the time, in addition to the large amount of patent medicines and remedies on the market may

Oxycodone is the main drug I am concentrating on even though there are many opiates or schedule II drugs that are considered Opioids. Oxycodone was created during the process to find a drug that was not addictive like morphine and heroin, which were commonly used in medicine before World War I(? A Forever Recovery. 2014. Web. 10 Mar. 2016?). Oxycodone is an opioid analgesic, ?Pain Killer? that is most often prescribed to control moderate to severe pain that must not be used with other medications. It is a slightly synthetic opiate that was created in 1916. The chemicals found in Poppy plants also make as morphine and heroin. Opiate:?A drug (such as morphine, codeine or heroin) containing or made from opium or the opium poppy, used to alleviate pain, or induce sleep or euphoria. ( A Forever Recovery. 2014. Web. 10 Mar. 2016). Opioid:?A synthetic or semi-synthetic substance producing an opium-like effect, often prescribed for the alleviation of moderate to severe pain; a prescription painkiller in the opiate class.

Individuals who use Opioids are Addicts. The history of this very debatable topic is very educational and interesting. Opioids are drugs that are prescribed for severe to chronic pain, some examples of opioids are: morphine,?methadone, Buprenorphine,?hydrocodone, and?oxycodone.?Heroin?is also an opioid and is illegal. Opioid drugs sold under brand names include: OxyContin?,?Percocet?, Palladone?(taken off the market 7/2005),Vicodin?, Percodan?, Tylox? and?Demerol? among others. These drugs are also classified as a schedule II drug. Substances in this schedule have a high potential for abuse which may lead to severe psychological or physical dependence. Substances are placed in their respective schedules based on whether they have a currently accepted medical use in treatment in the United States, their relative abuse potential, and likelihood

Today there are many different drugs in circulation. Those drugs are not always used properly or legally. Opioids present a contradiction in legal history along with pharmaceutical history. Opioids have a long history, starting with the creation of heroin, as a cough suppressant. Since then the federal government and FDA have stepped in to remove heroin from the public and come up with new medicines that seem to mimic the effect of heroin but be safe enough to sell on a public scale. Unfortunately even as medicines are made for public use, these medications are still proven to be prone to addiction and even overdose. These FDA approved opioids are gateway drugs to heroin. There is a pattern among those

There are many various kinds of prescription of pain relievers, which include: opioids, corticosteroids, antidepressants and anticonvulsants (anti-seizure medications). Among them I would like to focus on opioid medications and its side effects. Opioid medications are narcotic pain medications that contain natural poppy plant, synthetic opiates such as; methadone, fentanyl, tapentadol and tramadol, as well as the semi- synthetic opioids such as; oxycodone, hydrocodone, oxymorphone, hydromorphone and heroin. Opioid prescriptions are morphine (C17H19NO3), heroin (C21H23NO5), codeine (C18H21NO3) and thebaine (C19H21NO3). They are highly addictive substances are called opiates. Opioid medications have been used for hundreds and thousands of years to treat both pain and mental health problems. It is also use in a short-term pain after surgery. According to the survey in the past two decades, the prescription of opioid in the United States has been increased to the higher levels that is more than 600% (Paulozzi & Baldwin, 2012). However, that opioid medications are very dangerous to the patients’ respiratory system, other parts of the internal body and even can cause death. It should be only being use after wise discernment and with a great care.

Prescription painkillers go by many names, opiates, opioids, and narcotics. There are also types of opiates; some legal and some not. Some types of legal opiates include: codeine, hydrocodone, oxycodone, morphine, hydromorphone, and methadone (MSU). Each one of these have different potencies and side effects, but they are all equally as dangerous as the next one. There are too many of these dangerous drugs, therefore, people believe they are safe. The problem is that they are not safe; these drugs need to be banned immediately.

Opioids attach themselves to specific proteins called opioid receptors. These opioid receptors are found throughout the body including the brain, spinal cord, and GI tract. When an opioid attaches to a receptor, it can reduce the perception of pain. Through this coupling with receptors, opioids can also produce drowsiness, mental confusion, nausea, constipation, and, depending upon the amount of drug taken, can stop respiration leading to death (overdosing).

The way opioids work is by attaching to one of three different type of neuronal receptors located in the brain and spinal cord (and possibly the peripheral nervous system). The three

Another potential explanation for this finding is estrogen's role in internalization of opioid receptors. While the exact mechanism of tolerance to opioids in general remains a controversial topic, one

Synthetic and semi-synthetic opioids are widely used for their analgesic actions. There are endogenous opiods that are naturally occruing compounds that are found in plants and produced in the body as mentioned prior. They have variable potency most likely bound by different opioate receptors. They help in the modulation of pain and have effects in the cardiovascular (CV) system, but have no role clinically.